STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells

[1]  P. van Endert,et al.  UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells , 2017, Nature Communications.

[2]  Joel Babdor,et al.  IRAP+ endosomes restrict TLR9 activation and signaling , 2017, Nature Immunology.

[3]  C. Porta,et al.  Targeting Stim and Orai Proteins as an Alternative Approach in Anticancer Therapy. , 2016, Current medicinal chemistry.

[4]  Robert V Farese,et al.  Taming the sphinx: Mechanisms of cellular sphingolipid homeostasis. , 2016, Biochimica et biophysica acta.

[5]  N. Demaurex,et al.  The role of STIM and ORAI proteins in phagocytic immune cells , 2016, American journal of physiology. Cell physiology.

[6]  S. Feske,et al.  Selective ORAI1 Inhibition Ameliorates Autoimmune Central Nervous System Inflammation by Suppressing Effector but Not Regulatory T Cell Function , 2016, The Journal of Immunology.

[7]  K. Gevaert,et al.  Toll-like Receptor 4 Engagement on Dendritic Cells Restrains Phago-Lysosome Fusion and Promotes Cross-Presentation of Antigens. , 2015, Immunity.

[8]  N. Demaurex,et al.  Measuring Phagosome pH by Ratiometric Fluorescence Microscopy. , 2015, Journal of visualized experiments : JoVE.

[9]  Albert S. Yu,et al.  Identification of key amino acid residues responsible for internal and external pH sensitivity of Orai1/STIM1 channels , 2015, Scientific Reports.

[10]  S. Feske,et al.  Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells , 2015, The Journal of Immunology.

[11]  D. Agrawal,et al.  Intermediate-conductance calcium-activated potassium channel KCa3.1 and chloride channel modulate chemokine ligand (CCL19/CCL21)-induced migration of dendritic cells. , 2015, Translational research : the journal of laboratory and clinical medicine.

[12]  A. Erdei,et al.  Syk is indispensable for CpG-induced activation and differentiation of human B cells , 2015, Cellular and Molecular Life Sciences.

[13]  A. Koster,et al.  The translocon protein Sec61 mediates antigen transport from endosomes in the cytosol for cross-presentation to CD8(+) T cells. , 2015, Immunity.

[14]  P. Hogan,et al.  Store-operated calcium entry: Mechanisms and modulation. , 2015, Biochemical and biophysical research communications.

[15]  I. Nonaka,et al.  Dominant mutations in ORAI1 cause tubular aggregate myopathy with hypocalcemia via constitutive activation of store-operated Ca²⁺ channels. , 2015, Human molecular genetics.

[16]  R. Tampé,et al.  TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation , 2014, Cell.

[17]  J. Saurat,et al.  Reversal of murine epidermal atrophy by topical modulation of calcium signaling. , 2014, The Journal of investigative dermatology.

[18]  N. Demaurex,et al.  Hv1 proton channels differentially regulate the pH of neutrophil and macrophage phagosomes by sustaining the production of phagosomal ROS that inhibit the delivery of vacuolar ATPases , 2014, Journal of leukocyte biology.

[19]  P. Hogan,et al.  ORAI1 calcium channel orchestrates skin homeostasis , 2013, Proceedings of the National Academy of Sciences.

[20]  M. Dinauer,et al.  Regulation of the NADPH Oxidase and Associated Ion Fluxes During Phagocytosis , 2013, Traffic.

[21]  T. van Hall,et al.  Importance of TAP-independent processing pathways. , 2013, Molecular immunology.

[22]  M. Podinovskaia,et al.  Dynamic Quantitative Assays of Phagosomal Function , 2013, Current protocols in immunology.

[23]  A. Delalande,et al.  The Orai-1 and STIM-1 Complex Controls Human Dendritic Cell Maturation , 2013, PloS one.

[24]  Miriam Merad,et al.  The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. , 2013, Annual review of immunology.

[25]  B. Freedman,et al.  Spleen Tyrosine Kinase (Syk)-dependent Calcium Signals Mediate Efficient CpG-induced Exocytosis of Tumor Necrosis Factor α (TNFα) in Innate Immune Cells* , 2013, The Journal of Biological Chemistry.

[26]  Fiorella Kotsias,et al.  Reactive oxygen species production in the phagosome: impact on antigen presentation in dendritic cells. , 2013, Antioxidants & redox signaling.

[27]  M. Boes,et al.  Fcγ receptor antigen targeting potentiates cross-presentation by human blood and lymphoid tissue BDCA-3+ dendritic cells. , 2012, Blood.

[28]  N. Demaurex,et al.  STIM1 Juxtaposes ER to Phagosomes, Generating Ca2+ Hotspots that Boost Phagocytosis , 2012, Current Biology.

[29]  P. Thibault,et al.  Quantitative Proteomics Reveals That Only a Subset of the Endoplasmic Reticulum Contributes to the Phagosome* , 2012, Molecular & Cellular Proteomics.

[30]  R. Yates,et al.  Phagosomal proteolysis in dendritic cells is modulated by NADPH oxidase in a pH‐independent manner , 2012, The EMBO journal.

[31]  N. Demaurex,et al.  Morphological and functional aspects of STIM1-dependent assembly and disassembly of store-operated calcium entry complexes. , 2012, Biochemical Society transactions.

[32]  J. Enninga,et al.  Sec22b Regulates Phagosomal Maturation and Antigen Crosspresentation by Dendritic Cells , 2011, Cell.

[33]  C. Melchior,et al.  An Essential Role of STIM1, Orai1, and S100A8–A9 Proteins for Ca2+ Signaling and FcγR-Mediated Phagosomal Oxidative Activity , 2011, The Journal of Immunology.

[34]  A. Tlili,et al.  Kinetic analysis of phagosomal production of reactive oxygen species. , 2011, Free radical biology & medicine.

[35]  S. Pingle,et al.  Store‐operated Ca2+ signaling in dendritic cells occurs independently of STIM1 , 2011, Journal of leukocyte biology.

[36]  N. Demaurex,et al.  The role of calcium signaling in phagocytosis , 2010, Journal of leukocyte biology.

[37]  P. Cresswell,et al.  Defective Cross-Presentation of Viral Antigens in GILT-Free Mice , 2010, Science.

[38]  S. Maschalidi,et al.  Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells. , 2009, Immunity.

[39]  P. van Endert,et al.  IRAP Identifies an Endosomal Compartment Required for MHC Class I Cross-Presentation , 2009, Science.

[40]  N. Hacohen,et al.  The small GTPase Rac2 controls phagosomal alkalinization and antigen crosspresentation selectively in CD8(+) dendritic cells. , 2009, Immunity.

[41]  Katrin Schwarz,et al.  Nanoparticles target distinct dendritic cell populations according to their size , 2008, European journal of immunology.

[42]  E. Lamperti,et al.  Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance , 2008, Nature Immunology.

[43]  L. Otten,et al.  In vivo transformation of mouse conventional CD8alpha+ dendritic cells leads to progressive multisystem histiocytosis. , 2008, Blood.

[44]  K. Kabashima,et al.  CXCL12-CXCR4 engagement is required for migration of cutaneous dendritic cells. , 2007, The American journal of pathology.

[45]  K. Hirata,et al.  Efficient Cross-Presentation by Heat Shock Protein 90-Peptide Complex-Loaded Dendritic Cells via an Endosomal Pathway , 2007, The Journal of Immunology.

[46]  G. Raposo,et al.  Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes , 2007, Nature Cell Biology.

[47]  J. Buchanan,et al.  The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER–plasma membrane junctions , 2006, The Journal of cell biology.

[48]  G. Raposo,et al.  NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells , 2006, Cell.

[49]  K. Krause,et al.  Rapid Generation of Stable Transgenic Embryonic Stem Cell Lines Using Modular Lentivectors , 2006, Stem cells.

[50]  D. Accapezzato,et al.  Chloroquine enhances human CD8+ T cell responses against soluble antigens in vivo , 2005, The Journal of experimental medicine.

[51]  S. Grinstein,et al.  The nature of the phagosomal membrane: endoplasmic reticulum versus plasmalemma , 2005, Journal of leukocyte biology.

[52]  P. Cresswell,et al.  Cellular mechanisms governing cross-presentation of exogenous antigens , 2004, Nature Immunology.

[53]  B. Ludewig,et al.  CCL19/CCL21-triggered signal transduction and migration of dendritic cells requires prostaglandin E2. , 2004, Blood.

[54]  J. Davoust,et al.  ER–phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells , 2003, Nature.

[55]  Etienne Gagnon,et al.  Endoplasmic Reticulum-Mediated Phagocytosis Is a Mechanism of Entry into Macrophages , 2002, Cell.

[56]  S. Grinstein,et al.  Determinants of the Phagosomal pH in Neutrophils* , 2002, The Journal of Biological Chemistry.

[57]  P. Marrack,et al.  Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo. , 2001, Cellular immunology.

[58]  D. Clapham,et al.  Fundamental Ca2+ Signaling Mechanisms in Mouse Dendritic Cells: CRAC Is the Major Ca2+ Entry Pathway , 2001, The Journal of Immunology.

[59]  W. Reith,et al.  Conditional gene targeting in macrophages and granulocytes using LysMcre mice , 1999, Transgenic Research.

[60]  Kristin A. Hogquist,et al.  T cell receptor antagonist peptides induce positive selection , 1994, Cell.

[61]  G. Freeman,et al.  Cloning of Ly-5 cDNA. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[62]  Hong Zhang,et al.  PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS STIM 1 calcium sensor is required for activation of the phagocyte oxidase during in fl ammation and host defense , 2014 .

[63]  I. Nonaka,et al.  Dominant mutations in ORAI 1 cause tubular aggregate myopathy with hypocalcemia via constitutive activation of store-operated Ca 2 1 channels , 2014 .

[64]  P. Guermonprez,et al.  Measuring pH, ROS production, maturation, and degradation in dendritic cell phagosomes using cytofluorometry-based assays. , 2010, Methods in molecular biology.

[65]  T. Deerinck,et al.  NCMIR methods for 3D EM: a new protocol for preparation of biological specimens for serial block face scanning electron microscopy , 2010 .

[66]  D. Russell,et al.  Real-time spectrofluorometric assays for the lumenal environment of the maturing phagosome. , 2008, Methods in molecular biology.

[67]  R. Tampé,et al.  Access of soluble antigens to the endoplasmic reticulum can explain cross-presentation by dendritic cells , 2005, Nature Immunology.

[68]  D. Clapham,et al.  Fundamental Ca 2 1 Signaling Mechanisms in Mouse Dendritic Cells : CRAC Is the Major Ca 2 1 Entry Pathway , 2001 .

[69]  C. Harding,et al.  Pathways of antigen processing. , 1991, Current opinion in immunology.