[Depression and HAART adherence in HIV infected patients attending Hospital San Pablo of Coquimbo, Chile].

Despite the good HAART coverage of HIV infected patients in Chile, treatment success is interfered by patient-adherence problems. Moreover, HIV and depression co-morbidity has been shown to impair self-care and medication adherence. With the aim to analyze adherence problems and its relationship with depression in HIV infected patients, we evaluated 119 HIV infected patients, attending Coquimbo's Hospital. Our sample was incidental and transversally evaluated with: Morisky, Green & Levine Medication Adherence Scale, and the Beck - II Depression Inventory. In addition, demographic and health data were obtained from clinical files. Main results showed that 68% patients referred having HAART adherence problems, with differences in sex, age and treatment duration. Logistic regression analysis showed that patients with moderate-severe depressive symptoms have 3,08 (95% IC 1,08-8,80) times higher risk of having adherence problems compared to patients with mild to no depressive symptoms.

[1]  Alexis K. Huynh,et al.  The role of mental health in mediating the relationship between social support and optimal ART adherence , 2013, AIDS care.

[2]  Richard D Moore,et al.  The impact of depressive symptoms on patient–provider communication in HIV care , 2013, AIDS care.

[3]  J. Levy,et al.  HIV-related symptoms and patient clusters among Chileans living with HIV , 2013, AIDS care.

[4]  A. Bulgiba,et al.  How well does self-reported adherence fare compared to therapeutic drug monitoring in HAART? , 2013, Preventive medicine.

[5]  Stacey B. Daughters,et al.  ACT HEALTHY: A Combined Cognitive-Behavioral Depression and Medication Adherence Treatment for HIV-Infected Substance Users. , 2010, Cognitive and behavioral practice.

[6]  V. Hosegood,et al.  “No one can ask me ‘Why do you take that stuff?’”: men's experiences of antiretroviral treatment in South Africa , 2010, AIDS care.

[7]  E. Eng,et al.  Factors associated with self-reported adherence to antiretroviral therapy in a Tanzanian setting , 2010, AIDS care.

[8]  L. ClaudiaWolff,et al.  [Depression in HIV infection: prevalence, risk factors and management] , 2010 .

[9]  Luis Xochihua-Díaz.  Apego al tratamiento antirretroviral en adolescentes , 2009 .

[10]  R. Remien,et al.  Anxiety and Depression Symptoms as Risk Factors for Non-adherence to Antiretroviral Therapy in Brazil , 2010, AIDS and Behavior.

[11]  I. Miller,et al.  Integrating co-morbid depression and chronic physical disease management: identifying and resolving failures in self-regulation. , 2008, Clinical psychology review.

[12]  Cristina Herrera,et al.  Relação entre médicos e pacientes com HIV: influência na adesão terapêutica e qualidade de vida , 2008 .

[13]  E. B. Pineda,et al.  Metodología de la investigación , 2008 .

[14]  A. Malbergier,et al.  Depression in women infected with HIV. , 2006, Revista brasileira de psiquiatria.

[15]  Carmelo Vázquez Valverde,et al.  Adaptación española del inventario para la depresión de Beck-II (BDI-II) : 1 : propiedades psicométricas en estudiantes universitarios , 2003 .

[16]  M. Galindo,et al.  Recomendaciones GESIDA/SEFH/PNS para mejorar la adherencia al tratamiento antirretroviral en el año 2004 , 1999 .

[17]  L. Green,et al.  Concurrent and Predictive Validity of a Self-reported Measure of Medication Adherence , 1986, Medical care.