Clinical Pathway Analytics

Recently, medical informatics researchers have focused on supporting standardized activity coordination patterns that structure complex multi-disciplinary interventions. While the designed clinical pathways are aimed to improve the provided healthcare, this paper demonstrates that the care process of individual patients can significantly deviate from the standardized path. Examining the deviations in the individual care processes might result in the further enhancement of the provided quality of care, the evaluation of adverse events or the identification of suboptimal use of resources. This paper presents an optimal combination of process analytics for extracting valuable medical and organizational information from real-world care processes. The authors elaborate an extensive case study based on these process analytics on a series of oncological care processes.

[1]  Koen Vanhoof,et al.  A business process mining application for internal transaction fraud mitigation , 2011, Expert Syst. Appl..

[2]  Kim M. Unertl,et al.  Research Paper: Describing and Modeling Workflow and Information Flow in Chronic Disease Care , 2009, J. Am. Medical Informatics Assoc..

[3]  Kim M. Unertl,et al.  Health information exchange technology on the front lines of healthcare: workflow factors and patterns of use , 2011, J. Am. Medical Informatics Assoc..

[4]  Kai Zheng,et al.  Quantifying the impact of health IT implementations on clinical workflow: a new methodological perspective , 2010, J. Am. Medical Informatics Assoc..

[5]  Maurice van Keulen,et al.  Process Prediction in Noisy Data Sets: A Case Study in a Dutch Hospital , 2012, SIMPDA.

[6]  Andrew G. Lee,et al.  A Practice Pathway for the Initial Diagnostic Evaluation of Isolated Sixth Cranial Nerve Palsies , 1999, Medical decision making : an international journal of the Society for Medical Decision Making.

[7]  Wil M. P. van der Aalst,et al.  Conformance checking of processes based on monitoring real behavior , 2008, Inf. Syst..

[8]  Karen Beckman Pace,et al.  Barriers to successful implementation of a clinical pathway for CHF. , 2002, Journal for healthcare quality : official publication of the National Association for Healthcare Quality.

[9]  Thomas Rotter,et al.  Clinical pathways: effects on professional practice, patient outcomes, length of stay and hospital costs. , 2010, The Cochrane database of systematic reviews.

[10]  Jonas Poelmans,et al.  Combining Business Process and Data Discovery Techniques for Analyzing and Improving Integrated Care Pathways , 2010, ICDM.

[11]  M. Ball An Overview of Total Medical Information Systems , 1971, Methods of Information in Medicine.

[12]  M. Schnabel,et al.  Improving pathway compliance and clinician performance by using information technology. , 2007, International journal of medical informatics.

[13]  Wil M. P. van der Aalst,et al.  Process diagnostics using trace alignment: Opportunities, issues, and challenges , 2012, Inf. Syst..

[14]  S. Rodenhuis,et al.  Phase I and pharmacologic study of the combination paclitaxel and carboplatin as first-line chemotherapy in stage III and IV ovarian cancer. , 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[15]  Wil M. P. van der Aalst,et al.  Semantic-Based Conformance Checking of Computer Interpretable Medical Guidelines , 2011, BIOSTEC.

[16]  Manfred Reichert,et al.  IT support for healthcare processes - premises, challenges, perspectives , 2007, Data Knowl. Eng..

[17]  Jeffrey E. Lee,et al.  Cost and Utilization Impact of a Clinical Pathway for Patients Undergoing Pancreaticoduodenectomy , 2000, Annals of Surgical Oncology.

[18]  Bart Baesens,et al.  Advanced Care-Flow Mining and Analysis , 2011, Business Process Management Workshops.

[19]  Peep F M Stalmeier,et al.  Adherence and Decision Aids , 2011, Medical decision making : an international journal of the Society for Medical Decision Making.

[20]  E. James,et al.  What is a clinical pathway? Development of a definition to inform the debate , 2010, BMC medicine.

[21]  Kris Vanhaecht,et al.  Have We Drawn the Wrong Conclusions About the Value of Care Pathways? Is a Cochrane Review Appropriate? , 2012, Evaluation & the health professions.

[22]  Wil M. P. van der Aalst,et al.  Application of Process Mining in Healthcare - A Case Study in a Dutch Hospital , 2008, BIOSTEC.

[23]  Boudewijn F. van Dongen,et al.  Process Mining and Verification of Properties: An Approach Based on Temporal Logic , 2005, OTM Conferences.

[24]  Haider Mahdi,et al.  Clinical trials and progress with paclitaxel in ovarian cancer , 2010, International journal of women's health.

[25]  D. Berger,et al.  Shortened length of stay and hospital cost reduction with implementation of an accelerated clinical care pathway after elective colon resection. , 2003, Surgery.

[26]  S. Arikian,et al.  Analysis of the cost-effectiveness of paclitaxel as alternative combination therapy for advanced ovarian cancer. , 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[27]  Heikki Korvenranta,et al.  Internet based patient pathway as an educational tool for breast cancer patients , 2012, Int. J. Medical Informatics.

[28]  H. Kehlet,et al.  A clinical pathway to accelerate recovery after colonic resection. , 2000, Annals of surgery.

[29]  Bart Baesens,et al.  Comprehensive rule-based compliance checking and risk management with process mining , 2013, Decis. Support Syst..

[30]  Jeffrey Bell,et al.  Randomized phase III trial of three versus six cycles of adjuvant carboplatin and paclitaxel in early stage epithelial ovarian carcinoma: a Gynecologic Oncology Group study. , 2006, Gynecologic oncology.

[31]  Lei Huang,et al.  Acquiring logistics process intelligence: Methodology and an application for a Chinese bulk port , 2014, Expert Syst. Appl..

[32]  E. Moore,et al.  Evolution of a Multidisciplinary Clinical Pathway for the Management of Unstable Patients With Pelvic Fractures , 2001, Annals of surgery.

[33]  Kris Vanhaecht,et al.  Care Pathways are defined as complex interventions , 2010 .

[34]  Zhibin Jiang,et al.  An ontology-based hierarchical semantic modeling approach to clinical pathway workflows , 2009, Comput. Biol. Medicine.