Dynamic focusing in ultrasound hyperthermia treatments using implantable hydrophone arrays

A prototype 16-element needle hydrophone array has been designed, fabricated and characterized. The primary use of this array is to provide acoustic feedback during ultrasound hyperthermia treatments. This feedback can be used to compensate for patient motion and tissue inhomogeneities by controlling the phased array driving patterns. It can also be used in adaptive dynamic focusing, a procedure which enables the phased array to focus at points away from specified control points. The hydrophone array consists of a PVDF sheet, which covers a silicon substrate carrier that contains the signal electrodes of the individual acoustic sensors. A complete description of the hydrophone array and its characteristics is given in this paper. The aberration correction and motion compensation algorithms are also described, and some experimental results are shown. Finally, a Taylor series based adaptive dynamic focusing method for phased arrays based on a set of discrete hydrophone array measurements is described. This algorithm does not require any prior knowledge of the applicator geometry and all the parameters needed for correction can be measured directly at the hydrophone array sensor locations.<<ETX>>

[1]  Paul L. Carson,et al.  Micromachining for improvement of integrated ultrasonic transducer sensitivity , 1990 .

[2]  M. O’Donnell,et al.  Acoustic feedback for hyperthermia phased-array applicators: aberration correction, motion compensation and multiple focusing in the presence of tissue inhomogeneities , 1991, IEEE 1991 Ultrasonics Symposium,.

[3]  P. VanBaren,et al.  A new algorithm for dynamic focusing of phased-array hyperthermia applicators through tissue inhomogeneities , 1993 .

[4]  Gerhard M. Sessler,et al.  Piezoelectricity in polyvinylidenefluoride , 1981 .

[5]  Hong Wang,et al.  Phase aberration correction and motion compensation for ultrasonic hyperthermia phased arrays: experimental results , 1994, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[6]  Emad S. Ebbini,et al.  Characterization of a needle hydrophone array for acoustic feedback during ultrasound hyperthermia treatments , 1992, IEEE 1992 Ultrasonics Symposium Proceedings.

[7]  M. O’Donnell,et al.  Phase-aberration correction using signals from point reflectors and diffuse scatterers: basic principles , 1988, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[8]  C.A. Cain,et al.  Multiple-focus ultrasound phased-array pattern synthesis: optimal driving-signal distributions for hyperthermia , 1989, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[9]  M. O'Donnell,et al.  Adaptive 2D cylindrical section phased array system for ultrasonic hyperthermia , 1992, IEEE 1992 Ultrasonics Symposium Proceedings.

[10]  A. L. Robinson,et al.  Crosstalk reduction with a micromachined diaphragm structure for integrated ultrasound transducer arrays , 1992, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[11]  M. O'Donnell,et al.  Phase-aberration correction using signals from point reflectors and diffuse scatterers: measurements , 1988, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.