Overexpression of erg20 gene encoding farnesyl pyrophosphate synthase has contrasting effects on activity of enzymes of the dolichyl and sterol branches of mevalonate pathway in Trichoderma reesei.

[1]  S. Baud,et al.  Function and Localization of the Arabidopsis thaliana Diacylglycerol Acyltransferase DGAT2 Expressed in Yeast , 2014, PloS one.

[2]  Jihong Jiang,et al.  Molecular characterization and expression analysis of a gene encoding for farnesyl diphosphate synthase from Euphorbia pekinensis Rupr , 2012, Molecular Biology Reports.

[3]  S. Gutiérrez,et al.  Overexpression of the Trichoderma brevicompactum tri5 Gene: Effect on the Expression of the Trichodermin Biosynthetic Genes and on Tomato Seedlings , 2011, Toxins.

[4]  R. Russell,et al.  Bisphosphonates: the first 40 years. , 2011, Bone.

[5]  Hironobu Nakayama,et al.  Growth defects resulting from inhibiting ERG20 and RAM2 in Candida glabrata. , 2011, FEMS microbiology letters.

[6]  D. Płochocka,et al.  Investigating the Effects of Statins on Cellular Lipid Metabolism Using a Yeast Expression System , 2009, PloS one.

[7]  Yi Ding,et al.  Molecular Cloning, Characterization, and Differential Expression of a Farnesyl-Diphosphate Synthase Gene from the Basidiomycetous Fungus Ganoderma lucidum , 2008, Bioscience, biotechnology, and biochemistry.

[8]  J. Vizcaíno,et al.  Partial silencing of a hydroxy-methylglutaryl-CoA reductase-encoding gene in Trichoderma harzianum CECT 2413 results in a lower level of resistance to lovastatin and lower antifungal activity. , 2007, Fungal genetics and biology : FG & B.

[9]  J. Kruszewska,et al.  Overexpression of the Saccharomyces cerevisiae RER2 gene in Trichoderma reesei affects dolichol dependent enzymes and protein glycosylation. , 2006, Fungal genetics and biology : FG & B.

[10]  J. Vizcaíno,et al.  Cloning and characterization of the erg1 gene of Trichoderma harzianum: effect of the erg1 silencing on ergosterol biosynthesis and resistance to terbinafine. , 2006, Fungal genetics and biology : FG & B.

[11]  A. Velayos,et al.  A novel fungal prenyl diphosphate synthase in the dimorphic zygomycete Mucor circinelloides , 2004, Current Genetics.

[12]  F. Karst,et al.  Farnesyl diphosphate synthase activity affects ergosterol level and proliferation of yeast Saccharomyces cerevisae , 2004, Cell biology international.

[13]  G. Palamarczyk,et al.  Dolichol biosynthesis in the yeast Saccharomyces cerevisiae: an insight into the regulatory role of farnesyl diphosphate synthase. , 2002, FEMS yeast research.

[14]  U. Thrane,et al.  Fast methods for screening of trichothecenes in fungal cultures using gas chromatography-tandem mass spectrometry. , 2001, Journal of chromatography. A.

[15]  F. Karst,et al.  The regulation of activity of main mevalonic acid pathway enzymes: farnesyl diphosphate synthase, 3-hydroxy-3-methylglutaryl-CoA reductase, and squalene synthase in yeast Saccharomyces cerevisiae. , 2000, Biochemical and biophysical research communications.

[16]  R. Gardner,et al.  A Highly Conserved Signal Controls Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) Reductase in Eukaryotes* , 1999, The Journal of Biological Chemistry.

[17]  C. Kubicek,et al.  Overexpression of the Saccharomyces cerevisiaeMannosylphosphodolichol Synthase-Encoding Gene in Trichoderma reesei Results in an Increased Level of Protein Secretion and Abnormal Cell Ultrastructure , 1999, Applied and Environmental Microbiology.

[18]  F. Karst,et al.  Effect of squalene synthase gene disruption on synthesis of polyprenols in Saccharomyces cerevisiae , 1998, FEBS letters.

[19]  Thomas L. Madden,et al.  Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. , 1997, Nucleic acids research.

[20]  F. Karst,et al.  Polyprenol formation in the yeast Saccharomyces cerevisiae: effect of farnesyl diphosphate synthase overexpression. , 1997, Journal of lipid research.

[21]  B. Tudzynski,et al.  The isoprenoid pathway: cloning and characterization of fungal FPPS genes , 1996, Current Genetics.

[22]  W. Kang,et al.  Cloning and analysis of a cDNA encoding farnesyl diphosphate synthase from Artemisia annua. , 1996, Gene.

[23]  J. Rine,et al.  The biology of HMG-CoA reductase: the pros of contra-regulation. , 1996, Trends in biochemical sciences.

[24]  F. Karst,et al.  Arabidopsis thaliana Contains Two Differentially Expressed Farnesyl-Diphosphate Synthase Genes (*) , 1996, The Journal of Biological Chemistry.

[25]  F. Karst,et al.  Cloning of an Arabidopsis thaliana cDNA coding for farnesyl diphosphate synthase by functional complementation in yeast , 1994, Plant Molecular Biology.

[26]  I. Shechter,et al.  Solubilization, purification, and characterization of a truncated form of rat hepatic squalene synthetase. , 1992, The Journal of biological chemistry.

[27]  J. Visser,et al.  The development of a heterologous transformation system for the cellulolytic fungus Trichoderma reesei based on a pyrG-negative mutant strain , 1990, Current Genetics.

[28]  F. Karst,et al.  Isolation and properties of yeast mutants affected in farnesyl diphosphate synthetase , 1990, Current Genetics.

[29]  J. Goldstein,et al.  Regulation of the mevalonate pathway , 1990, Nature.

[30]  C. Poulter,et al.  Farnesyl diphosphate synthetase. Molecular cloning, sequence, and expression of an essential gene from Saccharomyces cerevisiae. , 1989, The Journal of biological chemistry.

[31]  K. Svenson,et al.  Molecular Cloning and Sequence of a Cholesterol-Repressible Enzyme Related to Prenyltransferase in the Isoprene Biosynthetic Pathway , 1987, Molecular and cellular biology.

[32]  P. Chomczyński,et al.  Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. , 1987, Analytical biochemistry.

[33]  F. Karst,et al.  Regulation of early enzymes of ergosterol biosynthesis in Saccharomyces cerevisiae. , 1986, The Biochemical journal.

[34]  M. Brown,et al.  Synthesis of delta 2-isopentenyl tRNA from mevalonate in cultured human fibroblasts. , 1980, The Journal of biological chemistry.

[35]  N. Eberhardt,et al.  Prenyltransferase from Saccharomyces cerevisiae. Purification to homogeneity and molecular properties. , 1975, The Journal of biological chemistry.

[36]  Oliver H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.

[37]  T. Kuo,et al.  One-step transformation of yeast in stationary phase , 2004, Current Genetics.

[38]  J. Goldstein,et al.  Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain. , 2003, Molecular cell.

[39]  F. Sherman.  Getting started with yeast. , 1991, Methods in enzymology.

[40]  C. Yanisch-Perron,et al.  Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. , 1985, Gene.

[41]  T. Jukes.  CHAPTER 24 – Evolution of Protein Molecules , 1969 .