State estimation for high-speed multifrequency atomic force microscopy

A fundamental component in the z-axis feedback loop of an atomic force microscope (AFM) operated in dynamic mode is the lock-in amplifier to obtain amplitude and phase of the high-frequency cantilever deflection signal. While this narrowband demodulation technique is capable of filtering noise far away from the carrier and modulation frequency, its performance is ultimately bounded by the bandwidth of its low-pass filter which is employed to suppress the frequency component at twice the carrier frequency. Moreover, multiple eigenmodes and higher harmonics are used for imaging in modern multifrequency AFMs, which necessitates multiple lock-in amplifiers to recover the respective amplitude and phase information. We propose to estimate amplitude and phase of multiple frequency components with a linear time-varying Kalman filter which allows for an efficient implementation on a Field Programmable Gate Array (FPGA). While experimental results for the single mode case have already proven to increase the imaging bandwidth in tapping-mode AFM, multifrequency simulations promise further improvement in imaging flexibility.

[1]  Manfred Morari,et al.  Model Predictive Climate Control of a Swiss Office Building: Implementation, Results, and Cost–Benefit Analysis , 2016, IEEE Transactions on Control Systems Technology.

[2]  Daniel Y. Abramovitch,et al.  Low latency demodulation for Atomic Force Microscopes, Part I efficient real-time integration , 2011, Proceedings of the 2011 American Control Conference.

[3]  Karl Deisseroth,et al.  Corrigendum: Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression , 2015, Nature Communications.

[4]  Donald A. Chernoff,et al.  Scanning force microscopy; with applications to electric, magnetic, and atomic forces , 1992 .

[5]  T. Ando,et al.  A high-speed atomic force microscope for studying biological macromolecules , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[6]  E. Nauman,et al.  Mapping nanomechanical properties of live cells using multi-harmonic atomic force microscopy. , 2011, Nature nanotechnology.

[7]  Lawrence Markus,et al.  Global stability criteria for differential systems. , 1960 .

[8]  S. O. Reza Moheimani,et al.  A Kalman Filter for Amplitude Estimation in High-Speed Dynamic Mode Atomic Force Microscopy , 2016, IEEE Transactions on Control Systems Technology.

[9]  Gerber,et al.  Atomic Force Microscope , 2020, Definitions.

[10]  T. Ando,et al.  High-speed atomic force microscopy for nano-visualization of dynamic biomolecular processes , 2008 .

[11]  Paul Van Dooren,et al.  Computational methods for periodic systems - An overview , 2001 .

[12]  V. Elings,et al.  Fractured polymer/silica fiber surface studied by tapping mode atomic force microscopy , 1993 .

[13]  S. O. Reza Moheimani,et al.  Multimode $Q$ Control in Tapping-Mode AFM: Enabling Imaging on Higher Flexural Eigenmodes , 2016, IEEE Transactions on Control Systems Technology.

[14]  Ricardo Garcia,et al.  The emergence of multifrequency force microscopy. , 2012, Nature nanotechnology.

[15]  Robert Forchheimer,et al.  Improving image contrast and material discrimination with nonlinear response in bimodal atomic force microscopy , 2015, Nature Communications.

[16]  Adly Girgis,et al.  Optimal Estimation Of Voltage Phasors And Frequency Deviation Using Linear And Non-Linear Kalman Filtering: Theory And Limitations , 1984, IEEE Transactions on Power Apparatus and Systems.

[17]  Toshio Ando,et al.  High-speed atomic force microscopy coming of age , 2012, Nanotechnology.

[18]  Javier Tamayo,et al.  Effects of elastic and inelastic interactions on phase contrast images in tapping-mode scanning force microscopy , 1997 .

[19]  S O R Moheimani,et al.  A high-bandwidth amplitude estimation technique for dynamic mode atomic force microscopy. , 2014, The Review of scientific instruments.

[20]  Richard A. Brown,et al.  Introduction to random signals and applied kalman filtering (3rd ed , 2012 .