This paper proposes a new discipline with hybrid methodology mixing traditional approach and Project Based Learning, using some active learning techniques as peer instruction to teach Human Factors and Usability. This course will be offered in Federal University of Itajuba for undergrad students in Computer Sciences, Information System, Computer Engineering, Control and Automation Engineering, Electronic Engineering and Industrial Engineering. The dynamics of the classes will be guided by working in teams of students and tutoring in the proposed PBL themes. Some formal lectures about specific concepts and methods throughout the development and analysis of the proposed problems will also be held. It is expected to have a greater conceptual gain with a higher engagement by students. To evaluate the student achievement, an assessment will be applied to the end of the course, targeting both the knowledge gain and the student’s motivation.