Igs Expressed by Chronic Lymphocytic Leukemia B Cells Show Limited Binding-Site Structure Variability
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Anna Tramontano | Paolo Marcatili | Silvia Bruno | Anna Chailyan | Claudya Tenca | Fabio Ghiotto | Xiao-Jie Yan | A. Tramontano | Xiao-Jie Yan | N. Chiorazzi | S. Bruno | P. Marcatili | Anna Chailyan | M. Ferrarini | G. Cutrona | F. Ghiotto | C. Tenca | A. Mazzarello | D. Bagnara | F. Fais | F. Morabito | M. Colombo | Nicholas Chiorazzi | E. Albesiano | Emilia Albesiano | Giovanna Cutrona | Manlio Ferrarini | Franco Fais | Fortunato Morabito | Andrea N Mazzarello | Monica Colombo | Davide Bagnara | Monica Colombo
[1] Adam Godzik,et al. Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences , 2006, Bioinform..
[2] A Tramontano,et al. Antibody modeling: implications for engineering and design. , 2000, Methods.
[3] N. Chiorazzi,et al. Production of autoantibodies by CD5-expressing B lymphocytes from patients with chronic lymphocytic leukemia , 1989, The Journal of experimental medicine.
[4] Robert Sabatier,et al. IMGT standardized criteria for statistical analysis of immunoglobulin V‐REGION amino acid properties , 2004, Journal of molecular recognition : JMR.
[5] Xiao-Jie Yan,et al. From bloodjournal.hematologylibrary.org at PENN STATE UNIVERSITY on February 21, 2013. For personal use only. , 2007 .
[6] P. Rousseeuw. Silhouettes: a graphical aid to the interpretation and validation of cluster analysis , 1987 .
[7] Nikolaos Laoutaris,et al. Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations. , 2006, Blood.
[8] A Tramontano,et al. Framework residue 71 is a major determinant of the position and conformation of the second hypervariable region in the VH domains of immunoglobulins. , 1990, Journal of molecular biology.
[9] E. Meffre,et al. Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity. , 2005, The Journal of clinical investigation.
[10] A. Lesk,et al. Standard conformations for the canonical structures of immunoglobulins. , 1997, Journal of molecular biology.
[11] Steven L. Allen,et al. Multiple Distinct Sets of Stereotyped Antigen Receptors Indicate a Role for Antigen in Promoting Chronic Lymphocytic Leukemia , 2004, The Journal of experimental medicine.
[12] Michael R. Anderberg,et al. Cluster Analysis for Applications , 1973 .
[13] Anna Tramontano,et al. A database of immunoglobulins with integrated tools: DIGIT , 2011, Nucleic Acids Res..
[14] L. Rassenti,et al. Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors. , 1998, The Journal of clinical investigation.
[15] Guillermo Sapiro,et al. Shapes of antibody binding sites: qualitative and quantitative analyses based on a geomorphic classification scheme. , 2006, The Journal of organic chemistry.
[16] T. T. Wu,et al. AN ANALYSIS OF THE SEQUENCES OF THE VARIABLE REGIONS OF BENCE JONES PROTEINS AND MYELOMA LIGHT CHAINS AND THEIR IMPLICATIONS FOR ANTIBODY COMPLEMENTARITY , 1970, The Journal of experimental medicine.
[17] K. Stamatopoulos,et al. Extensive intraclonal diversification in a subgroup of chronic lymphocytic leukemia patients with stereotyped IGHV4-34 receptors: implications for ongoing interactions with antigen. , 2009, Blood.
[18] Yang Zhang,et al. Scoring function for automated assessment of protein structure template quality , 2004, Proteins.
[19] S. Malek,et al. Chronic Lymphocytic Leukemia , 2019, Methods in Molecular Biology.
[20] M. Grever,et al. National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. , 1996, Blood.
[21] Göran Roos,et al. Somatically mutated Ig V(H)3-21 genes characterize a new subset of chronic lymphocytic leukemia. , 2002, Blood.
[22] E. Meffre,et al. Chronic Lymphocytic Leukemia Cells Recognize Conserved Epitopes Associated with Apoptosis and Oxidation , 2008, Molecular medicine.
[23] H. Döhner,et al. Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status. , 2005, Blood.
[24] D. Rossi,et al. Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: results from an Italian multicentre study , 2009, British journal of haematology.
[25] P. Labute,et al. Antibody modeling assessment , 2011, Proteins.
[26] Paolo Marcatili,et al. PIGS: automatic prediction of antibody structures , 2008, Bioinform..
[27] Luca Varani,et al. Computational Docking of Antibody-Antigen Complexes, Opportunities and Pitfalls Illustrated by Influenza Hemagglutinin , 2011, International journal of molecular sciences.
[28] Göran Roos,et al. Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia. , 2004, Blood.
[29] N. Chiorazzi,et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. , 1999, Blood.
[30] Andrew C. R. Martin,et al. Analysis of the antigen combining site: correlations between length and sequence composition of the hypervariable loops and the nature of the antigen. , 2003, Journal of molecular biology.
[31] M. Minden,et al. Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling , 2012, Nature.
[32] A. Lesk,et al. Canonical structures for the hypervariable regions of immunoglobulins. , 1987, Journal of molecular biology.
[33] Andrew J. Martin,et al. Antibody-antigen interactions: contact analysis and binding site topography. , 1996, Journal of molecular biology.
[34] Kostas Stamatopoulos,et al. Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies. , 2012, Blood.
[35] T J Hamblin,et al. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. , 1999, Blood.
[36] G. Juliusson,et al. Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: implicating recognition of a common antigen epitope. , 2003, Blood.
[37] K. Stamatopoulos,et al. Evidence for the significant role of immunoglobulin light chains in antigen recognition and selection in chronic lymphocytic leukemia. , 2008, Blood.
[38] F. Berger,et al. Over 30% of patients with splenic marginal zone lymphoma express the same immunoglobulin heavy variable gene: ontogenetic implications. , 2012, Leukemia.
[39] G. Gaidano,et al. Similarities and Differences Between the Light and Heavy Chain Ig Variable Region Gene Repertoires in Chronic Lymphocytic Leukemia , 2006, Molecular medicine.
[40] E. Ghia,et al. Comprehensive characterization of IGHV3-21-expressing B-cell chronic lymphocytic leukemia: an Italian multicenter study. , 2007, Blood.
[41] Nikolaos Laoutaris,et al. Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis. , 2007, Blood.
[42] Adam Zemla,et al. LGA: a method for finding 3D similarities in protein structures , 2003, Nucleic Acids Res..
[43] Anna Tramontano,et al. Remarkably similar antigen receptors among a subset of patients with chronic lymphocytic leukemia. , 2004, The Journal of clinical investigation.
[44] Sean R. Eddy,et al. Profile hidden Markov models , 1998, Bioinform..
[45] A Tramontano,et al. Conformations of the third hypervariable region in the VH domain of immunoglobulins. , 1998, Journal of molecular biology.
[46] J. Gribben,et al. Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins. , 2004, Blood.
[47] D. Rossi,et al. Biological and clinical significance of stereotyped B-cell receptors in chronic lymphocytic leukemia , 2010, Haematologica.
[48] Nathan A. Baker,et al. Electrostatics of nanosystems: Application to microtubules and the ribosome , 2001, Proceedings of the National Academy of Sciences of the United States of America.