Cytochrome P4503A (CYP3A) metabolism: Prediction ofIn Vivo activity in humans
暂无分享,去创建一个
[1] B. Ring,et al. The human drug metabolizing cytochromes P450 , 1996, Journal of Pharmacokinetics and Biopharmaceutics.
[2] F. Guengerich,et al. In Vitro techniques for studying drug metabolism , 1996, Journal of Pharmacokinetics and Biopharmaceutics.
[3] D. Shen,et al. Oral first‐pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A‐mediated metabolism , 1996, Clinical pharmacology and therapeutics.
[4] F. Aweeka,et al. The Use of Therapeutic Drug Monitoring to Optimise Immunosuppressive Therapy , 1996, Clinical pharmacokinetics.
[5] M Rowland,et al. Differentiation of absorption and first‐pass gut and hepatic metabolism in humans: Studies with cyclosporine , 1995, Clinical pharmacology and therapeutics.
[6] A. Renwick,et al. Ethnic differences in nifedipine kinetics: comparisons between Nigerians, Caucasians and South Asians. , 1995, British journal of clinical pharmacology.
[7] S. Krähenbühl,et al. Interaction between grapefruit juice and midazolam in humans , 1995, Clinical pharmacology and therapeutics.
[8] A. Guillouzo,et al. Report on the international workshop on the use of human in vitro liver preparations to study drug metabolism in drug development. Held at Utrecht, The Netherlands, 6-8 September 1994. , 1995 .
[9] M. Ducharme,et al. Disposition of intravenous and oral cyclosporine after administration with grapefruit juice , 1995, Clinical pharmacology and therapeutics.
[10] A. D. Rodrigues,et al. Use of in vitro human metabolism studies in drug development. An industrial perspective. , 1994, Biochemical pharmacology.
[11] P. Watkins. Noninvasive tests of CYP3A enzymes. , 1994, Pharmacogenetics.
[12] D. Bailey,et al. Grapefruit Juice and Drugs , 1994, Clinical pharmacokinetics.
[13] D. Wortham,et al. Itraconazole Affects Single‐Dose Terfenadine Pharmacokinetics and Cardiac Repolarization Pharmacodynamics , 1993, Journal of clinical pharmacology.
[14] D. Wortham,et al. The effect of fluconazole on the steady‐state pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine in humans , 1993, Clinical pharmacology and therapeutics.
[15] R Temple,et al. Understanding consequences of concurrent therapies. , 1993, JAMA.
[16] D. Wortham,et al. Terfenadine-ketoconazole interaction. Pharmacokinetic and electrocardiographic consequences. , 1993, JAMA.
[17] Y Chen,et al. Mechanism of the cardiotoxic actions of terfenadine. , 1993, JAMA.
[18] F. Flores-Murrieta,et al. Pharmacokinetics of Oral Nifedipine in Different Populations , 1993, Journal of clinical pharmacology.
[19] R. Woosley,et al. Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin , 1992, Clinical pharmacology and therapeutics.
[20] E. Schuetz,et al. Expression of cytochrome P450 3A in amphibian, rat, and human kidney. , 1992, Archives of biochemistry and biophysics.
[21] C. L. Ferguson,et al. Torsades de pointes occurring in association with terfenadine use. , 1990, JAMA.
[22] G. Yee,et al. Pharmacokinetic Drug Interactions with Cyclosporin (Part II) , 1990, Clinical pharmacokinetics.
[23] P. Maurel,et al. Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes. , 1990, Drug metabolism and disposition: the biological fate of chemicals.
[24] J. Derancourt,et al. Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily. , 1989, Drug metabolism and disposition: the biological fate of chemicals.
[25] T. Kronbach,et al. Cyclosporine metabolism in human liver: Identification of a cytochrome P‐450III gene family as the major cyclosporine‐metabolizing enzyme explains interactions of cyclosporine with other drugs , 1988, Clinical pharmacology and therapeutics.
[26] D. Weiner,et al. Bioavailability of terfenadine in man. , 1981, Biopharmaceutics & drug disposition.
[27] K. Detering,et al. Letter: Anti-epileptic drugs and failure of oral contraceptives. , 1974, Lancet.
[28] D. Reimers,et al. [The simultaneous use of rifampicin and other antitubercular agents with oral contraceptives]. , 1971, Praxis der Pneumologie.
[29] M. Viitasalo,et al. Itraconazole prevents terfenadine metabolism and increases risk of torsades de pointes ventricular tachycardia , 2004, European Journal of Clinical Pharmacology.
[30] D. Wortham,et al. Comparison of the Effect of the Macrolide Antibiotics Erythromycin, Clarithromycin and Azithromycin on Terfenadine Steady-State Pharmacokinetics and Electrocardiographic Parameters , 1994 .
[31] F. Guengerich,et al. Human cytochrome P-450 enzymes. , 1992, Life sciences.
[32] David W. Warnock,et al. Clinical Pharmacokinetics of Ketoconazole , 1988, Clinical pharmacokinetics.
[33] R. Hook,et al. Pharmacokinetics and biotransformation studies of terfenadine in man. , 1982, Arzneimittel-Forschung.