Suppression of the Ewing’s sarcoma phenotype by FLI1/ERF repressor hybrids
暂无分享,去创建一个
[1] P. Sorensen,et al. Repression of the gene encoding the TGF-β type II receptor is a major target of the EWS-FLI1 oncoprotein , 1999, Nature Genetics.
[2] M. Roussel,et al. Transforming activity of EWS/FLI is not strictly dependent upon DNA-binding activity , 1999, Oncogene.
[3] C. Denny,et al. Divergent Ewing's sarcoma EWS/ETS fusions confer a common tumorigenic phenotype on NIH3T3 cells , 1999, Oncogene.
[4] H. Kovar,et al. Relation of neurological marker expression and EWS gene fusion types in MIC2/CD99-positive tumors of the Ewing family. , 1999, Human pathology.
[5] H. Kovar,et al. The Ewing family of tumors and the search for the Achilles' heel. , 1999, Current opinion in oncology.
[6] D. Sgouras,et al. Transcriptional Repressor ERF Is a Ras/Mitogen-Activated Protein Kinase Target That Regulates Cellular Proliferation , 1999, Molecular and Cellular Biology.
[7] P. Sorensen,et al. EWS-FLI1 and EWS-ERG gene fusions are associated with similar clinical phenotypes in Ewing's sarcoma. , 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[8] M. Ladanyi,et al. Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma. , 1999, Cancer research.
[9] S. Welford,et al. EWS/FLI1 up regulates mE2-C, a cyclin-selective ubiquitin conjugating enzyme involved in cyclin B destruction , 1998, Oncogene.
[10] H. Kovar,et al. Ewing's sarcoma and peripheral primitive neuroectodermal tumors after their genetic union. , 1998, Current opinion in oncology.
[11] B. Wasylyk,et al. Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway. , 1998, Trends in biochemical sciences.
[12] A. Nordheim,et al. Ets transcription factors and human disease. , 1998, Biochimica et biophysica acta.
[13] Olivier Delattre,et al. EWS, but Not EWS-FLI-1, Is Associated with Both TFIID and RNA Polymerase II: Interactions between Two Members of the TET Family, EWS and hTAFII68, and Subunits of TFIID and RNA Polymerase II Complexes , 1998, Molecular and Cellular Biology.
[14] R Berger,et al. A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia. , 1997, Science.
[15] A. E. Sippel,et al. DNA binding and transcriptional activation by the Ski oncoprotein mediated by interaction with NFI. , 1997, Nucleic acids research.
[16] P. Defossez,et al. Structure-function relationships of the PEA3 group of Ets-related transcription factors. , 1997, Biochemical and molecular medicine.
[17] Marcienne M Wright,et al. EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic , 1997, Nature Genetics.
[18] K. Tanaka,et al. EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells. , 1997, The Journal of clinical investigation.
[19] D. Blair,et al. Increased expression of the ETS-related transcription factor FLI-1/ERGB correlates with and can induce the megakaryocytic phenotype. , 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[20] H. Hurst. Transcription factors as drug targets in cancer. , 1996, European journal of cancer.
[21] P. Chambon,et al. hTAF(II)68, a novel RNA/ssDNA‐binding protein with homology to the pro‐oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II. , 1996, The EMBO journal.
[22] T. Golub,et al. Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia , 1996, Molecular and cellular biology.
[23] M. Schemper,et al. EWS/FLI-1 antagonists induce growth inhibition of Ewing tumor cells in vitro. , 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[24] J. Hata,et al. A novel chimera gene between EWS and E1A-F, encoding the adenovirus E1A enhancer-binding protein, in extraosseous Ewing's sarcoma. , 1996, Biochemical and biophysical research communications.
[25] A. Bernstein,et al. An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes , 1995, Molecular and cellular biology.
[26] R. J. Fisher,et al. ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets‐associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation. , 1995, The EMBO journal.
[27] M. Ouchida,et al. Loss of tumorigenicity of Ewing's sarcoma cells expressing antisense RNA to EWS-fusion transcripts. , 1995, Oncogene.
[28] G. Thomas,et al. Sensitive detection of occult Ewing's cells by the reverse transcriptase-polymerase chain reaction. , 1995, British Journal of Cancer.
[29] D C Ward,et al. Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[30] P. Riegman,et al. Translocation (12;22) (p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11. , 1995, Oncogene.
[31] C. Denny,et al. A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1. , 1995, Oncogene.
[32] R. Meadows,et al. Solution structure of the ets domain of Fli-1 when bound to DNA , 1994, Nature Structural Biology.
[33] R. Fisher,et al. Structural inferences of the ETS1 DNA-binding domain determined by mutational analysis. , 1994, Oncogene.
[34] P. Sorensen,et al. A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS–family transcription factor, ERG , 1994, Nature Genetics.
[35] C. Denny,et al. The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1 , 1993, Molecular and cellular biology.
[36] J. Testa,et al. The ERGB/Fli-1 gene: isolation and characterization of a new member of the family of human ETS transcription factors. , 1992, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[37] G. Thomas,et al. Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours , 1992, Nature.
[38] R. Fisher,et al. High-affinity DNA-protein interactions of the cellular ETS1 protein: the determination of the ETS binding motif. , 1991, Oncogene.
[39] A. Bernstein,et al. Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1. , 1991, Genes & development.
[40] B. Lewin. Oncogenic conversion by regulatory changes in transcription factors , 1991, Cell.
[41] J. Yee,et al. Factors affecting long-term stability of Moloney murine leukemia virus-based vectors. , 1989, Virology.
[42] R. Mulligan,et al. Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[43] A. Miller,et al. Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production , 1986, Molecular and cellular biology.
[44] C. Denny,et al. Biology of EWS/FLI and related fusion genes in Ewing's sarcoma and primitive neuroectodermal tumor. , 1997, Current topics in microbiology and immunology.
[45] M. Klemsz,et al. The ETS oncogene family in development, proliferation and neoplasia. , 1994, International journal of hematology.