Physiological and molecular analysis of the stress response of Saccharomyces cerevisiae imposed by strong inorganic acid with implication to industrial fermentations

Aims:  This work aimed to identify the molecular mechanism that allows yeast cells to survive at low pH environments such as those of bioethanol fermentation.

[1]  S. Blad,et al.  Low external pH induces HOG1‐dependent changes in the organization of the Saccharomyces cerevisiae cell wall , 2001, Molecular microbiology.

[2]  J. François,et al.  Physiological behaviour of Saccharomyces cerevisiae in aerated fed-batch fermentation for high level production of bioethanol. , 2007, FEMS yeast research.

[3]  Audrey P. Gasch,et al.  The environmental stress response: a common yeast response to diverse environmental stresses , 2003 .

[4]  A. Querol,et al.  Analysis of the stress resistance of commercial wine yeast strains , 2001, Archives of Microbiology.

[5]  P. Piper,et al.  Screening the yeast deletant mutant collection for hypersensitivity and hyper‐resistance to sorbate, a weak organic acid food preservative , 2004, Yeast.

[6]  W. H. Mager,et al.  Glucose-triggered signalling in Saccharomyces cerevisiae: different requirements for sugar phosphorylation between cells grown on glucose and those grown on non-fermentable carbon sources. , 1996, Microbiology.

[7]  D. Botstein,et al.  Genomic expression programs in the response of yeast cells to environmental changes. , 2000, Molecular biology of the cell.

[8]  A. Covarrubias,et al.  Response to different environmental stress conditions of industrial and laboratory Saccharomyces cerevisiae strains , 2004, Applied Microbiology and Biotechnology.

[9]  M. Skoneczny,et al.  Saccharomyces cerevisiae Hsp31p, a stress response protein conferring protection against reactive oxygen species. , 2007, Free radical biology & medicine.

[10]  G. Santangelo,et al.  Glucose Signaling in Saccharomyces cerevisiae , 2006, Microbiology and Molecular Biology Reviews.

[11]  B. Gibson,et al.  Yeast responses to stresses associated with industrial brewery handling. , 2007, FEMS microbiology reviews.

[12]  Naren Ramakrishnan,et al.  Transcriptional Response of Saccharomyces cerevisiae to Desiccation and Rehydration , 2005, Applied and Environmental Microbiology.

[13]  P. R. de Araujo,et al.  Detection and Identification of Wild Yeast Contaminants of the Industrial Fuel Ethanol Fermentation Process , 2008, Current Microbiology.

[14]  I. Sá-Correia,et al.  Modification of Saccharomyces cerevisiae thermotolerance following rapid exposure to acid stress. , 1998, International journal of food microbiology.

[15]  C. Gil,et al.  Transcriptomic and Proteomic Approach for Understanding the Molecular Basis of Adaptation of Saccharomyces cerevisiae to Wine Fermentation , 2006, Applied and Environmental Microbiology.

[16]  Christophe Junot,et al.  Combined Proteome and Metabolite-profiling Analyses Reveal Surprising Insights into Yeast Sulfur Metabolism* , 2005, Journal of Biological Chemistry.

[17]  J. Thevelein,et al.  Nutrient sensing systems for rapid activation of the protein kinase A pathway in yeast. , 2005, Biochemical Society transactions.

[18]  A. Goffeau,et al.  Regulation of pleiotropic drug resistance in yeast. , 1999, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

[19]  Audrey P Gasch,et al.  Stress-activated genomic expression changes serve a preparative role for impending stress in yeast. , 2008, Molecular biology of the cell.

[20]  J. C. Kapteyn,et al.  The contribution of cell wall proteins to the organization of the yeast cell wall. , 1999, Biochimica et biophysica acta.

[21]  J. De Morais,et al.  Yeast population dynamics of industrial fuel-ethanol fermentation process assessed by PCR-fingerprinting , 2005, Antonie van Leeuwenhoek.

[22]  H. Shimizu,et al.  Comparative analysis of transcriptional responses to saline stress in the laboratory and brewing strains of Saccharomyces cerevisiae with DNA microarray , 2006, Applied Microbiology and Biotechnology.

[23]  K. Masaki,et al.  Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. , 2006, FEMS yeast research.

[24]  Y. Chae,et al.  Acquisition of heat shock tolerance by regulation of intracellular redox states. , 2003, Biochimica et biophysica acta.

[25]  S. Colombo,et al.  A baker's yeast mutant (fil1) with a specific, partially inactivating mutation in adenylate cyclase maintains a high stress resistance during active fermentation and growth. , 2000, Journal of molecular microbiology and biotechnology.

[26]  T. James,et al.  The stress response is repressed during fermentation in brewery strains of yeast , 2000, Journal of applied microbiology.

[27]  M. A. de Morais Jr,et al.  Isolation by genetic and physiological characteristics of a fuel-ethanol fermentative Saccharomyces cerevisiae strain with potential for genetic manipulation , 2005, Journal of Industrial Microbiology and Biotechnology.

[28]  J. François,et al.  Effects of heat shock on the level of trehalose and glycogen, and on the induction of thermotolerance in Neurospora crassa , 1991, FEBS letters.

[29]  H. Tamaki.  Glucose-stimulated cAMP-protein kinase A pathway in yeast Saccharomyces cerevisiae. , 2007, Journal of bioscience and bioengineering.