Seizure‐related modulation of systemic arterial blood pressure in focal epilepsy

Cardiorespiratory function alterations are commonly observed with epileptic seizures and may lead to syncope and sudden unexpected death in epilepsy (SUDEP). Although most previous research has focused on controlling heart rate (HR) and respiration, little is known about seizure‐related regulation of systemic blood pressure (BP). Herein, we have investigated whether the periictal modulation of systemic BP and HR depends on seizure characteristics.

[1]  P. Cortelli,et al.  Autonomic and hormonal ictal changes in gelastic seizures from hypothalamic hamartomas. , 1998, Electroencephalography and clinical neurophysiology.

[2]  M. Sperling,et al.  Heart rate and blood pressure in sudden unexpected death in epilepsy (SUDEP) , 2016, Epilepsy Research.

[3]  Chin-Shang Li,et al.  Ictal hypoxemia in localization-related epilepsy: analysis of incidence, severity and risk factors. , 2008, Brain : a journal of neurology.

[4]  Josemir W. Sander,et al.  Sudden unexpected death in epilepsy: risk factors and potential pathomechanisms , 2009, Nature Reviews Neurology.

[5]  J. Britton,et al.  Electrocardiographic and oximetric changes during partial complex and generalized seizures , 2011, Epilepsy Research.

[6]  Philippe Ryvlin,et al.  Sudden unexpected death in epilepsy: current knowledge and future directions , 2008, The Lancet Neurology.

[7]  Masud Seyal,et al.  Respiratory changes with seizures in localization‐related epilepsy: Analysis of periictal hypercapnia and airflow patterns , 2010, Epilepsia.

[8]  J. V. Van Buren,et al.  Some autonomic concomitants of ictal automatism; a study of temporal lobe attacks. , 1958, Brain : a journal of neurology.

[9]  Orrin Devinsky,et al.  Effects of Seizures on Autonomic and Cardiovascular Function , 2004, Epilepsy currents.

[10]  Farhad Kaffashi,et al.  Significant postictal hypotension: Expanding the spectrum of seizure‐induced autonomic dysregulation , 2013, Epilepsia.

[11]  M. Stek,et al.  Beat-to-Beat Hemodynamic Monitoring During Electroconvulsive Therapy , 2011, The journal of ECT.

[12]  P. Guyenet.  The sympathetic control of blood pressure , 2006, Nature Reviews Neuroscience.

[13]  Bas A J M de Mol,et al.  Noninvasive Continuous Arterial Blood Pressure Monitoring with Nexfin® , 2012, Anesthesiology.

[14]  H. Ikram,et al.  Paroxysmal hypertension during a complex partial seizure , 2001, Journal of neurology, neurosurgery, and psychiatry.

[15]  P. Cortelli,et al.  Ictal bradycardia in partial epileptic seizures: Autonomic investigation in three cases and literature review. , 2001, Brain : a journal of neurology.

[16]  O. Devinsky,et al.  Cerebral autoregulation improves in epilepsy patients after temporal lobe surgery , 2004, Journal of Neurology.

[17]  J. H. Cross,et al.  Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005–2009 , 2010, Epilepsia.

[18]  C Baumgartner,et al.  Autonomic symptoms during epileptic seizures. , 2001, Epileptic disorders : international epilepsy journal with videotape.

[19]  J. Britton,et al.  The treatment of ictal asystole with cardiac pacing , 2011, Epilepsia.

[20]  W. Oertel,et al.  NK and CD4+ T cell changes in blood after seizures in temporal lobe epilepsy , 2008, Experimental Neurology.

[21]  Orrin Devinsky,et al.  Sudden, unexpected death in epilepsy. , 2011, The New England journal of medicine.

[22]  Wouter Wieling,et al.  Nexfin noninvasive continuous blood pressure validated against Riva-Rocci/Korotkoff. , 2009, American journal of hypertension.

[23]  A. Schulze-Bonhage,et al.  Incidence and mechanisms of cardiorespiratory arrests in epilepsy monitoring units (MORTEMUS): a retrospective study , 2013, The Lancet Neurology.

[24]  M. Aminoff,et al.  Changes in plasma catecholamines after tonic‐clonic seizures , 1984, Neurology.

[25]  Angela Marchi,et al.  Heart rate variability in untreated newly diagnosed temporal lobe epilepsy: Evidence for ictal sympathetic dysregulation , 2016, Epilepsia.

[26]  Jose-Alberto Palma,et al.  Neural control of the heart , 2014, Neurology.

[27]  J. Girvin,et al.  Cardiovascular effects of human insular cortex stimulation , 1992, Neurology.

[28]  E. R. Locatelli,et al.  Video-electrographic and clinical features in patients with ictal asystole , 2007, Neurology.

[29]  J. G. van Dijk,et al.  The semiology of tilt-induced reflex syncope in relation to electroencephalographic changes. , 2014, Brain : a journal of neurology.

[30]  D. Paterson,et al.  Electrical stimulation of the midbrain increases heart rate and arterial blood pressure in awake humans , 2002, The Journal of physiology.

[31]  J. M. Van Buren,et al.  Some autonomic concomitants of ictal automatism; a study of temporal lobe attacks. , 1958 .

[32]  R R Diehl,et al.  Spontaneous oscillations in cerebral blood flow velocities in middle cerebral arteries in control subjects and patients with epilepsy. , 1997, Stroke.

[33]  R. Kuzniecky,et al.  Cardiovascular and neuroendocrine features of Panayiotopoulos syndrome in three siblings , 2011, Epilepsy & Behavior.

[34]  H. Nornes,et al.  Circulatory and respiratory changes in spontaneous epileptic seizures in man. , 1974, European neurology.

[35]  C. Saper.  The central autonomic nervous system: conscious visceral perception and autonomic pattern generation. , 2002, Annual review of neuroscience.

[36]  H. Blumenfeld,et al.  Consciousness and epilepsy: why are complex-partial seizures complex? , 2009, Progress in brain research.

[37]  Orrin Devinsky,et al.  Impaired baroreflex function in temporal lobe epilepsy , 2006, Journal of Neurology.

[38]  Matthew C. Walker,et al.  Enhanced QT shortening and persistent tachycardia after generalized seizures , 2010, Neurology.

[39]  R Bandler,et al.  Lateralized and widespread brain activation during transient blood pressure elevation revealed by magnetic resonance imaging , 2000, The Journal of comparative neurology.

[40]  Matthew R. Ely,et al.  Blood pressure regulation X: what happens when the muscle pump is lost? Post-exercise hypotension and syncope , 2013, European Journal of Applied Physiology.

[41]  J. Peňáz.  [A portable finger plethysmograph]. , 1954, Scripta medica.