Calsyntenins Function as Synaptogenic Adhesion Molecules in Concert with Neurexins.

[1]  Steven A. Connor,et al.  The Specific α-Neurexin Interactor Calsyntenin-3 Promotes Excitatory and Inhibitory Synapse Development , 2013, Neuron.

[2]  Ji Won Um,et al.  LAR-RPTPs: synaptic adhesion molecules that shape synapse development. , 2013, Trends in cell biology.

[3]  T. Südhof,et al.  Membrane-Tethered Monomeric Neurexin LNS-Domain Triggers Synapse Formation , 2013, The Journal of Neuroscience.

[4]  F. Calahorro,et al.  Human alpha‐ and beta‐NRXN1 isoforms rescue behavioral impairments of Caenorhabditis elegans neurexin‐deficient mutants , 2013, Genes, brain, and behavior.

[5]  Hiroshi Takahashi,et al.  Calsyntenin-3 C-terminal fragment accumulates in dystrophic neurites surrounding aβ plaques in tg2576 mouse and Alzheimer disease brains: its neurotoxic role in mediating dystrophic neurite formation. , 2013, The American journal of pathology.

[6]  Eunjoon Kim,et al.  Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases , 2013, Proceedings of the National Academy of Sciences.

[7]  Dongmin Lee,et al.  MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development , 2012, Proceedings of the National Academy of Sciences.

[8]  J. Kaplan,et al.  Neurexin and Neuroligin Mediate Retrograde Synaptic Inhibition in C. elegans , 2012, Science.

[9]  Toshiharu Suzuki,et al.  Constitutive Cleavage of the Single-Pass Transmembrane Protein Alcadeinα Prevents Aberrant Peripheral Retention of Kinesin-1 , 2012, PloS one.

[10]  Nils Brose,et al.  The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses , 2012, Current Opinion in Neurobiology.

[11]  T. Südhof,et al.  Synaptic cell adhesion. , 2012, Cold Spring Harbor perspectives in biology.

[12]  P. Francis,et al.  Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production , 2012, Human molecular genetics.

[13]  D. Geschwind,et al.  Proteomic changes in cerebrospinal fluid of presymptomatic and affected persons carrying familial Alzheimer disease mutations. , 2012, Archives of neurology.

[14]  T. Südhof,et al.  Neuroligins/LRRTMs prevent activity- and Ca2+/calmodulin-dependent synapse elimination in cultured neurons , 2011, The Journal of cell biology.

[15]  Alessio Vagnoni,et al.  Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1 , 2011, Journal of Cell Science.

[16]  N. Bot,et al.  Processing of the Synaptic Cell Adhesion Molecule Neurexin-3β by Alzheimer Disease α- and γ-Secretases* , 2010, The Journal of Biological Chemistry.

[17]  J. Kauer,et al.  Drugs of abuse and stress impair LTP at inhibitory synapses in the ventral tegmental area , 2010, The European journal of neuroscience.

[18]  T. Südhof,et al.  Neurexins Physically and Functionally Interact with GABAA Receptors , 2010, Neuron.

[19]  Shu-Chen Li,et al.  KIBRA and CLSTN2 polymorphisms exert interactive effects on human episodic memory , 2010, Neuropsychologia.

[20]  Thomas C. Südhof,et al.  LRRTM2 Functions as a Neurexin Ligand in Promoting Excitatory Synapse Formation , 2009, Neuron.

[21]  T. Südhof,et al.  Neuroligin‐1 performs neurexin‐dependent and neurexin‐independent functions in synapse validation , 2009, The EMBO journal.

[22]  T. Südhof,et al.  Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments , 2009, Proceedings of the National Academy of Sciences.

[23]  Zhiping P. Pang,et al.  Synaptotagmin-1 functions as the Ca2+-sensor for spontaneous release , 2009, Nature Neuroscience.

[24]  K. Suk,et al.  Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseases , 2009, Brain Research.

[25]  D. D. de Quervain,et al.  A Conserved Function of C. elegans CASY-1 Calsyntenin in Associative Learning , 2009, PloS one.

[26]  P. Hulpiau,et al.  Molecular evolution of the cadherin superfamily. , 2009, The international journal of biochemistry & cell biology.

[27]  T. Südhof Neuroligins and neurexins link synaptic function to cognitive disease , 2008, Nature.

[28]  Jyothi Arikkath,et al.  Cadherins and catenins at synapses: roles in synaptogenesis and synaptic plasticity , 2008, Trends in Neurosciences.

[29]  Harald Hutter,et al.  CASY-1, an ortholog of calsyntenins/alcadeins, is essential for learning in Caenorhabditis elegans , 2008, Proceedings of the National Academy of Sciences.

[30]  A. Craig,et al.  Induction of GABAergic Postsynaptic Differentiation by α-Neurexins* , 2008, Journal of Biological Chemistry.

[31]  T. Südhof,et al.  Activity-Dependent Validation of Excitatory versus Inhibitory Synapses by Neuroligin-1 versus Neuroligin-2 , 2007, Neuron.

[32]  T. Südhof,et al.  Deletion of α‐neurexins does not cause a major impairment of axonal pathfinding or synapse formation , 2007, The Journal of comparative neurology.

[33]  Zhiping P. Pang,et al.  Monitoring synaptic transmission in primary neuronal cultures using local extracellular stimulation , 2007, Journal of Neuroscience Methods.

[34]  Yu Ohsugi,et al.  The novel cargo Alcadein induces vesicle association of kinesin‐1 motor components and activates axonal transport , 2007, The EMBO journal.

[35]  Ann Marie Craig,et al.  Neurexin–neuroligin signaling in synapse development , 2007, Current Opinion in Neurobiology.

[36]  Jason J. Corneveaux,et al.  Common Kibra Alleles Are Associated with Human Memory Performance , 2006, Science.

[37]  P. Sonderegger,et al.  Calsyntenin-1 docks vesicular cargo to kinesin-1. , 2006, Molecular biology of the cell.

[38]  Toshiharu Suzuki,et al.  Trafficking of Alzheimer's disease-related membrane proteins and its participation in disease pathogenesis. , 2006, Journal of biochemistry.

[39]  Eunjoon Kim,et al.  Organization of the Presynaptic Active Zone by ERC2/CAST1-Dependent Clustering of the Tandem PDZ Protein Syntenin-1 , 2006, The Journal of Neuroscience.

[40]  L. Vinadé,et al.  Preparation of postsynaptic density fraction from hippocampal slices and proteomic analysis. , 2006, Biochemical and biophysical research communications.

[41]  J. Pettitt The cadherin superfamily. , 2005, WormBook : the online review of C. elegans biology.

[42]  Thomas C. Südhof,et al.  A Splice Code for trans-Synaptic Cell Adhesion Mediated by Binding of Neuroligin 1 to α- and β-Neurexins , 2005, Neuron.

[43]  P. Scheiffele,et al.  Control of Excitatory and Inhibitory Synapse Formation by Neuroligins , 2005, Science.

[44]  Marc G Caron,et al.  Identification of PSD-95 as a Regulator of Dopamine-Mediated Synaptic and Behavioral Plasticity , 2004, Neuron.

[45]  S. Tomita,et al.  Novel Cadherin-related Membrane Proteins, Alcadeins, Enhance the X11-like Protein-mediated Stabilization of Amyloid β-Protein Precursor Metabolism* , 2003, Journal of Biological Chemistry.

[46]  L. Brodin Faculty Opinions recommendation of Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis. , 2003 .

[47]  T. Südhof,et al.  α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis , 2003, Nature.

[48]  R. Weinberg,et al.  Interaction between Liprin-α and GIT1 Is Required for AMPA Receptor Targeting , 2003, The Journal of Neuroscience.

[49]  P. Sonderegger,et al.  The Calsyntenins—A Family of Postsynaptic Membrane Proteins with Distinct Neuronal Expression Patterns , 2002, Molecular and Cellular Neuroscience.

[50]  T. Südhof,et al.  A stoichiometric complex of neurexins and dystroglycan in brain , 2001, The Journal of cell biology.

[51]  Guosong Liu,et al.  Regulation of Dendritic Spine Morphology and Synaptic Function by Shank and Homer , 2001, Neuron.

[52]  P. Sonderegger,et al.  Calsyntenin-1, a Proteolytically Processed Postsynaptic Membrane Protein with a Cytoplasmic Calcium-Binding Domain , 2001, Molecular and Cellular Neuroscience.

[53]  R. Fetter,et al.  Neuroligin Expressed in Nonneuronal Cells Triggers Presynaptic Development in Contacting Axons , 2000, Cell.

[54]  T. Südhof,et al.  Cartography of neurexins: More than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons , 1995, Neuron.

[55]  A. Craig,et al.  Induction of GABAergic postsynaptic differentiation by alpha-neurexins. , 2008, The Journal of biological chemistry.

[56]  P. Scheiffele,et al.  Mixed-culture assays for analyzing neuronal synapse formation , 2007, Nature Protocols.

[57]  M. Takeichi The cadherin superfamily in neuronal connections and interactions , 2007, Nature Reviews Neuroscience.

[58]  T. Südhof,et al.  A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins. , 2005, Neuron.

[59]  R. Weinberg,et al.  Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting. , 2003, The Journal of neuroscience : the official journal of the Society for Neuroscience.