Broadband spectroscopy of dynamic impedances with short chirp pulses

An impedance spectrum of dynamic systems is time dependent. Fast impedance changes take place, for example, in high throughput microfluidic devices and in operating cardiovascular systems. Measurements must be as short as possible to avoid significant impedance changes during the spectrum analysis, and as long as possible for enlarging the excitation energy and obtaining a better signal-to-noise ratio (SNR). The authors propose to use specific short chirp pulses for excitation. Thanks to the specific properties of the chirp function, it is possible to meet the needs for a spectrum bandwidth, measurement time and SNR so that the most accurate impedance spectrogram can be obtained. The chirp wave excitation can include thousands of cycles when the impedance changes slowly, but in the case of very high speed changes it can be shorter than a single cycle, preserving the same excitation bandwidth. For example, a 100 kHz bandwidth can be covered by the chirp pulse with durations from 10 µs to 1 s; only its excitation energy differs also 10(5) times. After discussing theoretical short chirp properties in detail, the authors show how to generate short chirps in the microsecond range with a bandwidth up to a few MHz by using digital synthesis architectures developed inside a low-cost standard field programmable gate array.

[1]  E. Gersing,et al.  Evaluation of Fast Time-domain Based Impedance Measurements on Biological Tissue - Beurteilung schneller Impedanzmessungen im Zeitbereich an biologischen Geweben , 2000, Biomedizinische Technik. Biomedical engineering.

[2]  Roland Zengerle,et al.  Real-time cannula navigation in biological tissue with high temporal and spatial resolution based on impedance spectroscopy , 2010, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology.

[3]  T. J. Endres,et al.  Design and analysis methods of a DDS-based synthesizer for military spaceborne applications , 1994, Proceedings of IEEE 48th Annual Symposium on Frequency Control.

[4]  Paul Annus,et al.  Broadband spectroscopy of a dynamic impedance , 2010 .

[5]  Paul Annus,et al.  Signals in bioimpedance measurement: different waveforms for different tasks , 2007 .

[6]  M Min,et al.  Broadband excitation for short-time impedance spectroscopy , 2008, Physiological measurement.

[7]  Manoochehr Nahvi,et al.  Wideband electrical impedance tomography , 2008 .

[8]  Svetozar S. Broussev,et al.  A Wideband Low Phase-Noise LC-VCO With Programmable $K_{\rm VCO}$ , 2007, IEEE Microwave and Wireless Components Letters.

[9]  A. T. Giannitsis,et al.  Comparison of Rectangular Wave Excitations in Broad Band Impedance Spectroscopy for Microfluidic Applications , 2009 .

[10]  Byung-Sung Kim,et al.  Programmable active inductor-based wideband VCO/QVCO design , 2008 .

[11]  Antonio Corradi,et al.  A DDS-compliant infrastructure for fault-tolerant and scalable data dissemination , 2010, The IEEE symposium on Computers and Communications.

[12]  Paul Annus,et al.  Synchronous Sampling and Demodulation in an Instrument for Multifrequency Bioimpedance Measurement , 2007, IEEE Transactions on Instrumentation and Measurement.

[13]  Mart Min,et al.  Short-time chirp excitations for using in wideband characterization of objects: An overview , 2010, 2010 12th Biennial Baltic Electronics Conference.

[14]  A. Willson,et al.  Exact analysis of DDS spurs and SNR due to phase truncation and arbitrary phase-to-amplitude errors , 2005, Proceedings of the 2005 IEEE International Frequency Control Symposium and Exposition, 2005..

[15]  J. Vankka Methods of mapping from phase to sine amplitude in direct digital synthesis , 1997, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[16]  Hywel Morgan,et al.  Digital signal processing methods for impedance microfluidic cytometry , 2009 .

[17]  M. Nahvi,et al.  Electrical Impedance Spectroscopy Sensing for Industrial Processes , 2009, IEEE Sensors Journal.