Sensory neuropathy and anti‐Hu antibodies in a patient with seminoma

A man with subacute sensory ncuronopathy (SSN) had a stage 1 seminoma. His serum and cerebrospinal fluid (CSF) contained anti‐Hu antibodies (type 1 anti‐neuronal nuclear antibodies, ANNA‐1). Following orchidectomy, radiotherapy, prednisolone, plasma exchange and intravenous immunoglobulin the antineuronal antibody titre fell and the neuropathy improved.

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