APAF-1 signaling in human melanoma.
暂无分享,去创建一个
[1] M. D. Den Boer,et al. Decreased PARP and procaspase-2 protein levels are associated with cellular drug resistance in childhood acute lymphoblastic leukemia. , 2005, Blood.
[2] C. Belka,et al. Array-based comparative gene expression analysis of tumor cells with increased apoptosis resistance after hypoxic selection , 2005, Oncogene.
[3] Amato J Giaccia,et al. The role of p53 in hypoxia-induced apoptosis. , 2005, Biochemical and biophysical research communications.
[4] D. Green,et al. Apoptotic Pathways: Ten Minutes to Dead , 2005, Cell.
[5] O. Cuvillier,et al. Caspase-10 Triggers Bid Cleavage and Caspase Cascade Activation in FasL-induced Apoptosis* , 2005, Journal of Biological Chemistry.
[6] T. Mak,et al. Specific Ablation of the Apoptotic Functions of Cytochrome c Reveals a Differential Requirement for Cytochrome c and Apaf-1 in Apoptosis , 2005, Cell.
[7] S. Orrenius,et al. Plasma membrane sequestration of apoptotic protease-activating factor-1 in human B-lymphoma cells: a novel mechanism of chemoresistance. , 2005, Blood.
[8] W. Sadee,et al. ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma. , 2005, Cancer research.
[9] H. Pilch,et al. Expression of Apaf-1 in cervical cancer correlates with lymph node metastasis but not with intratumoral hypoxia. , 2005, Gynecologic oncology.
[10] R. Kim,et al. Recent advances in understanding the cell death pathways activated by anticancer therapy , 2005, Cancer.
[11] P. Clarke,et al. Protein Kinase A Regulates Caspase-9 Activation by Apaf-1 Downstream of Cytochrome c* , 2005, Journal of Biological Chemistry.
[12] Yigong Shi,et al. Structure of the apoptotic protease-activating factor 1 bound to ADP , 2005, Nature.
[13] M. Ueda,et al. Decreased expression of Apaf-1 with progression of melanoma. , 2005, Pigment cell research.
[14] D. Hoon,et al. Allelic imbalance of APAF-1 locus at 12q23 is related to progression of colorectal carcinoma , 2004, Oncogene.
[15] M. Daniotti,et al. Genetic progression of metastatic melanoma. , 2004, Cancer letters.
[16] David Loegering,et al. Components of the Cell Death Machine and Drug Sensitivity of the National Cancer Institute Cell Line Panel , 2004, Clinical Cancer Research.
[17] A. Anichini,et al. Apoptosis Protease Activator Protein-1 Expression Is Dispensable for Response of Human Melanoma Cells to Distinct Proapoptotic Agents , 2004, Cancer Research.
[18] T. Mak,et al. Nucling Recruits Apaf-1/Pro-caspase-9 Complex for the Induction of Stress-induced Apoptosis* , 2004, Journal of Biological Chemistry.
[19] T. Mak,et al. Induced Inhibition of Ischemic/Hypoxic Injury by APIP, a Novel Apaf-1-interacting Protein* , 2004, Journal of Biological Chemistry.
[20] G. Kroemer,et al. Nuclear Localization of Apoptosis Protease Activating Factor-1 Predicts Survival after Tumor Resection in Early-Stage Non–Small Cell Lung Cancer , 2004, Clinical Cancer Research.
[21] M. Martinka,et al. Reduced Apaf-1 expression in human cutaneous melanomas , 2004, British Journal of Cancer.
[22] M. Pierotti,et al. BRAF alterations are associated with complex mutational profiles in malignant melanoma , 2004, Oncogene.
[23] E. Borden,et al. Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis , 2004, Cell Death and Differentiation.
[24] Tak W. Mak,et al. Pathways of apoptotic and non-apoptotic death in tumour cells , 2004, Nature Reviews Cancer.
[25] D. Vaux,et al. Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die , 2004, The Journal of cell biology.
[26] D. Elashoff,et al. Allelic Imbalance on 12q22-23 in Serum Circulating DNA of Melanoma Patients Predicts Disease Outcome , 2004, Cancer Research.
[27] D. Elashoff,et al. Allelic Imbalance of 12q22–23 Associated with APAF-1 Locus Correlates with Poor Disease Outcome in Cutaneous Melanoma , 2004, Cancer Research.
[28] G. Botti,et al. Analysis of APAF‐1 expression in human cutaneous melanoma progression , 2004, Experimental dermatology.
[29] T. Mak,et al. Coupling of caspase‐9 to Apaf1 in response to loss of pRb or cytotoxic drugs is cell‐type‐specific , 2004, The EMBO journal.
[30] S. Korsmeyer,et al. Cell Death Critical Control Points , 2004, Cell.
[31] G. Shore,et al. Regulation of apoptosis by endoplasmic reticulum pathways , 2003, Oncogene.
[32] O. Tachibana,et al. Frequent LOH at Chromosome 12q22‐23 and Apaf‐1 Inactivation in Glioblastoma , 2003, Brain pathology.
[33] Gang Li,et al. Tissue-specific regulation of Apaf-1 expression by p53. , 2003, Oncology reports.
[34] M. Lanotte,et al. Apoptosome-independent Pathway for Apoptosis , 2003, Journal of Biological Chemistry.
[35] L. Chin. The genetics of malignant melanoma: lessons from mouse and man , 2003, Nature Reviews Cancer.
[36] Z. Ronai,et al. Death receptors and melanoma resistance to apoptosis , 2003, Oncogene.
[37] F. Haluska,et al. PTEN signaling pathways in melanoma , 2003, Oncogene.
[38] S. Lowe,et al. Apoptosis and melanoma chemoresistance , 2003, Oncogene.
[39] P. Hersey,et al. Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria , 2003, Oncogene.
[40] L. Frati,et al. Survivin, bcl-2, bax, and bcl-X gene expression in sentinel lymph nodes from melanoma patients. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[41] N. Chandel,et al. Oxygen deprivation induced cell death: An update , 2002, Apoptosis.
[42] Keisuke Kuida,et al. Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome , 2002, Nature.
[43] Ximena Opitz-Araya,et al. Requirement for Caspase-2 in Stress-Induced Apoptosis Before Mitochondrial Permeabilization , 2002, Science.
[44] C. Sawyers,et al. The phosphatidylinositol 3-Kinase–AKT pathway in human cancer , 2002, Nature Reviews Cancer.
[45] P. Krammer,et al. Tumor Immunology , 2018, Medical Immunology.
[46] Xuejun Jiang,et al. Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. , 2002, Molecular cell.
[47] Yuri Lazebnik,et al. Identification of Omi/HtrA2 as a Mitochondrial Apoptotic Serine Protease That Disrupts Inhibitor of Apoptosis Protein-Caspase Interaction* , 2002, The Journal of Biological Chemistry.
[48] P. Hersey,et al. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria. , 2001, Cancer research.
[49] C. Harris,et al. APAF-1 is a transcriptional target of p53 in DNA damage-induced apoptosis. , 2001, Cancer research.
[50] R. Larsson,et al. Characteristics of etoposide-induced apoptotic cell death in the U-937 human lymphoma cell line , 2001, Anti-cancer drugs.
[51] N Cascinelli,et al. Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[52] Martin F. Mihm,et al. Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[53] S. Srinivasula,et al. Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells. , 2001, Blood.
[54] A. Asai,et al. Co‐transduction of Apaf‐1 and Caspase‐9 Augments Etoposide‐induced Apoptosis in U‐373MG Glioma Cells , 2001, Japanese journal of cancer research : Gann.
[55] A. Godzik,et al. A Novel Enhancer of the Apaf1 Apoptosome Involved in Cytochrome c-dependent Caspase Activation and Apoptosis* , 2001, The Journal of Biological Chemistry.
[56] A. Newland,et al. Apaf-1XL is an inactive isoform compared with Apaf-1L. , 2001, Biochemical and biophysical research communications.
[57] G. Kroemer,et al. Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis , 2001, Oncogene.
[58] S. B. Bratton,et al. Recruitment, activation and retention of caspases‐9 and ‐3 by Apaf‐1 apoptosome and associated XIAP complexes , 2001, The EMBO journal.
[59] D. Vaux,et al. Diablo Promotes Apoptosis by Removing Miha/Xiap from Processed Caspase 9 , 2001, The Journal of cell biology.
[60] W. Gerald,et al. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma , 2001, Nature.
[61] G. Salvesen,et al. ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas , 2000, Current Biology.
[62] Guido Kroemer,et al. Hsp27 negatively regulates cell death by interacting with cytochrome c , 2000, Nature Cell Biology.
[63] S. Srinivasula,et al. Negative regulation of cytochrome c‐mediated oligomerization of Apaf‐1 and activation of procaspase‐9 by heat shock protein 90 , 2000, The EMBO journal.
[64] Emad S. Alnemri,et al. Negative regulation of the Apaf-1 apoptosome by Hsp70 , 2000, Nature Cell Biology.
[65] Dick D. Mosser,et al. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome , 2000, Nature Cell Biology.
[66] Xiaodong Wang,et al. Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition , 2000, Cell.
[67] G. Núñez,et al. Expression and Functional Analysis of Apaf-1 Isoforms , 2000, The Journal of Biological Chemistry.
[68] Junying Yuan,et al. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β , 2000, Nature.
[69] H. Stein,et al. Three new types of Apaf-1 in mammalian cells. , 1999, Biochemical and biophysical research communications.
[70] Seamus J. Martin,et al. Regulation of Apoptotic Protease Activating Factor-1 Oligomerization and Apoptosis by the WD-40 Repeat Region* , 1999, The Journal of Biological Chemistry.
[71] P. Hersey,et al. Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma. , 1999, Cancer research.
[72] X. Liu,et al. An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9* , 1999, The Journal of Biological Chemistry.
[73] S. Lowe,et al. Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. , 1999, Science.
[74] Francesco Cecconi,et al. Apaf1 (CED-4 Homolog) Regulates Programmed Cell Death in Mammalian Development , 1998, Cell.
[75] T. Mak,et al. Apaf1 Is Required for Mitochondrial Pathways of Apoptosis and Brain Development , 1998, Cell.
[76] S. Srinivasula,et al. Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. , 1998, Molecular cell.
[77] S. Srinivasula,et al. Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade , 1997, Cell.
[78] Xiaodong Wang,et al. Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3 , 1997, Cell.
[79] Margot Thome,et al. Inhibition of death receptor signals by cellular FLIP , 1997, Nature.
[80] P. Galle,et al. Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53. , 1997, The Journal of clinical investigation.
[81] M. Hengartner,et al. Caenorhabditis elegans gene ced-9 protects cells from programmed cell death , 1992, Nature.
[82] H. Horvitz,et al. The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death. , 1990, Developmental biology.
[83] R. Seale. Studies on the mode of segregation of histone nu bodies during replication in HeLa cells , 1976, Cell.
[84] L. Altucci,et al. ERRATUM: Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway , 2005, Nature Medicine.
[85] Lucia Altucci,et al. Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway , 2005, Nature Medicine.