Prevalence of renal disease in asymptomatic heroin addicts.

Renal function was studied in 145 asymptomatic male heroin addicts admitted to a methadone detoxification program. The mean duration of addiction was ten years. Three patients had protein excretion greater than 150 mg/24 hr; in one of these, membranous glomerulonephritis was found. All except one had normal creatinine clearance. Hypertension was present in 2.7%. This study does not support the concept that heroin addiction is associated with a high prevalence of renal disease.

[1]  G. Eknoyan,et al.  Renal involvement in drug abuse. , 1973, Archives of internal medicine.

[2]  P. Kohler Clinical immune complex disease. Manifestations in systemic lupus erythematosus and hepatitis B virus infection. , 1973, Medicine.

[3]  R. Rieselbach,et al.  Factors influencing the increase in glomerular filtration rate in the remaining kidney of transplant donors. , 1973, The American journal of medicine.

[4]  P. Cushman,et al.  Hyperimmunoglobulinemia associated with narcotic addiction. Effects of methadone maintenance treatment. , 1973, The American journal of medicine.

[5]  S. Gorbach,et al.  Favorable experience with bacterial endocarditis in heroin addicts. , 1973, Annals of internal medicine.

[6]  G. Eknoyan,et al.  Renal morphological and immunological changes associated with acute viral hepatitis. , 1972, Kidney international.

[7]  G. Striker,et al.  THE IMMUNE COMPLEX GLOMERULONEPHRITIS OF BACTERIAL ENDOCARDITIS , 1972, Medicine.

[8]  M. Goldblatt,et al.  Renal Lesions in Heroin Addicts , 1972 .

[9]  M. Tannenbaum,et al.  Nephrotic syndrome in heroin addicts. , 1972, Lancet.

[10]  P. Stastny,et al.  Glomerulonephritis with deposition of Australia antigen-antibody complexes in glomerular basement membrane. , 1971, Lancet.

[11]  Y. Challenor,et al.  Acute myoglobinuria associated with heroin addiction. , 1971, JAMA.

[12]  D. Tatter,et al.  Necrotizing angiitis associated with drug abuse. , 1970, The New England journal of medicine.

[13]  R. Williams,et al.  Increased opsonic capacity of serum in chronic heroin addiction. , 1970, Annals of internal medicine.

[14]  J. Ball,et al.  Causes of death among institutionalized narcotic addicts. , 1970, Journal of chronic diseases.

[15]  M. Shearn,et al.  Acute diffuse glomerulonephritis in acute staphylococcal endocarditis. , 1969, Annals of internal medicine.

[16]  M. Cantin,et al.  Evidence for the nephrotoxicity of morphine sulfate in rats. , 1969, Canadian journal of physiology and pharmacology.

[17]  J. Sapira The narcotic addict as a medical patient. , 1968, The American journal of medicine.

[18]  S. Millian,et al.  Serologic investigations in narcotic addicts. I. Syphilis, lymphogranuloma venereum, herpes simplex, and Q fever. , 1968, Annals of internal medicine.

[19]  D. Louria,et al.  The major medical complications of heroin addiction. , 1967, Annals of internal medicine.

[20]  C E Cherubin,et al.  The medical sequelae of narcotic addiction. , 1967, Annals of internal medicine.

[21]  E. Alpen,et al.  A clinical appraisal of the plasma concentration and endogenous clearance of creatinine. , 1962, The American journal of medicine.

[22]  P. Vestergaard,et al.  Constancy of urinary creatinine excretion. , 1958, The Journal of laboratory and clinical medicine.