论文信息 - Association of hormonal contraception and HIV-seroprevalence in Nairobi, Kenya

Association of hormonal contraception and HIV-seroprevalence in Nairobi, Kenya

Among women attending family planning clinics in Nairobi, Kenya, the HIV-seroprevalence rates for different contraceptive methods were: depomedroxyprogesterone acetate (DMPA) 431/3279 (13.1%), combination oral contraceptive pill 114/1073 (10.6%), and progesterone-only contraceptive pill (POCP) 45/741 (6.1%). After adjusting for age, marital status, and parity, women using the POCP had a lower HIV seroprevalence (adjusted odds ratio 0.5, 95% confidence interval 0.3-0.7) than women using DMPA. This association was most pronounced among POCP users of lower parity.

[1] B. Levy,et al. Magnitude and variability of sequential estradiol and progesterone concentrations in women using depot medroxyprogesterone acetate for contraception. , 2001, Fertility and sterility.

[2] P. Marx,et al. Estrogen protects against vaginal transmission of simian immunodeficiency virus. , 2000, The Journal of infectious diseases.

[3] B. Richardson,et al. Hormonal contraception, sexually transmitted diseases, and risk of heterosexual transmission of human immunodeficiency virus type 1. , 1998, The Journal of infectious diseases.