A branched chain amino acid metabolite drives vascular transport of fat and causes insulin resistance
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J. Rabinowitz | D. Forman | J. Baur | J. Rhee | A. Weljie | S. Lecker | Sungwhan F. Oh | D. Kasper | Mun Chun Chan | Cholsoon Jang | S. Parikh | A. Jiang | Z. Arany | G. Rowe | Ayon Ibrahim | S. Wada | Dennis L. Kasper | Saikumari Y. Krishnaiah | A. Hoshino | C. Ghosh | Laura X Liu | Boa Kim | Luisa G Baca | Esl Kim | Q. Chu | Laura X. Liu | Atsushi Hoshino | James Rhee | Shogo Wada
[1] Y. Kamei,et al. Metabolomic Analysis of the Skeletal Muscle of Mice Overexpressing PGC-1α , 2015, PloS one.
[2] M. Birnbaum,et al. Hepatic Insulin Signaling is Dispensable for Suppression of Glucose Output by Insulin in Vivo , 2015, Nature Communications.
[3] H. Daniel,et al. Metabolite profiling in plasma and tissues of ob/ob and db/db mice identifies novel markers of obesity and type 2 diabetes , 2015, Diabetologia.
[4] G. Shulman. Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic disease. , 2014, The New England journal of medicine.
[5] R. Arena,et al. Analysis of skeletal muscle gene expression patterns and the impact of functional capacity in patients with systolic heart failure. , 2014, Journal of cardiac failure.
[6] Mun Chun Chan,et al. The many roles of PGC-1α in muscle--recent developments. , 2014, Metabolism: clinical and experimental.
[7] F. Jaffer,et al. Endothelial PGC-1α mediates vascular dysfunction in diabetes. , 2014, Cell metabolism.
[8] Chad A. Cowan,et al. β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors. , 2014, Cell metabolism.
[9] P. Rustin,et al. Disconnecting mitochondrial content from respiratory chain capacity in PGC-1-deficient skeletal muscle. , 2013, Cell reports.
[10] C. Bertozzi,et al. Real-time noninvasive imaging of fatty acid uptake in vivo. , 2012, ACS chemical biology.
[11] Shoko Iwaki,et al. Vascular endothelial hyperpermeability induces the clinical symptoms of Clarkson disease (the systemic capillary leak syndrome). , 2012, Blood.
[12] C. Newgard. Interplay between lipids and branched-chain amino acids in development of insulin resistance. , 2012, Cell metabolism.
[13] V. Mootha,et al. Metabolite profiles and the risk of developing diabetes , 2011, Nature Medicine.
[14] S. Stone-Elander,et al. Vascular endothelial growth factor B controls endothelial fatty acid uptake , 2010, Nature.
[15] K. Ohlendieck,et al. Proteomic profiling of non-obese type 2 diabetic skeletal muscle. , 2010, International journal of molecular medicine.
[16] Svati H Shah,et al. A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. , 2009, Cell metabolism.
[17] Jiandie D. Lin,et al. Paradoxical effects of increased expression of PGC-1α on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism , 2008, Proceedings of the National Academy of Sciences.
[18] D. Kwiatkowski,et al. Regulation of Endothelial Nitric Oxide Synthase and Postnatal Angiogenesis by Rac1 , 2008, Circulation research.
[19] B. Spiegelman,et al. HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α , 2008, Nature.
[20] B. Spiegelman,et al. The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle. , 2007, Cell metabolism.
[21] B. Spiegelman,et al. Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. , 2006, Endocrine reviews.
[22] D. Darland,et al. TGFβ is required for the formation of capillary-like structures in three-dimensional cocultures of 10T1/2 and endothelial cells , 2004, Angiogenesis.
[23] Jiandie D. Lin,et al. Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres , 2002, Nature.
[24] Jiandie D. Lin,et al. Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. , 2002, Nature.
[25] M. Sasaki,et al. A severely brain-damaged case of 3-hydroxyisobutyric aciduria , 2001, Brain and Development.
[26] D. Darland,et al. TGF beta is required for the formation of capillary-like structures in three-dimensional cocultures of 10T1/2 and endothelial cells. , 2001, Angiogenesis.
[27] J. Greenwood,et al. Development and characterisation of a rat brain capillary endothelial culture: towards an in vitro blood-brain barrier. , 1992, Journal of cell science.
[28] A. Avogaro,et al. Contribution of 3-hydroxyisobutyrate to the measurement of 3-hydroxybutyrate in human plasma: comparison of enzymatic and gas-liquid chromatography-mass spectrometry assays in normal and in diabetic subjects. , 1989, Journal of lipid research.