IDH1 mutations in grade II astrocytomas are associated with unfavorable progression‐free survival and prolonged postrecurrence survival
暂无分享,去创建一个
A. Peraud | H. Kretzschmar | S. Kreth | F. Kreth | J. Tonn | N. Thon | S. Eigenbrod | J. Lutz
[1] B. Christensen,et al. DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma. , 2011, Journal of the National Cancer Institute.
[2] Jean-Yves Delattre,et al. Methylation profiling identifies 2 groups of gliomas according to their tumorigenesis. , 2011, Neuro-oncology.
[3] T. Haferlach,et al. IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status. , 2010, Blood.
[4] Karsten Wrede,et al. Molecular classification of low-grade diffuse gliomas. , 2010, The American journal of pathology.
[5] R. Guillevin,et al. IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas , 2010, Neurology.
[6] C. Hoogenraad,et al. Segregation of non‐p.R132H mutations in IDH1 in distinct molecular subtypes of glioma , 2010, Human mutation.
[7] Pieter Wesseling,et al. IDH1 and IDH2 Mutations Are Prognostic but not Predictive for Outcome in Anaplastic Oligodendroglial Tumors: A Report of the European Organization for Research and Treatment of Cancer Brain Tumor Group , 2010, Clinical Cancer Research.
[8] E. Gottlieb,et al. IDH1 mutations in gliomas: when an enzyme loses its grip. , 2010, Cancer cell.
[9] G. Reifenberger,et al. NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[10] L. Liau,et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate , 2009, Nature.
[11] Andrew P. Stubbs,et al. Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology. , 2009, Cancer research.
[12] P. Kleihues,et al. IDH1 Mutations as Molecular Signature and Predictive Factor of Secondary Glioblastomas , 2009, Clinical Cancer Research.
[13] K. Hoang-Xuan,et al. Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[14] David T. W. Jones,et al. IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas. , 2009, Neuro-oncology.
[15] Christian Mawrin,et al. Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas , 2009, Acta Neuropathologica.
[16] Kun-Liang Guan,et al. Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1α , 2009, Science.
[17] P. Kleihues,et al. IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. , 2009, The American journal of pathology.
[18] F. Ducray,et al. IDH1 and IDH2 mutations in gliomas. , 2009, The New England journal of medicine.
[19] D. Busam,et al. An Integrated Genomic Analysis of Human Glioblastoma Multiforme , 2008, Science.
[20] M. Aghili,et al. Hydroxyglutaric aciduria and malignant brain tumor: a case report and literature review , 2008, Journal of Neuro-Oncology.
[21] G. Reifenberger,et al. Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas , 2007, International journal of cancer.
[22] Jeen-Woo Park,et al. Regulation of singlet oxygen-induced apoptosis by cytosolic NADP+-dependent isocitrate dehydrogenase , 2007, Molecular and Cellular Biochemistry.
[23] E. Struys. D-2-Hydroxyglutaric aciduria: Unravelling the biochemical pathway and the genetic defect , 2006, Journal of Inherited Metabolic Disease.
[24] A. Peraud,et al. Prognostic impact of TP53 mutation status for adult patients with supratentorial World Health Organization Grade II astrocytoma or oligoastrocytoma , 2004, Cancer.
[25] Y. Katayama,et al. Promoter Hypermethylation of the DNA Repair Gene O6‐Methylguanine‐DNA Methyltransferase is an Independent Predictor of Shortened Progression Free Survival in Patients with Low‐grade Diffuse Astrocytomas , 2003, Brain pathology.
[26] P. Kleihues,et al. Prognostic impact of TP53 mutations and P53 protein overexpression in supratentorial WHO grade II astrocytomas and oligoastrocytomas. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.
[27] M. Brada. Pathology and Genetics of Tumours of the Nervous System , 2001, British Journal of Cancer.
[28] Scar,et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. , 2000, The New England journal of medicine.
[29] G. Semenza,et al. Expression of hypoxia‐inducible factor 1α in brain tumors , 2000 .
[30] R. Colman,et al. Identification by Mutagenesis of Arginines in the Substrate Binding Site of the Porcine NADP-dependent Isocitrate Dehydrogenase* , 2000, The Journal of Biological Chemistry.
[31] G. Semenza,et al. Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression. , 2000, Cancer.
[32] G. Jennings,et al. Expression and mutagenesis of mammalian cytosolic NADP+-specific isocitrate dehydrogenase. , 1997, Biochemistry.
[33] E. Kaplan,et al. Nonparametric Estimation from Incomplete Observations , 1958 .
[34] D. Karnofsky. The clinical evaluation of chemotherapeutic agents in cancer , 1949 .
[35] D.,et al. Regression Models and Life-Tables , 2022 .