High-energy x-ray phase tomography using grating interferometer with structured anode x-ray source

Talbot-Lau interferometers are widely used for X-ray phase imaging/tomography. For thick objects or materials including metals, high-energy X-rays should be used. However, absorption gratings with extremely high aspect-ratios (AR) are necessary but are hard to be fabricated by current microfabrication techniques. As an approach without using high-AR absorption gratings, we developed the high-energy X-ray phase imaging device with a structured anode X-ray source, which has tungsten target array embedded in a diamond substrate. X-rays are emitted from the tungsten region, and therefore G0 can be omitted. We will show the results of high-energy X-ray phase imaging and tomography performed with a design energy of 82 keV.

[1]  Atsushi Momose,et al.  Grating-Based X-ray Phase Imaging Using Multiline X-ray Source , 2009 .

[2]  A. Momose Recent Advances in X-ray Phase Imaging , 2005 .

[3]  Franz Pfeiffer,et al.  X-ray phase imaging with a grating interferometer. , 2005, Optics express.

[4]  A. Momose,et al.  On the origin of visibility contrast in x-ray Talbot interferometry. , 2010, Optics express.

[5]  M. Strobl General solution for quantitative dark-field contrast imaging with grating interferometers , 2014, Scientific reports.

[6]  Kazuhiko Omote,et al.  Hard x-ray phase contrast imaging using a tabletop Talbot-Lau interferometer with multiline embedded x-ray targets. , 2013, Optics letters.

[7]  Franz Pfeiffer,et al.  Experimental results from a preclinical X-ray phase-contrast CT scanner , 2012, Proceedings of the National Academy of Sciences.

[8]  B. Müller,et al.  Implementation of a double-grating interferometer for phase-contrast computed tomography in a conventional system nanotom® m , 2018, APL bioengineering.

[9]  O. Bunk,et al.  Hard-X-ray dark-field imaging using a grating interferometer. , 2008, Nature materials.

[10]  Franz Pfeiffer,et al.  Quantitative X-ray phase-contrast computed tomography at 82 keV. , 2013, Optics express.

[11]  Yijin Liu,et al.  High-resolution multicontrast tomography with an X-ray microarray anode–structured target source , 2021, Proceedings of the National Academy of Sciences.

[12]  Gerhard Martens,et al.  Slit-scanning differential x-ray phase-contrast mammography: proof-of-concept experimental studies. , 2015, Medical physics.

[13]  Franz Pfeiffer,et al.  Inverse geometry for grating-based x-ray phase-contrast imaging , 2009 .

[14]  O. Bunk,et al.  Phase retrieval and differential phase-contrast imaging with low-brilliance X-ray sources , 2006 .

[15]  C. David,et al.  Differential x-ray phase contrast imaging using a shearing interferometer , 2002 .

[16]  Jimpei Harada,et al.  X-ray phase contrast imaging by compact Talbot-Lau interferometer with a single transmission grating. , 2014, Optics letters.

[17]  Development of X-ray phase CT with a hybrid configuration of Lau and Talbot-Lau interferometers. , 2020, Journal of X-ray science and technology.

[18]  Tadashi Hattori,et al.  X-ray phase imaging: from synchrotron to hospital , 2014, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

[19]  刘鑫,et al.  Development of x-ray scintillator functioning also as an analyser grating used in grating-based x-ray differential phase contrast imaging , 2011 .

[20]  Characterization of medical and biological samples with a Talbot–Lau grating interferometer μXCT in comparison to reference methods , 2016 .

[21]  Structured scintillator for hard x-ray grating interferometry , 2011 .

[22]  Robert D. Speller,et al.  "Edge illumination" in X-ray Phase Contrast Imaging , 2012 .

[23]  Franz Pfeiffer,et al.  Quantitative x-ray dark-field computed tomography , 2010, Physics in medicine and biology.

[24]  Improvement in quantitative phase mapping by a hard x-ray microscope equipped with a Lau interferometer , 2019, Optica.

[25]  Atsushi Momose,et al.  Fabrication of diffraction grating for X-ray Talbot interferometer , 2007 .

[26]  Franz Pfeiffer,et al.  X-ray dark-field imaging of the human lung—A feasibility study on a deceased body , 2018, PloS one.

[27]  F. Pfeiffer,et al.  X-ray grating interferometry at photon energies over 180 keV , 2015 .

[28]  Ashley F. Stein,et al.  Interpretation of dark-field contrast and particle-size selectivity in grating interferometers. , 2011, Applied optics.

[29]  Juerg Leuthold,et al.  High aspect ratio gratings for X-ray phase contrast imaging , 2012 .

[30]  Fabrication of High Aspect Ratio X-ray Grating Using X-ray Lithography , 2009 .

[31]  Atsushi Momose,et al.  X-ray Phase Imaging Using Lau Effect , 2011 .

[32]  Atsushi Momose,et al.  Demonstration of X-Ray Talbot Interferometry , 2003 .

[33]  Atsushi Momose,et al.  Effect of beam hardening on a visibility-contrast image obtained by X-ray grating interferometry. , 2015, Optics express.

[34]  Richard J. Fitzgerald,et al.  Phase‐Sensitive X‐Ray Imaging , 2000 .

[35]  Tal Z. Sholklapper,et al.  The relationship between coefficient of restitution and state of charge of zinc alkaline primary LR6 batteries , 2015 .