AChE and RACK1 Promote the Anti-Inflammatory Properties of Fluoxetine

[1]  B. Kolisnyk,et al.  Regulation of cholinergic activity by the vesicular acetylcholine transporter. , 2013, The Biochemical journal.

[2]  Y. Mineur,et al.  Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety- and depression-like behavior , 2013, Proceedings of the National Academy of Sciences.

[3]  U. Heinemann,et al.  Fluoxetine induces vasodilatation of cerebral arterioles by co-modulating NO/muscarinic signalling , 2012, Journal of cellular and molecular medicine.

[4]  Ramyavardhanee Chandrasekaran,et al.  Structure of human Rack1 protein at a resolution of 2.45 Å. , 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

[5]  Ryan G. Coleman,et al.  ZINC: A Free Tool to Discover Chemistry for Biology , 2012, J. Chem. Inf. Model..

[6]  A. Taly,et al.  α7-Nicotinic acetylcholine receptors: an old actor for new different roles. , 2012, Current drug targets.

[7]  B. Hoebel,et al.  Corticotropin-releasing factor in the nucleus accumbens shell induces swim depression, anxiety, and anhedonia along with changes in local dopamine/acetylcholine balance , 2012, Neuroscience.

[8]  H. Soreq,et al.  Post-traumatic anxiety associates with failure of the innate immune receptor TLR9 to evade the pro-inflammatory NFκB pathway , 2012, Translational Psychiatry.

[9]  G. Hartmann,et al.  Stressing hematopoiesis and immunity: an acetylcholinesterase window into nervous and immune system interactions , 2012, Front. Mol. Neurosci..

[10]  J. Leza,et al.  Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression , 2011, Journal of Neuroinflammation.

[11]  Zhiping Weng,et al.  Accelerating Protein Docking in ZDOCK Using an Advanced 3D Convolution Library , 2011, PloS one.

[12]  De-xiang Liu,et al.  Anti-inflammatory effects of fluoxetine in lipopolysaccharide(LPS)-stimulated microglial cells , 2011, Neuropharmacology.

[13]  Michelle R. Lennartz,et al.  Protein Kinase C and Toll-Like Receptor Signaling , 2011, Enzyme research.

[14]  G. Baillie,et al.  Interaction with receptor for activated C-kinase 1 (RACK1) sensitizes the phosphodiesterase PDE4D5 towards hydrolysis of cAMP and activation by protein kinase C , 2010, The Biochemical journal.

[15]  J. Sussman,et al.  Acetylcholinesterase: from 3D structure to function. , 2010, Chemico-biological interactions.

[16]  B. Leonard.  The concept of depression as a dysfunction of the immune system. , 2010, Current immunology reviews.

[17]  S. Maier,et al.  Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity , 2010, Neuroscience.

[18]  S. Akira,et al.  The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors , 2010, Nature Immunology.

[19]  D. Ron,et al.  Epigenetic Regulation of BDNF Expression via the Scaffolding Protein RACK1* , 2010, The Journal of Biological Chemistry.

[20]  F. Brennan,et al.  Fluoxetine and citalopram exhibit potent antiinflammatory activity in human and murine models of rheumatoid arthritis and inhibit toll-like receptors. , 2010, Arthritis and rheumatism.

[21]  H. Soreq,et al.  MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. , 2009, Immunity.

[22]  Kevin J. Tracey,et al.  The Neurology of the Immune System: Neural Reflexes Regulate Immunity , 2009, Neuron.

[23]  A. Olson,et al.  AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading , 2009, J. Comput. Chem..

[24]  Hayyoung Lee,et al.  The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex , 2009, Nature.

[25]  A. Ferry,et al.  Effect of fluoxetine on neuromuscular function in acetylcholinesterase (AChE) knockout mice. , 2008, Chemico-biological interactions.

[26]  K. Miyake,et al.  TLR accessory molecules. , 2008, Current opinion in immunology.

[27]  E. Moilanen,et al.  Inhibition of protein kinase C βII downregulates tristetraprolin expression in activated macrophages , 2008, Inflammation Research.

[28]  Y. Ben-Shaul,et al.  Acetylcholinesterase/C terminal binding protein interactions modify Ikaros functions, causing T lymphopenia , 2007, Leukemia.

[29]  P. Scully,et al.  Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy. , 2007, Journal of psychiatric research.

[30]  F. Mora,et al.  Stress, prefrontal cortex and environmental enrichment: Studies on dopamine and acetylcholine release and working memory performance in rats , 2007, Behavioural Brain Research.

[31]  R. Medzhitov,et al.  Phosphoinositide-Mediated Adaptor Recruitment Controls Toll-like Receptor Signaling , 2006, Cell.

[32]  H. Soreq,et al.  Stress-induced cholinergic signaling promotes inflammation-associated thrombopoiesis. , 2006, Blood.

[33]  H. Soreq,et al.  RACK1 has the nerve to act: Structure meets function in the nervous system , 2006, Progress in Neurobiology.

[34]  H. Soreq,et al.  Hydrolytic and Nonenzymatic Functions of Acetylcholinesterase Comodulate Hemopoietic Stress Responses1 , 2006, The Journal of Immunology.

[35]  J. Frank,et al.  Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome , 2004, EMBO reports.

[36]  J. Sussman,et al.  The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix , 2004, The EMBO journal.

[37]  K. Tang,et al.  Spatial and Temporal Regulation of RACK1 Function and N-methyl-D-aspartate Receptor Activity through WD40 Motif-mediated Dimerization* , 2004, Journal of Biological Chemistry.

[38]  A. Tarakhovsky,et al.  Essential role of Src-family protein tyrosine kinases in NF-κB activation during B cell development , 2003, Nature Immunology.

[39]  H. Soreq,et al.  Interaction of “readthrough” acetylcholinesterase with RACK1 and PKCβII correlates with intensified fear-induced conflict behavior , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[40]  Kevin J. Tracey,et al.  The inflammatory reflex , 2002, Nature.

[41]  M. Goldman,et al.  Critical role of protein kinase C ϵ for lipopolysaccharide‐induced IL‐12 synthesis in monocyte‐derived dendritic cells , 2002, European journal of immunology.

[42]  N. Brandon,et al.  Receptor for Activated C Kinase-1 Facilitates Protein Kinase C-Dependent Phosphorylation and Functional Modulation of GABAA Receptors with the Activation of G-Protein-Coupled Receptors , 2002, The Journal of Neuroscience.

[43]  F. Golley,et al.  Structure and Function , 2002, Science's STKE.

[44]  D. Mochly‐Rosen,et al.  Binding Specificity for RACK1 Resides in the V5 Region of βII Protein Kinase C* , 2001, The Journal of Biological Chemistry.

[45]  H. Soreq,et al.  Acetylcholinesterase — new roles for an old actor , 2001, Nature Reviews Neuroscience.

[46]  P. Renshaw,et al.  Increased orbitofrontal cortex levels of choline in depressed adolescents as detected by in vivo proton magnetic resonance spectroscopy , 2000, Biological Psychiatry.

[47]  Edwin J. Weeber,et al.  A Role for the β Isoform of Protein Kinase C in Fear Conditioning , 2000, The Journal of Neuroscience.

[48]  K. Tracey,et al.  Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin , 2000, Nature.

[49]  A. Altman,et al.  NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[50]  N. Brandon,et al.  Subunit-Specific Association of Protein Kinase C and the Receptor for Activated C Kinase with GABA Type A Receptors , 1999, The Journal of Neuroscience.

[51]  I. Diamond,et al.  Coordinated Movement of RACK1 with Activated βIIPKC* , 1999, The Journal of Biological Chemistry.

[52]  Yoshinori Nagai,et al.  MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4 , 1999, The Journal of experimental medicine.

[53]  T. Kodadek,et al.  Chemistry for the analysis of protein-protein interactions: rapid and efficient cross-linking triggered by long wavelength light. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[54]  M F Sanner,et al.  Python: a programming language for software integration and development. , 1999, Journal of molecular graphics & modelling.

[55]  C. Chen,et al.  Antisense oligonucleotides targeting protein kinase C-alpha, -beta I, or -delta but not -eta inhibit lipopolysaccharide-induced nitric oxide synthase expression in RAW 264.7 macrophages: involvement of a nuclear factor kappa B-dependent mechanism. , 1998, Journal of immunology.

[56]  R. Miledi,et al.  Effects of fluoxetine on wild and mutant neuronal α7 nicotinic receptors , 1998, Molecular Psychiatry.

[57]  A. Rush,et al.  Are fluoxetine plasma levels related to outcome in obsessive-compulsive disorder? , 1996, The American journal of psychiatry.

[58]  A. Tarakhovsky,et al.  Immunodeficiency in Protein Kinase Cβ-Deficient Mice , 1996, Science.

[59]  J. Rybakowski,et al.  Interleukin‐6 Serum Levels in Depressed Patients before and after Treatment with Fluoxetine , 1995, Annals of the New York Academy of Sciences.

[60]  K. Krishnan,et al.  Brain choline in depression: In vivo detection of potential pharmacodynamic effects of antidepressant therapy using hydrogen localized spectroscopy , 1994, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[61]  F. Liew,et al.  Inhibition of nitric oxide synthesis by interleukin‐4 may involve inhibiting the activation of protein kinase C epsilon , 1994, European journal of immunology.

[62]  J. Caldwell,et al.  Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[63]  D. Kioussis,et al.  Accelerated proliferation and interleukin-2 production of thymocytes by stimulation of soluble anti-CD3 monoclonal antibody in transgenic mice carrying a rabbit protein kinase C alpha. , 1992, The Journal of biological chemistry.

[64]  D. Mochly‐Rosen,et al.  Intracellular receptors for activated protein kinase C. Identification of a binding site for the enzyme. , 1991, The Journal of biological chemistry.

[65]  D. Sax,et al.  Cholinergic-adrenergic hypothesis of mania and depression. , 1972, Lancet.

[66]  Comparative Effectiveness Review Number 62 Treatment for Depression After Unsatisfactory Response to SSRIs Executive Summary , 2012 .

[67]  R. Dantzer,et al.  From inflammation to sickness and depression: when the immune system subjugates the brain , 2008, Nature Reviews Neuroscience.

[68]  Y. Nishizuka,et al.  The family of protein kinase C and membrane lipid mediators. , 2002, Journal of diabetes and its complications.

[69]  D. Mochly‐Rosen,et al.  Binding specificity for RACK1 resides in the V5 region of beta II protein kinase C. , 2001, The Journal of biological chemistry.

[70]  J. Sweatt,et al.  A role for the beta isoform of protein kinase C in fear conditioning. , 2000, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[71]  I. Diamond,et al.  Coordinated movement of RACK1 with activated betaIIPKC. , 1999, The Journal of biological chemistry.

[72]  R. Miledi,et al.  Effects of fluoxetine on wild and mutant neuronal alpha 7 nicotinic receptors. , 1998, Molecular psychiatry.

[73]  N. Guex,et al.  SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling , 1997, Electrophoresis.

[74]  A. Tarakhovsky,et al.  Immunodeficiency in protein kinase cbeta-deficient mice. , 1996, Science.

[75]  T. Hennigan,et al.  Erythropoietin and autologous blood donation. Reply , 1989 .