A Method of Bio-tissue Hardness Measurement by Force Sensor-less Organ Palpation Device

Palpation is a kind of fundamental method for detecting abnormal tissue. It is known as minimally invasive and easy method. However, palpation cannot measure the hardness of bio tissue quantitatively. In order to achieve quantitative palpation, this research proposes force sensor-less palpating method. The advantage of proposal method is to be able to measure bio tissue without considering the space for the force sensor. Therefore, it is possible to measure in narrow area. Validity of the proposed device is confirmed by the animal experiment.

[1]  Chao Liu,et al.  Viscoelastic model based force control for soft tissue interaction and its application in physiological motion compensation , 2014, Comput. Methods Programs Biomed..

[2]  Kouhei Ohnishi,et al.  Proposal of friction and force transmission compensator for cancer hardness measurement system using flexible actuator , 2014, 2014 IEEE 23rd International Symposium on Industrial Electronics (ISIE).

[3]  P. Devitt,et al.  Palpation as a useful diagnostic tool for skin lesions. , 2014, Journal of plastic, reconstructive & aesthetic surgery : JPRAS.

[4]  Pietro Valdastri,et al.  Wireless Tissue Palpation for Intraoperative Detection of Lumps in the Soft Tissue , 2014, IEEE Transactions on Biomedical Engineering.

[5]  A. Alberti,et al.  How far is noninvasive assessment of liver fibrosis from replacing liver biopsy in hepatitis C? , 2012, Journal of viral hepatitis.

[6]  M. Charbit,et al.  Fibroscan® practice improvement with a real-time assistance ultrasound tool: a premiminary study , 2009, 2009 IEEE International Ultrasonics Symposium.

[7]  Todd E. Zickler,et al.  Constitutive modeling of porcine liver in indentation using 3D ultrasound imaging. , 2009, Journal of the mechanical behavior of biomedical materials.

[8]  O A Lindahl,et al.  Tactile resonance sensors in medicine , 2009, Journal of medical engineering & technology.

[9]  T. Furukawa,et al.  Free allocation of actuator against end-effector by using flexible actuator , 2006, 9th IEEE International Workshop on Advanced Motion Control, 2006..

[10]  P. Shi,et al.  Liver fibrosis identification based on ultrasound images captured under varied imaging protocols. , 2005, Journal of Zhejiang University. Science. B.

[11]  Humberto Breves Coda,et al.  A simple Kelvin and Boltzmann viscoelastic analysis of three-dimensional solids by the boundary element method , 2003 .

[12]  K. Chihara,et al.  Shear Modulus and Viscosity Measurement Using MR Elastography , 2001 .

[13]  Kouhei Ohnishi,et al.  Robust Motion Control by Disturbance Observer , 1993, J. Robotics Mechatronics.

[14]  Toshiyuki Murakami,et al.  Torque sensorless control in multidegree-of-freedom manipulator , 1993, IEEE Trans. Ind. Electron..

[15]  Kouhei Ohnishi,et al.  Verification of Flexible Actuator From Position and Force Transfer Characteristic and Its Application to Bilateral Teleoperation System , 2009, IEEE Transactions on Industrial Electronics.

[16]  M. Kaneko,et al.  Non-contact stiffness imager for medical application , 2005, 2005 IEEE International Conference on Information Acquisition.

[17]  J. Bruzzi,et al.  Liver biopsy. , 2001, The New England journal of medicine.

[18]  J. J. Moré,et al.  Levenberg--Marquardt algorithm: implementation and theory , 1977 .