Superadditive Information from Simultaneous MEG/EEG Data

Although MEG and EEG measurement modalities are empirically distinct, there is a theoretically unified statistical-biophysical framework for posing and (in a limited sense) solving the electromagnetic inverse problem. In addition, biomagnetic and bioelectric measurements are differentially sensitive to the same type of intracranial signals, i.e., macroscopic ionic source currents. Since MEG and EEG share a common foundation and probably provide complementary information about the same kind of source signals, a truly integrated electromagnetic source imaging (EMSI) modality appears theoretically immanent. In practice, EMSI requires combined analysis of MEG and EEG acquired (in the ideal case) simultaneously.