Heterotopic pancreatic tissue in the cystic duct: complicating factor or coexisting pathology.

The case of a 75-year-old female suffering from recurrent abdominal pain and nausea is presented. Ultrasound showed gallstones without inflammation of the gallbladder. The patient underwent laparoscopic cholecystectomy and her symptoms resolved. Histological examination of the operation specimen disclosed heterotopic pancreatic tissue within the cystic duct. An accurate clinical diagnosis of pancreatic heterotopia is difficult. The deep submucosal or intramural location of the lesion may hamper retrieval of representative biopsy material. Indications for surgery or endoscopic resection include symptomatic lesions as well as cases of unclear histological examination in order to distinguish pancreatic heterotopia from other tumors.

[1]  R. Barranco,et al.  Heterotopic pancreas: a difficult diagnosis , 2010, Endoscopy.

[2]  D. Bartsch,et al.  [Heterotopic pancreatic tissue in the bifurcation of the bile duct : Rare diagnosis mimicking a Klatskin tumour]. , 2010, Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen.

[3]  D. Bartsch,et al.  Heterotopes Pankreasgewebe in der Hepatikusgabel , 2009, Der Chirurg.

[4]  Hai-tao Zheng,et al.  Gastric outlet obstruction caused by heterotopic pancreas: A case report and a quick review. , 2008, World journal of gastroenterology.

[5]  G. Paraskevas,et al.  Carcinoma developing in ectopic pancreatic tissue in the stomach: a case report , 2008, Cases journal.

[6]  M. Shiwani,et al.  Heterotopic pancreas of the gallbladder associated with chronic cholecystitis. , 2008, JOP : Journal of the pancreas.

[7]  E. Katsogridakis,et al.  Heterotopic pancreas in the stomach: a case report and literature review. , 2007, World journal of gastroenterology.

[8]  R. Lindtner,et al.  Cytokeratin 7 immunostaining facilitates recognition of pancreatic heterotopia in gastric biopsies , 2007, Pathology international.

[9]  P. Appel,et al.  [Heterotopic pancreas in the gallbladder. Diagnosis, therapy, and course of a rare developmental anomaly of the pancreas]. , 2007, Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen.

[10]  S. Bozova,et al.  An unusual cause of cholecystitis: heterotopic pancreatic tissue in the gallbladder. , 2007, World journal of gastroenterology.

[11]  S. Gananadha,et al.  A unique case of pancreatitis and retention cyst in esophageal heterotopic pancreas. , 2005, Surgical laparoscopy, endoscopy & percutaneous techniques.

[12]  M. Álvarez,et al.  Heterotopic pancreatic tissue in the gallbladder , 1993, Pediatric Surgery International.

[13]  R. Ahıskalı,et al.  An unusual cause of hydropic gallbladder and biliary colic — Heterotopic pancreatic tissue in the cystic duct: Report of a case and review of the literature , 2004, Surgery Today.

[14]  F. Maassarani,et al.  Cholecystitis Associated with Heterotopic Pancreas , 2003, Acta chirurgica Belgica.

[15]  B. Bhana,et al.  Heterotopic pancreas--an unusual cause of cholecystitis. , 1999, South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie.

[16]  L. Sobin,et al.  Carcinoma in jejunal pancreatic heterotopia. , 1999, Archives of pathology & laboratory medicine.

[17]  T. Kotsis,et al.  Aberrant pancreas in the gallbladder wall , 1997, European Radiology.

[18]  J. Dixon,et al.  The clinical significance of heterotopic pancreas in the gastrointestinal tract , 1981, The British journal of surgery.

[19]  A. Qizilbash.  Acute pancreatitis occurring in heterotopic pancreatic tissue in the gallbladder. , 1976, Canadian journal of surgery. Journal canadien de chirurgie.