Acoustic feedback for hyperthermia phased-array applicators: aberration correction, motion compensation and multiple focusing in the presence of tissue inhomogeneities

When used in conjunction with ultrasound phased-array applicators, complex pressure measurements using miniature needle hydrophone arrays will allow optimal focusing through tissue inhomogeneities (aberration correction) and compensation for patient movement in real time. Experimental results using needle hydrophone measurements in a water tank with thick fatty tissue aberrater are presented to provide a proof of concept. The fabrication of silicon-based needle hydrophone arrays which will be used to provide acoustic feedback during hyperthermia treatments has been initiated.<<ETX>>

[1]  P. Corry,et al.  Human Cancer Treatment with Ultrasound , 1984, IEEE Transactions on Sonics and Ultrasonics.

[2]  M. O'Donnell,et al.  Phase-aberration correction using signals from point reflectors and diffuse scatterers: measurements , 1988, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[3]  C.A. Cain,et al.  A cylindrical-section ultrasound phased-array applicator for hyperthermia cancer therapy , 1988, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[4]  C.A. Cain,et al.  Multiple-focus ultrasound phased-array pattern synthesis: optimal driving-signal distributions for hyperthermia , 1989, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[5]  E. Ebbini,et al.  Deep localized hyperthermia with ultrasound-phased arrays using the pseudoinverse pattern synthesis method , 1990 .

[6]  S.W. Smith,et al.  Experimental results with a real-time adaptive ultrasonic imaging system for viewing through distorting media , 1990, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[7]  C.A. Cain,et al.  Computationally efficient algorithms for control of ultrasound phased-array hyperthermia applicators based on a pseudoinverse method , 1990, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[8]  C. Cain,et al.  Experimental evaluation of a prototype cylindrical section ultrasound hyperthermia phased-array applicator , 1991, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.