Coffee prevents IQ-induced liver damage by regulating oxidative stress, inflammation, endoplasmic reticulum stress, autophagy, apoptosis, and the MAPK/NF-κB signaling pathway in zebrafish.

[1]  Erdong Yuan,et al.  Shibi Tea (Adinandra nitida) and Camellianin A Alleviate CCl4-Induced Liver Injury in C57BL-6J Mice by Attenuation of Oxidative Stress, Inflammation, and Apoptosis , 2022, Nutrients.

[2]  Shuyi Zhang,et al.  The Impact of Instant Coffee and Decaffeinated Coffee on the Gut Microbiota and Depression-Like Behaviors of Sleep-Deprived Rats , 2022, Frontiers in Microbiology.

[3]  Yang Zhang,et al.  Effect of Coffee against MPTP-Induced Motor Deficits and Neurodegeneration in Mice Via Regulating Gut Microbiota. , 2022, Journal of agricultural and food chemistry.

[4]  OUP accepted manuscript , 2022, European Journal of Preventive Cardiology.

[5]  Z. Zuo,et al.  Induction of autophagy via the ROS-dependent AMPK-mTOR pathway protects copper-induced spermatogenesis disorder , 2021, Redox biology.

[6]  Fan Mo,et al.  Crosstalk between Endoplasmic Reticulum Stress and Oxidative Stress in Heat Exposure-Induced Apoptosis Is Dependent on the ATF4-CHOP-CHAC1 Signal Pathway in IPEC-J2 Cells. , 2021, Journal of agricultural and food chemistry.

[7]  F. Kandemir,et al.  Investigation of the effects of hesperidin administration on abamectin‐induced testicular toxicity in rats through oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, autophagy, and JAK2/STAT3 pathways , 2021, Environmental Toxicology.

[8]  Shuo Wang,et al.  2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio) , 2021, Toxins.

[9]  S. F. Arruda,et al.  The effect of coffee consumption on glucose homeostasis and redox-inflammatory responses in high-fat diet-induced obese rats. , 2021, The Journal of nutritional biochemistry.

[10]  Daoying Wang,et al.  Heterocyclic amines in cooked meat products, shortcomings during evaluation, factors influencing formation, risk assessment and mitigation strategies. , 2021, Meat science.

[11]  Chengtao Wang,et al.  Cyanidin-3-O-glucoside and its metabolite protocatechuic acid ameliorate 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced cytotoxicity in HepG2 cells by regulating apoptotic and Nrf2/p62 pathways. , 2021, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[12]  Hongwen Sun,et al.  2-Amino-3-methylimidazo[4,5-f]quinoline induced oxidative stress and inflammation via TLR4/MAPK and TLR4/NF-κB signaling pathway in zebrafish (Danio rerio) livers. , 2021, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[13]  Lianbo Xiao,et al.  Trigonelline, An Alkaloid From Leonurus japonicus Houtt., Suppresses Mast Cell Activation and OVA-Induced Allergic Asthma , 2021, Frontiers in Pharmacology.

[14]  Peipei Cao,et al.  Long-term exposure to 2-amino-3-methylimidazo[4,5-f]quinoline can trigger a potential risk of Parkinson's disease. , 2021, Journal of hazardous materials.

[15]  Dai Cheng,et al.  Protection Mechanisms Underlying Oral Administration of Chlorogenic Acid against Cadmium-Induced Hepatorenal Injury Related to Regulating Intestinal Flora Balance. , 2021, Journal of agricultural and food chemistry.

[16]  H. Randeva,et al.  Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE(-/-) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis , 2021, International journal of molecular sciences.

[17]  H. Merzouk,et al.  Free radicals and coffee polyphenols: Potential applications in toxicity , 2021 .

[18]  Bailiang Li,et al.  Lactobacillus plantarum KLDS1.0344 and Lactobacillus acidophilus KLDS1.0901 Mixture Prevents Chronic Alcoholic Liver Injury in Mice by Protecting the Intestinal Barrier and Regulating Gut Microbiota and Liver-Related Pathways. , 2020, Journal of agricultural and food chemistry.

[19]  Peter Dellatore,et al.  Inverse Association of Coffee with Liver Cancer Development: An Updated Systematic Review and Meta-analysis. , 2020, Journal of gastrointestinal and liver diseases : JGLD.

[20]  Lijun Pang,et al.  Asiatic acid ameliorates acute hepatic injury by reducing endoplasmic reticulum stress and triggering hepatocyte autophagy. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[21]  Y. Xiang,et al.  Diet and liver cancer risk: a narrative review of epidemiological evidence , 2020, British Journal of Nutrition.

[22]  Wanjing Liu,et al.  Microcystin-LR triggers different endoplasmic reticulum stress pathways in the liver, ovary, and offspring of zebrafish (Danio rerio). , 2019, Journal of hazardous materials.

[23]  L. Teh,et al.  Aqueous Partition of Methanolic Extract of Dicranopteris linearis Leaves Protects against Liver Damage Induced by Paracetamol , 2019, Nutrients.

[24]  G. Zheng,et al.  Collaborative effects of chlorogenic acid and caffeine on lipid metabolism via the AMPKα-LXRα/SREBP-1c pathway in high-fat diet-induced obese mice. , 2019, Food & function.

[25]  J. Rochet,et al.  Neuromelanin modulates heterocyclic aromatic amine-induced dopaminergic neurotoxicity. , 2019, Toxicological sciences : an official journal of the Society of Toxicology.

[26]  M. Vinken,et al.  Drinking for protection? Epidemiological and experimental evidence on the beneficial effects of coffee or major coffee compounds against gastrointestinal and liver carcinogenesis. , 2019, Food research international.

[27]  Yuliang Cheng,et al.  Torularhodin Ameliorates Oxidative Activity in Vitro and D-galactose-induced Liver Injury via the Nrf2/HO-1 Signaling Pathway in Vivo. , 2019, Journal of agricultural and food chemistry.

[28]  R. Sinha,et al.  Prospective investigation of serum metabolites, coffee drinking, liver cancer incidence, and liver disease mortality. , 2019, Journal of the National Cancer Institute.

[29]  Weiming Zhao,et al.  Caffeine Inhibits NLRP3 Inflammasome Activation by Suppressing MAPK/NF-κB and A2aR Signaling in LPS-Induced THP-1 Macrophages , 2019, International journal of biological sciences.

[30]  Lanjuan Li,et al.  Tectorigenin protects against experimental fulminant hepatic failure by regulating the TLR4/mitogen‐activated protein kinase and TLR4/nuclear factor‐κB pathways and autophagy , 2019, Phytotherapy research : PTR.

[31]  A. Luchiari,et al.  Coffee time: Low caffeine dose promotes attention and focus in zebrafish , 2019, Learning & behavior.

[32]  S. Chao,et al.  Potential nutraceutical and food additive properties and risks of coffee: a comprehensive overview , 2019, Critical reviews in food science and nutrition.

[33]  Jichao Huang,et al.  Occurrence of Heterocyclic Amines in Commercial Fast-Food Meat Products Available on the Chinese Market and Assessment of Human Exposure to these Compounds. , 2019, Journal of food science.

[34]  Samuel Ayofemi Olalekan Adeyeye.  Heterocyclic Amines and Polycyclic Aromatic Hydrocarbons in Cooked Meat Products: A Review , 2018, Polycyclic Aromatic Compounds.

[35]  Diana Anderson,et al.  DNA damage protection by bulk and nano forms of quercetin in lymphocytes of patients with chronic obstructive pulmonary disease exposed to the food mutagen 2‐amino‐3‐methylimidazo [4,5‐f]quinolone (IQ) , 2018, Environmental research.

[36]  R. Knott,et al.  Trigonelline prevents high cholesterol and high fat diet induced hepatic lipid accumulation and lipo-toxicity in C57BL/6J mice, via restoration of hepatic autophagy. , 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[37]  Won‐Kyo Jung,et al.  Anti‐inflammatory effect of Apo‐9′‐fucoxanthinone via inhibition of MAPKs and NF‐kB signaling pathway in LPS‐stimulated RAW 264.7 macrophages and zebrafish model , 2018, International immunopharmacology.

[38]  H. A. El-Bakry,et al.  Therapeutic dose of green tea extract provokes liver damage and exacerbates paracetamol-induced hepatotoxicity in rats through oxidative stress and caspase 3-dependent apoptosis. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[39]  A. Luchiari,et al.  Caffeine Dose-Response Relationship and Behavioral Screening in Zebrafish , 2017 .

[40]  G. Li Volti,et al.  Molecular Bases Underlying the Hepatoprotective Effects of Coffee , 2017, Nutrients.

[41]  Kui-Jin Kim,et al.  Caffeine prevents LPS-induced inflammatory responses in RAW264.7 cells and zebrafish. , 2016, Chemico-biological interactions.

[42]  Kunyuan Wang,et al.  Caffeine reduces hepatic lipid accumulation through regulation of lipogenesis and ER stress in zebrafish larvae , 2015, Journal of Biomedical Science.

[43]  R. Peralta,et al.  Green tea extract improves the oxidative state of the liver and brain in rats with adjuvant-induced arthritis. , 2015, Food & function.

[44]  B. Hong,et al.  Synergistic Potentials of Coffee on Injured Pancreatic Islets and Insulin Action via KATP Channel Blocking in Zebrafish. , 2015, Journal of agricultural and food chemistry.

[45]  Cheng-chen Huang,et al.  Reversible neuronal and muscular toxicity of caffeine in developing vertebrates. , 2014, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

[46]  B. Bay,et al.  Caffeine stimulates hepatic lipid metabolism by the autophagy‐lysosomal pathway in mice , 2014, Hepatology.

[47]  Eun Ha Lee,et al.  Chlorogenic acid and coffee prevent hypoxia-induced retinal degeneration. , 2014, Journal of agricultural and food chemistry.

[48]  T. Hase,et al.  Coffee polyphenols exert hypocholesterolemic effects in zebrafish fed a high-cholesterol diet , 2013, Nutrition & Metabolism.

[49]  Anne Constable,et al.  The effects of coffee on enzymes involved in metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats. , 2003, Chemico-biological interactions.

[50]  U. Thorgeirsson,et al.  Chemical carcinogenesis studies in nonhuman primates. , 2008, Basic life sciences.