Simple jury predicts protein secondary structure best

. Affiliations 1 CUBIC, Columbia Univ., Dept. of Biochemistry and Molecular Biophysics, 650 West 168th Street, New York, NY 10032, USA 2 Univ. of California, Irvine, Dept. of Information and Computer Science, Institute of Genomics and Bioinformatics, Irvine, CA92697, USA 3 European Bioinformatics Institute, Genome Campus, Hinxton, Cambs CB10 1SD, England 4 The Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambs CB10 1SA, England 5 Columbia Univ., Dept. of Chemistry, 3000 Broadway MC 3167, New York, NY 10027, USA 6 Dept. of Biological Sciences, Brunel Univ., 274348, Uxbridge, Middlesex UB8 3PH, England 7 Computer Engineering, Univ. of California, Santa Cruz, Santa Cruz, CA 95064, USA 8 The Univ. of Wales Aberystwyth, Dept. of Computer Science, Penglais, Ceredigion, SY23 3DB, Wales, UK * Corresponding author: rost@columbia.edu, http://cubic.bioc.columbia.edu/ Abstract

[1]  Thomas L. Madden,et al.  Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. , 1997, Nucleic acids research.

[2]  G J Barton,et al.  Application of multiple sequence alignment profiles to improve protein secondary structure prediction , 2000, Proteins.

[3]  B. Matthews.  Comparison of the predicted and observed secondary structure of T4 phage lysozyme. , 1975, Biochimica et biophysica acta.

[4]  Adel Said Elmaghraby,et al.  Is it better to combine predictions? , 2000, Protein engineering.

[5]  B. Rost,et al.  Combining evolutionary information and neural networks to predict protein secondary structure , 1994, Proteins.

[6]  B. Rost.  PHD: predicting one-dimensional protein structure by profile-based neural networks. , 1996, Methods in enzymology.

[7]  R. King,et al.  Identification and application of the concepts important for accurate and reliable protein secondary structure prediction , 1996, Protein science : a publication of the Protein Society.

[8]  K Karplus,et al.  Predicting protein structure using only sequence information , 1999, Proteins.

[9]  Marc A. Martí-Renom,et al.  EVA: continuous automatic evaluation of protein structure prediction servers , 2001, Bioinform..

[10]  B. Rost,et al.  Alignments grow, secondary structure prediction improves , 2002, Proteins.

[11]  M Ouali,et al.  Cascaded multiple classifiers for secondary structure prediction , 2000, Protein science : a publication of the Protein Society.

[12]  Pierre Baldi,et al.  Bioinformatics - the machine learning approach (2. ed.) , 2000 .

[13]  B. Rost,et al.  Prediction of protein secondary structure at better than 70% accuracy. , 1993, Journal of molecular biology.

[14]  M. Sternberg,et al.  Prediction of protein secondary structure and active sites using the alignment of homologous sequences. , 1987, Journal of molecular biology.

[15]  B. Rost,et al.  A modified definition of Sov, a segment‐based measure for protein secondary structure prediction assessment , 1999, Proteins.

[16]  B. Rost,et al.  Redefining the goals of protein secondary structure prediction. , 1994, Journal of molecular biology.

[17]  Giovanni Soda,et al.  Exploiting the past and the future in protein secondary structure prediction , 1999, Bioinform..

[18]  A A Salamov,et al.  Prediction of protein secondary structure by combining nearest-neighbor algorithms and multiple sequence alignments. , 1995, Journal of molecular biology.

[19]  Liam J. McGuffin,et al.  The PSIPRED protein structure prediction server , 2000, Bioinform..

[20]  D T Jones,et al.  Protein secondary structure prediction based on position-specific scoring matrices. , 1999, Journal of molecular biology.

[21]  P. Argos,et al.  Incorporation of non-local interactions in protein secondary structure prediction from the amino acid sequence. , 1996, Protein engineering.

[22]  J. Garnier,et al.  Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. , 1978, Journal of molecular biology.

[23]  Volker A. Eyrich,et al.  EVA: Large‐scale analysis of secondary structure prediction , 2001, Proteins.

[24]  J. Thompson,et al.  Using CLUSTAL for multiple sequence alignments. , 1996, Methods in enzymology.

[25]  F E Cohen,et al.  Evaluation of current techniques for Ab initio protein structure prediction , 1995, Proteins.