Inhibition of constitutively active Jak-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells

[1]  Yuetsu Tanaka,et al.  Curcumin (diferuloylmethane) inhibits constitutive active NF-kappaB, leading to suppression of cell growth of human T-cell leukemia virus type I-infected T-cell lines and primary adult T-cell leukemia cells. , 2006, International journal of cancer.

[2]  Yuetsu Tanaka,et al.  Inhibition of constitutively active Jak-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells , 2006, Retrovirology.

[3]  M. Hatano,et al.  Transcriptional activation of survivin through the NF‐κB pathway by human T‐cell leukemia virus type I tax , 2005, International journal of cancer.

[4]  Daniela S Krause,et al.  Tyrosine kinases as targets for cancer therapy. , 2005, The New England journal of medicine.

[5]  M. Matsuoka.  Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL) , 2005, Retrovirology.

[6]  R. Jove,et al.  Roscovitine inhibits STAT5 activity and induces apoptosis in the human leukemia virus type 1-transformed cell line MT-2. , 2003, Cancer research.

[7]  G. Feldman,et al.  Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma. , 2003, Blood.

[8]  K. Yamaguchi,et al.  5′-Long Terminal Repeat-Selective CpG Methylation of Latent Human T-Cell Leukemia Virus Type 1 Provirus In Vitro and In Vivo , 2002, Journal of Virology.

[9]  M. Tomonaga,et al.  Bay 11-7082 inhibits transcription factor NF-kappaB and induces apoptosis of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cells. , 2002, Blood.

[10]  F. Kashanchi,et al.  Activation of cyclin D1 and D2 promoters by human T‐cell leukemia virus type I tax protein is associated with IL‐2–independent growth of T cells , 2002, International journal of cancer.

[11]  P. Koskinen,et al.  Cutting Edge: Transcriptional Activity of NFATc1 Is Enhanced by the Pim-1 Kinase1 , 2002, The Journal of Immunology.

[12]  M. Tomonaga,et al.  A new G‐CSF‐supported combination chemotherapy, LSG15, for adult T‐cell leukaemia‐lymphoma: Japan Clinical Oncology Group Study 9303 , 2001, British journal of haematology.

[13]  K. Ohtani,et al.  Direct trans-activation of the human cyclin D2 gene by the oncogene product Tax of human T-cell leukemia virus type I , 2001, Oncogene.

[14]  岩永 律子.  Molecular mechanism of cell cycle progression induced by the oncogene product Tax of human T-cell leukemia virus type 1 , 2001 .

[15]  H. Rui,et al.  Functional Uncoupling of the Janus Kinase 3-Stat5 Pathway in Malignant Growth of Human T Cell Leukemia Virus Type 1-Transformed Human T Cells1 , 2000, The Journal of Immunology.

[16]  M. Tomonaga,et al.  Constitutive activation of transcription factor AP-1 in primary adult T-cell leukemia cells. , 2000, Blood.

[17]  K. Tarte,et al.  JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen‐activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells , 2000, British journal of haematology.

[18]  Roy Garcia,et al.  STATs in oncogenesis , 2000, Oncogene.

[19]  P. Coffer,et al.  The role of STATs in myeloid differentiation and leukemia , 2000, Oncogene.

[20]  Thomas S. Lin,et al.  STAT signaling in the pathogenesis and treatment of leukemias , 2000, Oncogene.

[21]  A. Hida,et al.  Inhibition of Caspase Cascade by HTLV-I Tax Through Induction of NF-κB Nuclear Translocation , 1999 .

[22]  M. Kannagi,et al.  Human T-cell leukemia virus type 1 Tax protein induces the expression of STAT1 and STAT5 genes in T-cells , 1999, Oncogene.

[23]  M. Tomonaga,et al.  Constitutive Activation of NF-κB in Primary Adult T-Cell Leukemia Cells , 1999 .

[24]  W. Farrar,et al.  JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response. , 1999, Journal of immunology.

[25]  E. Butcher,et al.  Inhibition of experimental autoimmune encephalomyelitis by a tyrosine kinase inhibitor. , 1999, Journal of immunology.

[26]  T. Hirano,et al.  Stat3 Is Required for the Gp130-mediated Full Activation of the C-myc Gene , 1999 .

[27]  D. Buckley,et al.  Prolactin regulation of pim-1 expression: positive and negative promoter elements. , 1999, Endocrinology.

[28]  W. Leonard,et al.  Human and Simian T-Cell Leukemia Viruses Type 2 (HTLV-2 and STLV-2pan-p) Transform T Cells Independently of Jak/STAT Activation , 1998, Journal of Virology.

[29]  T. Waldmann,et al.  Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[30]  J. Darnell.  STATs and gene regulation. , 1997, Science.

[31]  M. Ishiyama,et al.  A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet. , 1996, Biological & pharmaceutical bulletin.

[32]  D. Beach,et al.  Cdc25 cell-cycle phosphatase as a target of c-myc , 1996, Nature.

[33]  N. Mori,et al.  Transactivation of the interleukin-1alpha promoter by human T-cell leukemia virus type I and type II Tax proteins. , 1996, Blood.

[34]  A. Levitzki,et al.  Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor , 1996, Nature.

[35]  G. Franchini.  Molecular mechanisms of human T-cell leukemia/lymphotropic virus type I infection. , 1995, Blood.

[36]  W. Leonard,et al.  Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I. , 1995, Science.

[37]  J. Darnell,et al.  Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. , 1995, Annual review of biochemistry.

[38]  Yuetsu Tanaka,et al.  Generation and characterization of monoclonal antibodies against multiple epitopes on the C‐terminal half of envelope gp46 of human T‐cell leukemia virus type‐I (HTLV‐I) , 1990, International journal of cancer.

[39]  Yuetsu Tanaka,et al.  Heterogeneity of Antigen Molecules Recognized by Anti‐tax1 Monoclonal Antibody Lt‐4 in Cell Lines Bearing Human T Cell Leukemia Virus Type I and Related Retroviruses , 1990, Japanese journal of cancer research : Gann.

[40]  K. Tajima.  The 4th nation‐wide study of adult T‐cell leukemia/lymphoma (ATL) in Japan: Estimates of risk of ATL and its geographical and clinical features , 1990, International journal of cancer.

[41]  K. Sugamura,et al.  Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat , 1989, Journal of virology.

[42]  Yuetsu Tanaka,et al.  Antigens related to three core proteins of HTLV‐I (p24, p19 and p15) and their intracellular localizations, as defined by monoclonal antibodies , 1986, International journal of cancer.

[43]  T. Honjo,et al.  Origin of human T-lymphotrophic virus I-positive T cell lines in adult T cell leukemia. Analysis of T cell receptor gene rearrangement , 1985, The Journal of experimental medicine.

[44]  M. Yoshida,et al.  Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[45]  Y. Ohtsuki,et al.  Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cells , 1981, Nature.

[46]  John D. Minna,et al.  Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma , 1980, Proceedings of the National Academy of Sciences.

[47]  H. Towler,et al.  Adult T-cell leukemia : antigen in an ATL cell line and detection of antibodies to the antigen in human sera , 2022 .