Growth hormone in the tumor microenvironment
暂无分享,去创建一个
[1] J. Kopchick,et al. The effects of growth hormone on therapy resistance in cancer , 2019, Cancer drug resistance.
[2] S. Melmed,et al. Growth Hormone Induces Colon DNA Damage Independent of IGF-1. , 2019, Endocrinology.
[3] A. Bartke,et al. Growth Hormone Deficiency: Health and Longevity. , 2018, Endocrine reviews.
[4] S. Melmed,et al. Excess growth hormone suppresses DNA damage repair in epithelial cells. , 2019, JCI insight.
[5] R. Raychowdhury,et al. Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation , 2019, Aging cell.
[6] G. David,et al. Pro- and anti-tumorigenic functions of the senescence-associated secretory phenotype , 2019, Expert opinion on therapeutic targets.
[7] C. Boguszewski,et al. Growth Hormone's Links to Cancer. , 2018, Endocrine reviews.
[8] Susan A. Cole,et al. Field , 2018, The Body Wars.
[9] H. Sørensen,et al. Cancer Incidence in Patients With Acromegaly: A Cohort Study and Meta-Analysis of the Literature , 2018, The Journal of clinical endocrinology and metabolism.
[10] Wei Sha,et al. Inhibition of experimental small‐cell and non‐small‐cell lung cancers by novel antagonists of growth hormone‐releasing hormone , 2018, International journal of cancer.
[11] J. Kopchick,et al. MECHANISMS IN ENDOCRINOLOGY: Lessons from growth hormone receptor gene-disrupted mice: are there benefits of endocrine defects? , 2018, European journal of endocrinology.
[12] D. Bernard,et al. Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence , 2018, Cell Death & Disease.
[13] T. Graham,et al. An evolutionary perspective on field cancerization , 2017, Nature Reviews Cancer.
[14] T. Zhu,et al. Autocrine hGH stimulates oncogenicity, epithelial-mesenchymal transition and cancer stem cell-like behavior in human colorectal carcinoma , 2017, Oncotarget.
[15] J. Kopchick,et al. Growth Hormone and the Epithelial-to-Mesenchymal Transition , 2017, The Journal of clinical endocrinology and metabolism.
[16] T. Zhu,et al. Tumour-Derived Human Growth Hormone As a Therapeutic Target in Oncology , 2017, Trends in Endocrinology & Metabolism.
[17] E. Sahai,et al. Tumor Microenvironment and Differential Responses to Therapy. , 2017, Cold Spring Harbor perspectives in medicine.
[18] T. Zhu,et al. Autocrine Human Growth Hormone Promotes Invasive and Cancer Stem Cell-Like Behavior of Hepatocellular Carcinoma Cells by STAT3 Dependent Inhibition of CLAUDIN-1 Expression , 2017, International journal of molecular sciences.
[19] Shiyong Wu,et al. Growth Hormone Receptor Knockdown Sensitizes Human Melanoma Cells to Chemotherapy by Attenuating Expression of ABC Drug Efflux Pumps , 2017, Hormones and Cancer.
[20] Wei Xiong,et al. Role of tumor microenvironment in tumorigenesis , 2017, Journal of Cancer.
[21] Shiyong Wu,et al. Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways , 2017, Oncotarget.
[22] J. Jackson,et al. SASP: Tumor Suppressor or Promoter? Yes! , 2016, Trends in cancer.
[23] Giovanni Simone,et al. Angiogenesis and Antiangiogenesis in Triple-Negative Breast cancer1 , 2016, Translational oncology.
[24] E. Vilain,et al. WNT4 mediates the autocrine effects of growth hormone in mammary carcinoma cells. , 2016, Endocrine-related cancer.
[25] S. Melmed,et al. Growth hormone is permissive for neoplastic colon growth , 2016, Proceedings of the National Academy of Sciences.
[26] Yuchen Jiang,et al. Role of the tumor microenvironment in tumor progression and the clinical applications (Review). , 2016, Oncology reports.
[27] Björn Schumacher,et al. p53 in the DNA-Damage-Repair Process. , 2016, Cold Spring Harbor perspectives in medicine.
[28] M. Zhang,et al. Human growth hormone and human prolactin function as autocrine/paracrine promoters of progression of hepatocellular carcinoma , 2016, Oncotarget.
[29] A. Lam,et al. Immune Cell Infiltrates in Pituitary Adenomas: More Macrophages in Larger Adenomas and More T Cells in Growth Hormone Adenomas , 2015, Endocrine Pathology.
[30] A. Khanna. DNA damage in cancer therapeutics: a boon or a curse? , 2015, Cancer research.
[31] M. Zhang,et al. Autocrine/Paracrine Human Growth Hormone-stimulated MicroRNA 96-182-183 Cluster Promotes Epithelial-Mesenchymal Transition and Invasion in Breast Cancer* , 2015, The Journal of Biological Chemistry.
[32] Laurent Beaugerie,et al. Cancers complicating inflammatory bowel disease. , 2015, The New England journal of medicine.
[33] R. Subramani,et al. Growth hormone receptor inhibition decreases the growth and metastasis of pancreatic ductal adenocarcinoma , 2014, Experimental & Molecular Medicine.
[34] O. O. Gul,et al. Investigation of genotoxicity in acromegaly from peripheral blood lymphocyte cultures using a micronucleus assay. , 2014, The Journal of clinical endocrinology and metabolism.
[35] V. Tillmann,et al. Translational Neuroendocrinology: Control of Human Growth , 2014, Journal of neuroendocrinology.
[36] D. Chia. Minireview: mechanisms of growth hormone-mediated gene regulation. , 2014, Molecular endocrinology.
[37] B. Rini,et al. Angiogenesis and the tumor microenvironment: vascular endothelial growth factor and beyond. , 2014, Seminars in oncology.
[38] G. Baskol,et al. Increased genome instability and oxidative DNA damage and their association with IGF-1 levels in patients with active acromegaly. , 2014, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
[39] P. Adams,et al. Senescence at a glance , 2013, Journal of Cell Science.
[40] S. Melmed,et al. Growth hormone is a cellular senescence target in pituitary and nonpituitary cells , 2013, Proceedings of the National Academy of Sciences.
[41] J. Kopchick,et al. The GH/IGF-1 axis in ageing and longevity , 2013, Nature Reviews Endocrinology.
[42] C. Carter-Su,et al. Phosphorylation of the adaptor protein SH2B1&bgr; regulates its ability to enhance growth hormone-dependent macrophage motility , 2013, Journal of Cell Science.
[43] A. Bartke,et al. Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone , 2013, Cell cycle.
[44] A. Noel,et al. Targeting the tumor microenvironment for cancer therapy. , 2013, Clinical chemistry.
[45] Nicola J. Curtin,et al. DNA repair dysregulation from cancer driver to therapeutic target , 2012, Nature Reviews Cancer.
[46] T. Hagemann,et al. The tumor microenvironment at a glance , 2012, Journal of Cell Science.
[47] T. Zhu,et al. Autocrine human GH promotes radioresistance in mammary and endometrial carcinoma cells. , 2012, Endocrine-related cancer.
[48] T. Graham,et al. Field cancerization in the intestinal epithelium of patients with Crohn's ileocolitis. , 2012, Gastroenterology.
[49] D. Sabatini,et al. mTOR Signaling in Growth Control and Disease , 2012, Cell.
[50] D. Molè,et al. Growth hormone receptor blockade inhibits growth hormone-induced chemoresistance by restoring cytotoxic-induced apoptosis in breast cancer cells independently of estrogen receptor expression. , 2012, The Journal of clinical endocrinology and metabolism.
[51] M. Waters,et al. Growth hormone and cell growth. , 2012, Endocrine development.
[52] Helen H. W. Chen,et al. Autocrine human growth hormone reduces mammary and endometrial carcinoma cell sensitivity to mitomycin C. , 2011, Oncology reports.
[53] D. Lyden,et al. The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts. , 2011, Seminars in cancer biology.
[54] J. Carlson. Faculty of 1000 evaluation for Fields and field cancerization: the preneoplastic origins of cancer: asymptomatic hyperplastic fields are precursors of neoplasia, and their progression to tumors can be tracked by saturation density in culture. , 2011 .
[55] D. Hanahan,et al. Hallmarks of Cancer: The Next Generation , 2011, Cell.
[56] M. Bronner,et al. Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation. , 2011, Cancer research.
[57] J. Campisi,et al. Four faces of cellular senescence , 2011, The Journal of cell biology.
[58] C. Gialeli,et al. Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting , 2011, The FEBS journal.
[59] M. Waters,et al. The growth hormone receptor: mechanism of activation and clinical implications , 2010, Nature Reviews Endocrinology.
[60] Z. Werb,et al. Tumors as organs: complex tissues that interface with the entire organism. , 2010, Developmental cell.
[61] J. Campisi,et al. The senescence-associated secretory phenotype: the dark side of tumor suppression. , 2010, Annual review of pathology.
[62] S. Melmed. Acromegaly pathogenesis and treatment. , 2009, The Journal of clinical investigation.
[63] D. Molè,et al. Growth hormone excess promotes breast cancer chemoresistance. , 2009, The Journal of clinical endocrinology and metabolism.
[64] G. Nelson,et al. DNA damage response and cellular senescence in tissues of aging mice , 2009, Aging cell.
[65] J. Campisi,et al. Persistent DNA damage signaling triggers senescence-associated inflammatory cytokine secretion , 2009, Nature Cell Biology.
[66] R. Weinberg,et al. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits , 2009, Nature Reviews Cancer.
[67] C. Print,et al. Autocrine human growth hormone promotes tumor angiogenesis in mammary carcinoma. , 2009, Endocrinology.
[68] Adrian V. Lee,et al. Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions. , 2009, Endocrine reviews.
[69] Donald J. Johann,et al. Cancer and the tumor microenvironment: a review of an essential relationship , 2009, Cancer Chemotherapy and Pharmacology.
[70] F. D. D. Fagagna. Living on a break: cellular senescence as a DNA-damage response , 2008, Nature Reviews Cancer.
[71] R. Hakem,et al. DNA‐damage repair; the good, the bad, and the ugly , 2008, The EMBO journal.
[72] K. M. Mohankumar,et al. The Contribution of Growth Hormone to Mammary Neoplasia , 2008, Journal of Mammary Gland Biology and Neoplasia.
[73] P. Singal,et al. Growth hormone in vascular pathology: neovascularization and expression of receptors is associated with cellular proliferation. , 2007, Anticancer research.
[74] M. Waters,et al. Nuclear targeting of the growth hormone receptor results in dysregulation of cell proliferation and tumorigenesis , 2007, Proceedings of the National Academy of Sciences.
[75] C. Carter-Su,et al. Recent advances in growth hormone signaling , 2007, Reviews in Endocrine and Metabolic Disorders.
[76] J. Iñiguez-Lluhí,et al. Multiple mechanisms of growth hormone-regulated gene transcription. , 2007, Molecular genetics and metabolism.
[77] R. Kanaar,et al. DNA double-strand break repair: all's well that ends well. , 2006, Annual review of genetics.
[78] M. Lavin,et al. Involvement of novel autophosphorylation sites in ATM activation , 2006, The EMBO journal.
[79] K. Kovitz,et al. The expression of the pituitary growth hormone-releasing hormone receptor and its splice variants in normal and neoplastic human tissues. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[80] P. Gluckman,et al. Gene Expression Profiling to Identify Oncogenic Determinants of Autocrine Human Growth Hormone in Human Mammary Carcinoma* , 2005, Journal of Biological Chemistry.
[81] Stephen P. Jackson,et al. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage , 2005, Nature.
[82] C. Kenyon. The Plasticity of Aging: Insights from Long-Lived Mutants , 2005, Cell.
[83] R. Wanke,et al. Accelerated growth and visceral lesions in transgenic mice expressing foreign genes of the growth hormone family: an overview , 1991, Pediatric Nephrology.
[84] Yoshio Miki,et al. Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage , 2004, Cancer science.
[85] P. Gluckman,et al. Phenotypic conversion of human mammary carcinoma cells by autocrine human growth hormone. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[86] J. Barrett,et al. Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks , 2004, Nature Cell Biology.
[87] C. R. Leemans,et al. A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implications. , 2003, Cancer research.
[88] M. Waters,et al. Growth hormone and colorectal carcinoma: localization of receptors. , 2000, In vivo.
[89] G. Morel,et al. Autocrine stimulation of human mammary carcinoma cell proliferation by human growth hormone. , 1999, Experimental cell research.
[90] L. Ellis,et al. Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I. , 1998, Cancer research.
[91] M. Waters,et al. Cellular expression of growth hormone and prolactin receptors in human breast disorders , 1998, International journal of cancer.
[92] D. Donner,et al. Induction of Vascular Endothelial Growth Factor by Insulin-like Growth Factor 1 in Colorectal Carcinoma* , 1996, The Journal of Biological Chemistry.
[93] C. Wiedermann,et al. Stimulation of monocyte chemotaxis by human growth hormone and its deactivation by somatostatin. , 1993, Blood.
[94] O. Isaksson,et al. Induction of mammary adenocarcinomas in metallothionein promoter‐human growth hormone transgenic mice , 1991, International journal of cancer.
[95] M. Brandon,et al. The expression of a metallothionein-ovine growth hormone fusion gene in transgenic mice does not impair fertility but results in pathological lesions in the liver. , 1989, Endocrinology.
[96] D. Slaughter,et al. “Field cancerization” in oral stratified squamous epithelium. Clinical implications of multicentric origin , 1953, Cancer.