Numerical modeling of susceptibility‐related MR signal dephasing with vessel size measurement: Phantom validation at 3T

MRI is used to obtain quantitative oxygenation and blood volume information from the susceptibility‐related MR signal dephasing induced by blood vessels. However, analytical models that fit the MR signal are usually not accurate over the range of small blood vessels. Moreover, recent studies have demonstrated limitations in the simultaneous assessment of oxygenation and blood volume. In this study, a multiparametric MRI framework that aims to measure vessel radii in addition to magnetic susceptibility and volume fraction was introduced.

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