Breast cancer precursors revisited: molecular features and progression pathways

Lopez‐Garcia M A, Geyer F C, Lacroix‐Triki M, Marchió C & Reis‐Filho J S
(2010) Histopathology 57, 171–192
Breast cancer precursors revisited: molecular features and progression pathways

[1]  Jorge S Reis-Filho,et al.  The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade , 2010, The Journal of pathology.

[2]  C. Lawton,et al.  Local Excision Alone Without Irradiation for Ductal Carcinoma In Situ of the Breast: A Trial of the Eastern Cooperative Oncology Group , 2010 .

[3]  A. Ashworth,et al.  An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers , 2010, Breast Cancer Research and Treatment.

[4]  J. Reis-Filho,et al.  Histological and molecular types of breast cancer: is there a unifying taxonomy? , 2009, Nature Reviews Clinical Oncology.

[5]  Alan Mackay,et al.  Microglandular adenosis or microglandular adenoma? A molecular genetic analysis of a case associated with atypia and invasive carcinoma , 2009, Histopathology.

[6]  S. Devries,et al.  Genetic and Phenotypic Characteristics of Pleomorphic Lobular Carcinoma In Situ of the Breast , 2009, The American journal of surgical pathology.

[7]  C. Shriver,et al.  Genomic instability in the breast microenvironment? A critical evaluation of the evidence , 2009, Expert review of molecular diagnostics.

[8]  K. Siziopikou,et al.  Rosen's Breast Pathology , 2009 .

[9]  J. Reis-Filho,et al.  Genetic characterization of breast cancer and implications for clinical management , 2009, Journal of cellular and molecular medicine.

[10]  I. Haviv,et al.  Clonal mutations in the cancer-associated fibroblasts: the case against genetic coevolution. , 2009, Cancer research.

[11]  A. Ashworth,et al.  Tiling Path Genomic Profiling of Grade 3 Invasive Ductal Breast Cancers , 2009, Clinical Cancer Research.

[12]  A. Ashworth,et al.  Loss of 16q in high grade breast cancer is associated with estrogen receptor status: Evidence for progression in tumors with a luminal phenotype? , 2009, Genes, chromosomes & cancer.

[13]  S. Lakhani,et al.  Molecular Evidence for Progression of Microglandular Adenosis (MGA) to Invasive Carcinoma , 2009, The American journal of surgical pathology.

[14]  Sunil R Lakhani,et al.  Pleomorphic lobular carcinoma of the breast: molecular pathology and clinical impact. , 2009, Future oncology.

[15]  S. Schnitt,et al.  Phenotypic Alterations in Ductal Carcinoma In Situ-associated Myoepithelial Cells: Biologic and Diagnostic Implications , 2009, The American journal of surgical pathology.

[16]  Philippe Dessen,et al.  Molecular Characterization of Breast Cancer with High-Resolution Oligonucleotide Comparative Genomic Hybridization Array , 2009, Clinical Cancer Research.

[17]  L. Middleton Histologic Associations and Long-term Cancer Risk in Columnar Cell Lesions of the Breast: A Retrospective Cohort and a Nested Case-Control Study , 2009 .

[18]  Y. Niu,et al.  Genetic changes at specific stages of breast cancer progression detected by comparative genomic hybridization , 2009, Journal of Molecular Medicine.

[19]  A. Ashworth,et al.  A high-resolution integrated analysis of genetic and expression profiles of breast cancer cell lines , 2009, Breast Cancer Research and Treatment.

[20]  Sean Davis,et al.  Molecular Grading of Ductal Carcinoma In situ of the Breast , 2008, Clinical Cancer Research.

[21]  Zoltan Dezso,et al.  Genome-wide functional synergy between amplified and mutated genes in human breast cancer. , 2008, Cancer research.

[22]  D. Dabbs,et al.  Pleomorphic Lobular Carcinoma In Situ (PLCIS) on Breast Core Needle Biopsies: Clinical Significance and Immunoprofile , 2008, The American journal of surgical pathology.

[23]  Gianluca Bontempi,et al.  Biological Processes Associated with Breast Cancer Clinical Outcome Depend on the Molecular Subtypes , 2008, Clinical Cancer Research.

[24]  D. Dabbs,et al.  Frequency and clinical significance of simultaneous association of lobular neoplasia and columnar cell alterations in breast tissue specimens. , 2008, American journal of clinical pathology.

[25]  A. Ashworth,et al.  Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas , 2008, The Journal of pathology.

[26]  J. Benítez,et al.  Distinct genomic aberration patterns are found in familial breast cancer associated with different immunohistochemical subtypes , 2008, Oncogene.

[27]  Jun Yao,et al.  Regulation of in situ to invasive breast carcinoma transition. , 2008, Cancer cell.

[28]  Suzanne M. Brandt,et al.  The "Rosen Triad": tubular carcinoma, lobular carcinoma in situ, and columnar cell lesions. , 2008, Advances in anatomic pathology.

[29]  I. Ellis,et al.  Morphologic and Molecular Evolutionary Pathways of Low Nuclear Grade Invasive Breast Cancers and Their Putative Precursor Lesions: Further Evidence to Support the Concept of Low Nuclear Grade Breast Neoplasia Family , 2008, The American journal of surgical pathology.

[30]  N. Sneige,et al.  Clinical, Histopathologic, and Immunohistochemical Features of Microglandular Adenosis and Transition Into In Situ and Invasive Carcinoma , 2008, The American journal of surgical pathology.

[31]  J. Thiery,et al.  Integrated Genomic and Transcriptomic Analysis of Ductal Carcinoma In situ of the Breast , 2008, Clinical Cancer Research.

[32]  Charles M. Perou,et al.  Ductal Carcinoma In situ and the Emergence of Diversity during Breast Cancer Evolution , 2008, Clinical Cancer Research.

[33]  A. Hanby,et al.  In situ and invasive lobular neoplasia of the breast , 2007, Histopathology.

[34]  F. O'Malley,et al.  An update on apocrine lesions of the breast , 2007, Histopathology.

[35]  C. Quinn,et al.  Columnar cell lesions of the breast , 2007, Histopathology.

[36]  C. Sotiriou,et al.  Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures , 2007, Breast Cancer Research.

[37]  F. Bonetti,et al.  Risk of neoplastic transformation in asymptomatic radial scar. Analysis of 117 cases , 2008, Breast Cancer Research and Treatment.

[38]  Tara L. Naylor,et al.  Estrogen Receptor Status Could Modulate the Genomic Pattern in Familial and Sporadic Breast Cancer , 2007, Clinical Cancer Research.

[39]  Daniel Birnbaum,et al.  Integrated profiling of basal and luminal breast cancers. , 2007, Cancer research.

[40]  S. Ringquist,et al.  Quantification of CpG island methylation in progressive breast lesions from normal to invasive carcinoma. , 2007, Cancer letters.

[41]  S. Tavaré,et al.  High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer , 2007, Genome Biology.

[42]  M. Martel,et al.  Flat DIN 1 (flat epithelial atypia) on core needle biopsy: 63 cases identified retrospectively among 1,751 core biopsies performed over an 8-year period (1992–1999) , 2007, Virchows Archiv.

[43]  J. Rosen,et al.  Modelling breast cancer: one size does not fit all , 2007, Nature Reviews Cancer.

[44]  Rachael Natrajan,et al.  Chromogenic and fluorescent in situ hybridization in breast cancer. , 2007, Human pathology.

[45]  I. Gromova,et al.  Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia , 2007, Molecular oncology.

[46]  I. Ellis,et al.  High Frequency of Coexistence of Columnar Cell Lesions, Lobular Neoplasia, and Low Grade Ductal Carcinoma In Situ With Invasive Tubular Carcinoma and Invasive Lobular Carcinoma , 2007, The American journal of surgical pathology.

[47]  Alan Mackay,et al.  Evaluation of Phi29-based whole-genome amplification for microarray-based comparative genomic hybridisation , 2007, Laboratory Investigation.

[48]  J. Reis-Filho,et al.  Non-operative breast pathology: lobular neoplasia , 2006, Journal of Clinical Pathology.

[49]  J. Reis-Filho,et al.  Non-operative breast pathology: columnar cell lesions , 2006, Journal of Clinical Pathology.

[50]  Kenny Q. Ye,et al.  Novel patterns of genome rearrangement and their association with survival in breast cancer. , 2006, Genome research.

[51]  Ajay N. Jain,et al.  Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. , 2006, Cancer cell.

[52]  Wen-Lin Kuo,et al.  A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. , 2006, Cancer cell.

[53]  Teresa L. Mastracci,et al.  Genomic alterations in lobular neoplasia: A microarray comparative genomic hybridization signature for early neoplastic proliferationin the breast , 2006, Genes, chromosomes & cancer.

[54]  Robert Tibshirani,et al.  Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene‐expression subtypes of breast cancer , 2006, Genes, chromosomes & cancer.

[55]  Jos Jonkers,et al.  Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis. , 2006, Cancer cell.

[56]  M. J. van de Vijver,et al.  Classification of ductal carcinoma in situ by gene expression profiling , 2006, Breast Cancer Research.

[57]  N. Carter,et al.  A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGH , 2006, Oncogene.

[58]  W. Dupont,et al.  Excellent survival, cancer type, and Nottingham grade after atypical lobular hyperplasia on initial breast biopsy , 2006, Cancer.

[59]  I. Ellis,et al.  The management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)? , 2006, European journal of cancer.

[60]  Tae-You Kim,et al.  Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression. , 2006, Cancer research.

[61]  L. Cupples,et al.  Quantitative analysis of allele imbalance supports atypical ductal hyperplasia lesions as direct breast cancer precursors , 2006, The Journal of pathology.

[62]  A. Nobel,et al.  The molecular portraits of breast tumors are conserved across microarray platforms , 2006, BMC Genomics.

[63]  V. Eusebi,et al.  Genetic similarities and differences between lobular in situ neoplasia (LN) and invasive lobular carcinoma of the breast , 2006, Virchows Archiv.

[64]  W. Dupont,et al.  Interdependence of radial scar and proliferative disease with respect to invasive breast carcinoma risk in patients with benign breast biopsies , 2006, Cancer.

[65]  Carissa A. Sanchez,et al.  Genetic clonal diversity predicts progression to esophageal adenocarcinoma , 2006, Nature Genetics.

[66]  Yan Peng,et al.  Molecular alterations in columnar cell lesions of the breast , 2006, Modern Pathology.

[67]  M. J. van de Vijver,et al.  Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis. , 2006, Journal of the National Cancer Institute.

[68]  R. Millis,et al.  Problems in Breast Pathology , 2006, Virchows Archiv.

[69]  Sunil R Lakhani,et al.  The molecular genetics of breast cancer: the contribution of comparative genomic hybridization. , 2005, Pathology, research and practice.

[70]  C. Perou,et al.  Molecular portraits and 70-gene prognosis signature are preserved throughout the metastatic process of breast cancer. , 2005, Cancer research.

[71]  R. Elledge,et al.  Premalignant and In Situ Breast Disease: Biology and Clinical Implications , 2005, Annals of Internal Medicine.

[72]  A. Ashworth,et al.  Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity , 2005, The Journal of pathology.

[73]  Jun Yao,et al.  Distinct epigenetic changes in the stromal cells of breast cancers , 2005, Nature Genetics.

[74]  J. Peterse,et al.  Breast cancer metastasis: markers and models , 2005, Nature Reviews Cancer.

[75]  David Cameron,et al.  Identification of molecular apocrine breast tumours by microarray analysis , 2005, Oncogene.

[76]  W. Dupont,et al.  The natural history of low‐grade ductal carcinoma in situ of the breast in women treated by biopsy only revealed over 30 years of long‐term follow‐up , 2005, Cancer.

[77]  I. Ellis,et al.  Columnar Cell Lesions of the Breast: The Missing Link in Breast Cancer Progression?: A Morphological and Molecular Analysis , 2005, The American journal of surgical pathology.

[78]  F. Tavassoli Breast pathology: rationale for adopting the ductal intraepithelial neoplasia (DIN) classification , 2005, Nature Clinical Practice Oncology.

[79]  S. Lakhani,et al.  Molecular evolution of breast cancer , 2005, The Journal of pathology.

[80]  W. Dupont,et al.  Immunohistochemical Expression of Estrogen Receptor in Enlarged Lobular Units With Columnar Alteration in Benign Breast Biopsies: A Nested Case-Control Study , 2005, The American journal of surgical pathology.

[81]  M. Skolnick Proliferative Breast Disease: Diagnosis and Implications , 2005 .

[82]  Q. Sang,et al.  The significance of focal myoepithelial cell layer disruptions in human breast tumor invasion: a paradigm shift from the "protease-centered" hypothesis. , 2004, Experimental cell research.

[83]  Barbara J. Trask,et al.  Array Comparative Genomic Hybridization Analysis of Genomic Alterations in Breast Cancer Subtypes , 2004, Cancer Research.

[84]  M. J. van de Vijver,et al.  Different mechanisms of chromosome 16 loss of heterozygosity in well‐ versus poorly differentiated ductal breast cancer , 2004, Genes, chromosomes & cancer.

[85]  G Leclercq,et al.  Stable 'portrait' of breast tumors during progression: data from biology, pathology and genetics. , 2004, Endocrine-related cancer.

[86]  Rameen Beroukhim,et al.  Molecular characterization of the tumor microenvironment in breast cancer. , 2004, Cancer cell.

[87]  S. Devries,et al.  Clonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma , 2004, Cancer.

[88]  S. Devries,et al.  Array-based comparative genomic hybridization of ductal carcinoma in situ and synchronous invasive lobular cancer. , 2004, Human pathology.

[89]  John M. Greally,et al.  Epigenomics: beyond CpG islands , 2004, Nature Reviews Genetics.

[90]  Jorma Isola,et al.  Patterns of chromosomal imbalances defines subgroups of breast cancer with distinct clinical features and prognosis. A study of 305 tumors by comparative genomic hybridization. , 2003, Cancer research.

[91]  Annuska M Glas,et al.  Gene expression profiles of primary breast tumors maintained in distant metastases , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[92]  A. Vincent-Salomon [Columnar lesions: a frequent diagnosis in breast pathology!]. , 2003, Annales de pathologie.

[93]  S. Lakhani,et al.  The diagnosis and management of pre-invasive breast disease: Genetic alterations in pre-invasive lesions , 2003, Breast Cancer Research.

[94]  M. J. van de Vijver,et al.  Association of C‐MYC amplification with progression from the in situ to the invasive stage in C‐MYC‐amplified breast carcinomas , 2003, The Journal of pathology.

[95]  J. Herman,et al.  Epigenetic and genetic alterations of APC and CDH1 genes in lobular breast cancer: Relationships with abnormal E‐cadherin and catenin expression and microsatellite instability , 2003, International journal of cancer.

[96]  C. Reynolds,et al.  Microglandular Adenosis With Transition Into Adenoid Cystic Carcinoma of the Breast , 2003, The American journal of surgical pathology.

[97]  S. Schnitt The diagnosis and management of pre-invasive breast disease: Flat epithelial atypia – classification, pathologic features and clinical significance , 2003, Breast Cancer Research.

[98]  S. Lakhani,et al.  The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ , 2003, Breast Cancer Research.

[99]  G. Bratthauer,et al.  A subset of morphologically distinct mammary myoepithelial cells lacks corresponding immunophenotypic markers , 2003, Breast Cancer Research.

[100]  A. Vincent-Salomon,et al.  Columnar Cell Lesions of the Breast , 2003, Advances in anatomic pathology.

[101]  R. Salunga,et al.  Gene expression profiles of human breast cancer progression , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[102]  Kornelia Polyak,et al.  Molecular markers in ductal carcinoma in situ of the breast. , 2003, Molecular cancer research : MCR.

[103]  S. Lakhani,et al.  X-inactivation patch size in human female tissue confounds the assessment of tumor clonality , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[104]  S. Lakhani,et al.  Comparative genomic hybridization analysis of bilateral hyperplasia of usual type of the breast , 2003, The Journal of pathology.

[105]  W. Dupont,et al.  Atypical lobular hyperplasia as a unilateral predictor of breast cancer risk: a retrospective cohort study , 2003, The Lancet.

[106]  J. Haerting,et al.  Gene-expression signatures in breast cancer. , 2003, The New England journal of medicine.

[107]  Horst Buerger,et al.  Usual ductal hyperplasia of the breast is a committed stem (progenitor) cell lesion distinct from atypical ductal hyperplasia and ductal carcinoma in situ , 2002, The Journal of pathology.

[108]  N. Sneige,et al.  Clinical, Histopathologic, and Biologic Features of Pleomorphic Lobular (Ductal-Lobular) Carcinoma In Situ of the Breast: A Report of 24 Cases , 2002, Modern Pathology.

[109]  Martin Widschwendter,et al.  DNA methylation and breast carcinogenesis , 2002, Oncogene.

[110]  B. Delahunt,et al.  Loss of heterozygosity studies revisited: prior quantification of the amplifiable DNA content of archival samples improves efficiency and reliability. , 2002, The Journal of molecular diagnostics : JMD.

[111]  D. Carter,et al.  Rosen's Breast Pathology, 2nd ed. , 2002 .

[112]  C. Foster,et al.  Molecular and genetic abnormalities in radial scar. , 2002, Human pathology.

[113]  L. Cupples,et al.  Loss of heterozygosity or allele imbalance in histologically normal breast epithelium is distinct from loss of heterozygosity or allele imbalance in co-existing carcinomas. , 2002, The American journal of pathology.

[114]  A. Ryan,et al.  Loss of heterozygosity and allelic imbalance in apocrine metaplasia of the breast: microdissection microsatellite analysis , 2002, The Journal of pathology.

[115]  U. Lehmann,et al.  Quantitative assessment of promoter hypermethylation during breast cancer development. , 2002, The American journal of pathology.

[116]  P. V. van Diest,et al.  Ductal epithelial proliferations of the breast: a biological continuum? Comparative genomic hybridization and high‐molecular‐weight cytokeratin expression patterns , 2001, The Journal of pathology.

[117]  B. Brandt,et al.  Genetic characterisation of invasive breast cancer: a comparison of CGH and PCR based multiplex microsatellite analysis. , 2001, Journal of clinical pathology.

[118]  R. Tibshirani,et al.  Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[119]  S. Devries,et al.  Genetic changes in paired atypical and usual ductal hyperplasia of the breast by comparative genomic hybridization. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[120]  S. Sukumar,et al.  Hypermethylation of 14-3-3 σ (stratifin) is an early event in breast cancer , 2001, Oncogene.

[121]  P. V. van Diest,et al.  Ductal invasive G2 and G3 carcinomas of the breast are the end stages of at least two different lines of genetic evolution , 2001, The Journal of pathology.

[122]  R. Roylance,et al.  Multiple ways of silencing E‐cadherin gene expression in lobular carcinoma of the breast , 2001, International journal of cancer.

[123]  V. Eusebi,et al.  Molecular cytogenetic comparison of apocrine hyperplasia and apocrine carcinoma of the breast. , 2001, The American journal of pathology.

[124]  S. Sukumar,et al.  Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer. , 2001, Oncogene.

[125]  M. Merino,et al.  Pleomorphic Lobular Carcinoma: Morphology, Immunohistochemistry, and Molecular Analysis , 2000, The American journal of surgical pathology.

[126]  G. Bratthauer,et al.  Carcinoma Arising in Microglandular Adenosis: An Immunohistochemical Analysis of 20 Intraepithelial and Invasive Neoplasms , 2000, International journal of surgical pathology.

[127]  J. Sloane,et al.  Abnormal regulation of the oestrogen receptor in benign breast lesions , 2000, Journal of clinical pathology.

[128]  A. Bankfalvi,et al.  Cytokeratin 5/6 immunohistochemistry assists the differential diagnosis of atypical proliferations of the breast , 2000, Histopathology.

[129]  Christian A. Rees,et al.  Molecular portraits of human breast tumours , 2000, Nature.

[130]  J. Taubenberger,et al.  Loss of heterozygosity in fibrocystic change of the breast: genetic relationship between benign proliferative lesions and associated carcinomas. , 2000, The American journal of pathology.

[131]  R. Simon,et al.  Genetic relation of lobular carcinoma in situ, ductal carcinoma in situ, and associated invasive carcinoma of the breast , 2000, Molecular pathology : MP.

[132]  G. Bratthauer,et al.  Genetic abnormalities in mammary ductal intraepithelial neoplasia‐flat type (“clinging ductal carcinoma in situ”) , 2000, Cancer.

[133]  G. Bratthauer,et al.  Concurrent and independent genetic alterations in the stromal and epithelial cells of mammary carcinoma: implications for tumorigenesis. , 2000, Cancer research.

[134]  H. Höfler,et al.  Accumulation of chromosomal imbalances from intraductal proliferative lesions to adjacent in situ and invasive ductal breast cancer. , 2000, Diagnostic molecular pathology : the American journal of surgical pathology, part B.

[135]  Denley,et al.  Metaplastic carcinoma of the breast arising within complex sclerosing lesion: a report of five cases , 2000, Histopathology.

[136]  M. Stratton,et al.  Genetic alterations in ‘normal’ luminal and myoepithelial cells of the breast , 1999, The Journal of pathology.

[137]  M. Emmert-Buck,et al.  Loss of heterozygosity is detected at chromosomes 1p35-36 (NB), 3p25 (VHL), 16p13 (TSC2/PKD1), and 17p13 (TP53) in microdissected apocrine carcinomas of the breast. , 1999, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

[138]  H Buerger,et al.  Different genetic pathways in the evolution of invasive breast cancer are associated with distinct morphological subtypes , 1999, The Journal of pathology.

[139]  H. Sasano,et al.  LOH analyses of premalignant and malignant lesions of human breast: frequent LOH in 8p, 16q, and 17q in atypical ductal hyperplasia. , 1999, Oncology reports.

[140]  A. Selim,et al.  Immunohistochemical localisation of androgen receptor in apocrine metaplasia and apocrine adenosis of the breast: relation to oestrogen and progesterone receptors. , 1999, Journal of clinical pathology.

[141]  T. Oyama,et al.  Atypical cystic lobules: an early stage in the formation of low-grade ductal carcinoma in situ , 1999, Virchows Archiv.

[142]  S. Schnitt,et al.  Lobular carcinoma in situ: current concepts and controversies. , 1999, Seminars in diagnostic pathology.

[143]  A. Hanby,et al.  Comparative genomic hybridization of breast tumors stratified by histological grade reveals new insights into the biological progression of breast cancer. , 1999, Cancer research.

[144]  C. Poremba,et al.  Comparative genomic hybridization of ductal carcinoma in situ of the breast—evidence of multiple genetic pathways , 1999, The Journal of pathology.

[145]  G. Colditz,et al.  Radial scars in benign breast-biopsy specimens and the risk of breast cancer. , 1999, The New England journal of medicine.

[146]  S. Hirohashi,et al.  der(16)t(1;16)/der(1;16) in breast cancer detected by fluorescence in situ hybridization is an indicator of better patient prognosis , 1999, Genes, chromosomes & cancer.

[147]  W. Dupont,et al.  Benign breast diseases and premalignant breast disease. , 1998, Archives of pathology & laboratory medicine.

[148]  S. Schnitt,et al.  Columnar alteration with prominent apical snouts and secretions: a spectrum of changes frequently present in breast biopsies performed for microcalcifications. , 1998, The American journal of surgical pathology.

[149]  D. Henson,et al.  Benign breast changes and the risk for subsequent breast cancer: an update of the 1985 consensus statement. Cancer Committee of the College of American Pathologists. , 1998, Archives of pathology & laboratory medicine.

[150]  B. Dutrillaux,et al.  Highly recurrent der(1;16)(q10;p10) and other 16q arm alterations in lobular breast cancer , 1998, Genes, Chromosomes and Cancer.

[151]  Yong-jie Lu,et al.  Comparative genomic hybridization analysis of lobular carcinoma in situ and atypical lobular hyperplasia and potential roles for gains and losses of genetic material in breast neoplasia. , 1998, Cancer research.

[152]  L. Cupples,et al.  Genetically abnormal clones in histologically normal breast tissue. , 1998, The American journal of pathology.

[153]  P. O’Connell,et al.  Analysis of loss of heterozygosity in 399 premalignant breast lesions at 15 genetic loci. , 1998, Journal of the National Cancer Institute.

[154]  F. Tavassoli Ductal carcinoma in situ: introduction of the concept of ductal intraepithelial neoplasia. , 1998, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

[155]  Robert F. Bonner,et al.  Laser Capture Microdissection: Molecular Analysis of Tissue , 1997, Science.

[156]  B. O'Malley,et al.  Cancerization of small ectatic ducts of the breast by ductal carcinoma in situ cells with apocrine snouts: a lesion associated with tubular carcinoma. , 1997, American journal of clinical pathology.

[157]  M. J. van de Vijver,et al.  © 1997 Cancer Research Campaign , 2022 .

[158]  A. Thor,et al.  Loss of Heterozygosity in Normal Tissue Adjacent to Breast Carcinomas , 1996, Science.

[159]  H. Smith,et al.  Contiguous patches of normal human mammary epithelium derived from a single stem cell: implications for breast carcinogenesis. , 1996, Cancer research.

[160]  M. Stratton,et al.  Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations. , 1996, Laboratory investigation; a journal of technical methods and pathology.

[161]  W. Dupont,et al.  Papillary apocrine change of the breast: associations with atypical hyperplasia and risk of breast cancer. , 1996, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[162]  M. Stratton,et al.  Atypical ductal hyperplasia of the breast: clonal proliferation with loss of heterozygosity on chromosomes 16q and 17p. , 1995, Journal of clinical pathology.

[163]  M. Stratton,et al.  Loss of heterozygosity in lobular carcinoma in situ of the breast , 1995, Clinical molecular pathology.

[164]  M. Stratton,et al.  Loss of heterozygosity in ductal carcinoma in situ of the breast , 1995, The Journal of pathology.

[165]  V. Eusebi,et al.  Microglandular Adenosis of The Breast , 1995 .

[166]  J. Sloane,et al.  Carcinoma and atypical hyperplasia in radial scars and complex sclerosing lesions: importance of lesion size and patient age , 1993, Histopathology.

[167]  C. Bodian,et al.  Prognostic significance of benign proliferative breast disease , 1993, Cancer.

[168]  G. Bratthauer,et al.  Immunohistochemical profile and differential diagnosis of microglandular adenosis. , 1993, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

[169]  L. Brinton,et al.  Breast cancer risk associated with proliferative breast disease and atypical hyperplasia , 1993, Cancer.

[170]  W. Dupont,et al.  Diagnostic criteria and cancer risk of proliferative breast lesions , 1993, Journal of cellular biochemistry. Supplement.

[171]  N. Weidner,et al.  Pleomorphic variant of invasive lobular carcinoma of the breast. , 1992, Human pathology.

[172]  V. Eusebi,et al.  Pleomorphic lobular carcinoma of the breast: an aggressive tumor showing apocrine differentiation. , 1992, Human pathology.

[173]  W. Dupont,et al.  Indicators of increased breast cancer risk in humans , 1992, Journal of cellular biochemistry. Supplement.

[174]  R. Kempson,et al.  In situ proliferative epithelial lesions of the breast. , 1992, Pathology.

[175]  W. Dupont,et al.  Anatomic markers of human premalignancy and risk of breast cancer , 1990, Cancer.

[176]  F. Tavassoli,et al.  A comparison of the results of long‐term follow‐up for atypical intraductal hyperplasia and intraductal hyperplasia of the breast , 1990, Cancer.

[177]  Y. Nakamura,et al.  Genetic alterations during colorectal-tumor development. , 1988, The New England journal of medicine.

[178]  W. Dupont,et al.  Ductal involvement by cells of atypical lobular hyperplasia in the breast: a long-term follow-up study of cancer risk. , 1988, Human pathology.

[179]  M. Nielsen,et al.  Radial scars in women with breast cancer , 1987, Cancer.

[180]  M. Rosenblum,et al.  Is Microglandular Adenosis a Precancerous Disease?: A Study of Carcinoma Arising Therein , 1986, The American journal of surgical pathology.

[181]  W. Dupont,et al.  Atypical hyperplastic lesions of the female breast: A long-term follow-up study , 1986 .

[182]  T. Anderson,et al.  Radial scars of benign and malignant breasts: Comparative features and significance , 1985, The Journal of pathology.

[183]  David L. Page,et al.  Atypical hyperplastic lesions of the female breast. A long‐term follow‐up study , 1985, Cancer.

[184]  W D Dupont,et al.  Risk factors for breast cancer in women with proliferative breast disease. , 1985, The New England journal of medicine.

[185]  J. Andersen,et al.  Radial scar in the female breast. A long‐term follow‐up study of 32 cases , 1984, Cancer.

[186]  F. Tavassoli,et al.  Microglandular adenosis of the breast: A clinicopathologic study of 11 cases with ultrastructural observations* , 1983, The American journal of surgical pathology.

[187]  P. Clement,et al.  Microglandular adenosis of the breast—a lesion simulating tubular carcinoma , 1983, Histopathology.

[188]  P. Rosen Microglandular adenosis: A benign lesion simulating invasive mammary carcinoma , 1983, The American journal of surgical pathology.

[189]  W. Dupont,et al.  Intraductal carcinoma of the breast: Follow‐up after biopsy only , 1982, Cancer.

[190]  B. Jones,et al.  The presentation and progress of macroscopic breast cysts , 1980, The British journal of surgery.

[191]  E. Fisher,et al.  A nonencapsulated sclerosing lesion of the breast. , 1979, American journal of clinical pathology.

[192]  C. Bodian,et al.  Lobular neoplasia (so‐called lobular carcinoma in situ) of the breast , 1978, Cancer.

[193]  H M Jensen,et al.  An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions. , 1975, Journal of the National Cancer Institute.

[194]  H M Jensen,et al.  On the origin and progression of ductal carcinoma in the human breast. , 1973, Journal of the National Cancer Institute.

[195]  S. Wellings,et al.  Organ cultures of normal, dysplastic, hyperplastic, and neoplastic human mammary tissues. , 1972, Journal of the National Cancer Institute.

[196]  A. Templeton,et al.  Tumours of the Breast , 1894, The Hospital.