Involvement of polypyrimidine tract-binding protein (PTBP1) in maintaining breast cancer cell growth and malignant properties

[1]  N. Yoshida,et al.  PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. , 2013, Cerebral cortex.

[2]  W. T. Beck,et al.  A High-Throughput Assay to Identify Small-Molecule Modulators of Alternative Pre-mRNA Splicing , 2013, Journal of biomolecular screening.

[3]  A. Jemal,et al.  Cancer statistics, 2013 , 2013, CA: a cancer journal for clinicians.

[4]  Steven J. M. Jones,et al.  Comprehensive molecular portraits of human breast tumours , 2013 .

[5]  Steven J. M. Jones,et al.  Comprehensive molecular portraits of human breast tumors , 2012, Nature.

[6]  C. Dang,et al.  Otto Warburg's contributions to current concepts of cancer metabolism , 2011, Nature Reviews Cancer.

[7]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[8]  J. Manley,et al.  Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA. , 2010, Cancer research.

[9]  Frank McCormick,et al.  The molecular pathology of cancer , 2010, Nature Reviews Clinical Oncology.

[10]  M. Assanah,et al.  HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer , 2010, Nature.

[11]  A. Krainer,et al.  The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism , 2010, Proceedings of the National Academy of Sciences.

[12]  V Clower Cynthia,et al.  選択的スプライシングレプレッサーhnRNP A1/A2とPTBはピルビン酸キナーゼアイソフォーム発現と細胞代謝に影響する , 2010 .

[13]  M. Stack,et al.  Polypyrimidine Tract-binding Protein (PTB) Differentially Affects Malignancy in a Cell Line-dependent Manner* , 2008, Journal of Biological Chemistry.

[14]  Thomas D. Schmittgen,et al.  Analyzing real-time PCR data by the comparative CT method , 2008, Nature Protocols.

[15]  J. Russo,et al.  SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis , 2008, Nature.

[16]  Ru Wei,et al.  The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth , 2008, Nature.

[17]  Lin Zhang,et al.  The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis , 2008, Nature Cell Biology.

[18]  David B Sacks,et al.  IQGAP1 Stimulates Proliferation and Enhances Tumorigenesis of Human Breast Epithelial Cells* , 2008, Journal of Biological Chemistry.

[19]  W. Gerald,et al.  Endogenous human microRNAs that suppress breast cancer metastasis , 2008, Nature.

[20]  J. Russo,et al.  SATB 1 reprogrammes gene expression to promote breast tumour growth and metastasis , 2008 .

[21]  S. Auweter,et al.  Structure-function relationships of the polypyrimidine tract binding protein , 2008, Cellular and Molecular Life Sciences.

[22]  J. Coon,et al.  Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro , 2007, Oncogene.

[23]  Tyra Hall-Pogar,et al.  Specific trans-acting proteins interact with auxiliary RNA polyadenylation elements in the COX-2 3'-UTR. , 2007, RNA.

[24]  C. Morrison,et al.  FOXP3 Is an X-Linked Breast Cancer Suppressor Gene and an Important Repressor of the HER-2/ErbB2 Oncogene , 2007, Cell.

[25]  Eric S. Lander,et al.  Integrative Genomic Approaches Identify IKBKE as a Breast Cancer Oncogene , 2007, Cell.

[26]  Christopher W. J. Smith,et al.  Novel modes of splicing repression by PTB. , 2006, Trends in biochemical sciences.

[27]  K. Preissner,et al.  Evidence for an RNA chaperone function of polypyrimidine tract-binding protein in picornavirus translation. , 2005, RNA.

[28]  Andy J. Minn,et al.  Genes that mediate breast cancer metastasis to lung , 2005, Nature.

[29]  K. Kaibuchi,et al.  IQGAP1: a key regulator of adhesion and migration , 2005, Journal of Cell Science.

[30]  J. Coon,et al.  Alternative Splicing of the Multidrug Resistance Protein 1/ATP Binding Cassette Transporter Subfamily Gene in Ovarian Cancer Creates Functional Splice Variants and Is Associated with Increased Expression of the Splicing Factors PTB and SRp20 , 2004, Clinical Cancer Research.

[31]  M. Wollerton,et al.  Polypyrimidine Tract Binding Protein Modulates Efficiency of Polyadenylation , 2004, Molecular and Cellular Biology.

[32]  G. Goodall,et al.  A multi-protein complex containing cold shock domain (Y-box) and polypyrimidine tract binding proteins forms on the vascular endothelial growth factor mRNA. Potential role in mRNA stabilization. , 2004, European journal of biochemistry.

[33]  M. Wiznerowicz,et al.  Conditional Suppression of Cellular Genes: Lentivirus Vector-Mediated Drug-Inducible RNA Interference , 2003, Journal of Virology.

[34]  P. Yaswen,et al.  Loss of p53 function accelerates acquisition of telomerase activity in indefinite lifespan human mammary epithelial cell lines , 2003, Oncogene.

[35]  Anne E Willis,et al.  The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr. , 2003, Molecular cell.

[36]  R. Cron,et al.  Delineation of a Novel Pathway That Regulates CD154 (CD40 Ligand) Expression , 2003, Molecular and Cellular Biology.

[37]  N. Welsh,et al.  Hypoxia May Increase Rat Insulin mRNA Levels by Promoting Binding of the Polypyrimidine Tract-binding Protein (PTB) to the Pyrimidine-rich Insulin mRNA 3′-Untranslated Region , 2002, Molecular medicine.

[38]  N. Welsh,et al.  Control of Insulin mRNA Stability in Rat Pancreatic Islets , 2002, The Journal of Biological Chemistry.

[39]  T. Tuschl,et al.  Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells , 2001, Nature.

[40]  G. Fuller,et al.  Fibroblast growth factor receptor-1 alpha-exon exclusion and polypyrimidine tract-binding protein in glioblastoma multiforme tumors. , 2000, Cancer research.

[41]  T. Kress,et al.  A Xenopus protein related to hnRNP I has a role in cytoplasmic RNA localization. , 1999, Molecular cell.

[42]  S. Byers,et al.  Cadherin-11 is expressed in invasive breast cancer cell lines. , 1999, Cancer research.

[43]  P. Yaswen,et al.  Gradual phenotypic conversion associated with immortalization of cultured human mammary epithelial cells. , 1997, Molecular biology of the cell.

[44]  David G Huntsman,et al.  Molecular pathology of cancer , 1997, British Journal of Cancer.

[45]  J. G. Patton,et al.  Characterization and molecular cloning of polypyrimidine tract-binding protein: a component of a complex necessary for pre-mRNA splicing. , 1991, Genes & development.

[46]  M. Stampfer,et al.  Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[47]  S. L. Hammond,et al.  Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[48]  O. Warburg [Origin of cancer cells]. , 1956, Oncologia.