Inhibition of the NF-κB transcription factor increases Bax expression in cancer cell lines

[1]  Renaud Mahieux,et al.  Inactivation of p53 by Human T-Cell Lymphotropic Virus Type 1 Tax Requires Activation of the NF-κB Pathway and Is Dependent on p53 Phosphorylation , 2000, Molecular and Cellular Biology.

[2]  M. Oren.  Regulation of the p53 Tumor Suppressor Protein* , 1999, The Journal of Biological Chemistry.

[3]  Xianglin Shi,et al.  Involvement of 5′-Flanking κB-like Sites withinbcl-x Gene in Silica-induced Bcl-x Expression* , 1999, The Journal of Biological Chemistry.

[4]  M. Kannagi,et al.  Induction of Bcl-xL Expression by Human T-Cell Leukemia Virus Type 1 Tax through NF-κB in Apoptosis-Resistant T-Cell Transfectants with Tax , 1999, Journal of Virology.

[5]  C. Glass,et al.  Transcriptional Activation by NF-κB Requires Multiple Coactivators , 1999, Molecular and Cellular Biology.

[6]  S. Korsmeyer,et al.  The activity of the murine Bax promoter is regulated by Sp1/3 and E-box binding proteins but not by p53 , 1999, Cell Death and Differentiation.

[7]  G. Cheng,et al.  NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[8]  N. Perkins,et al.  Transcriptional Cross Talk between NF-κB and p53 , 1999, Molecular and Cellular Biology.

[9]  A. Jochemsen,et al.  Distinct Regulation of p53 and p73 Activity by Adenovirus E1A, E1B, and E4orf6 Proteins , 1999, Molecular and Cellular Biology.

[10]  M. Merville,et al.  Regulation of NF-κB activity by IκB-related proteins in adenocarcinoma cells , 1999, Oncogene.

[11]  J. Cusack,et al.  Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB , 1999, Nature Medicine.

[12]  Haruo Okado,et al.  Tumor Necrosis Factor Induces Bcl-2 and Bcl-x Expression through NFκB Activation in Primary Hippocampal Neurons* , 1999, The Journal of Biological Chemistry.

[13]  M. Merville,et al.  IκB-α Enhances Transactivation by the HOXB7 Homeodomain-containing Protein* , 1999, The Journal of Biological Chemistry.

[14]  M. Merville,et al.  Stable inhibition of nuclear factor kappaB in cancer cells does not increase sensitivity to cytotoxic drugs. , 1999, Cancer research.

[15]  W. Zong,et al.  The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis , 1999 .

[16]  R. Wadgaonkar,et al.  CREB-binding Protein Is a Nuclear Integrator of Nuclear Factor-κB and p53 Signaling* , 1999, The Journal of Biological Chemistry.

[17]  John C Reed,et al.  Bcl-2 family proteins , 1998, Oncogene.

[18]  W. El-Deiry,et al.  p53-mediated repression of nuclear factor-kappaB RelA via the transcriptional integrator p300. , 1998, Cancer research.

[19]  C. Y. Wang,et al.  NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. , 1998, Science.

[20]  H. Friess,et al.  bax, but notbcl-2, influences the prognosis of human pancreatic cancer , 1998, Gut.

[21]  S. Cory,et al.  The Bcl-2 protein family: arbiters of cell survival. , 1998, Science.

[22]  S. Cannistra,et al.  BAX protein expression and clinical outcome in epithelial ovarian cancer. , 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[23]  Christian Stehlik,et al.  Nuclear Factor (NF)-κB–regulated X-chromosome–linked iap Gene Expression Protects Endothelial Cells from Tumor Necrosis Factor α–induced Apoptosis , 1998, The Journal of experimental medicine.

[24]  John Calvin Reed.  Dysregulation of apoptosis in cancer. , 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[25]  Hueng-Sik Choi,et al.  Steroid Receptor Coactivator-1 Interacts with the p50 Subunit and Coactivates Nuclear Factor κB-mediated Transactivations* , 1998, The Journal of Biological Chemistry.

[26]  Hui Tian,et al.  BRCA1 physically associates with p53 and stimulates its transcriptional activity , 1998, Oncogene.

[27]  Philippe Calmant,et al.  Nuclear factor – κB-dependent regulation of p53 gene expression induced by daunomycin genotoxic drug , 1998, Oncogene.

[28]  C. Prives,et al.  High mobility group protein-1 (HMG-1) is a unique activator of p53. , 1998, Genes & development.

[29]  N. Tarantino,et al.  Discrimination between RelA and RelB Transcriptional Regulation by a Dominant Negative Mutant of IκBα* , 1998, The Journal of Biological Chemistry.

[30]  B. Dörken,et al.  Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells. , 1997, The Journal of clinical investigation.

[31]  A. E. Rogers,et al.  Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer. , 1997, The Journal of clinical investigation.

[32]  J. Boss,et al.  Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB , 1997, Molecular and cellular biology.

[33]  K. Gardner,et al.  Recruitment of p300/CBP in p53-Dependent Signal Pathways , 1997, Cell.

[34]  Wei Gu,et al.  Synergistic activation of transcription by CBP and p53 , 1997, Nature.

[35]  C. White,et al.  Activation of NF-kappaB by antineoplastic agents. Role of protein kinase C. , 1997, The Journal of biological chemistry.

[36]  M. Gerritsen,et al.  CREB-binding protein/p300 are transcriptional coactivators of p65. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[37]  J C Reed,et al.  Somatic Frameshift Mutations in the BAX Gene in Colon Cancers of the Microsatellite Mutator Phenotype , 1997, Science.

[38]  G. Nabel,et al.  Regulation of NF-κB by Cyclin-Dependent Kinases Associated with the p300 Coactivator , 1997, Science.

[39]  N. Tarantino,et al.  IκBα Overexpression in Human Breast Carcinoma MCF7 Cells Inhibits Nuclear Factor-κB Activation but Not Tumor Necrosis Factor-α-induced Apoptosis* , 1997, The Journal of Biological Chemistry.

[40]  J. Piette,et al.  Interleukin-1 beta induces nuclear factor kappa B in epithelial cells independently of the production of reactive oxygen intermediates. , 1996, European journal of biochemistry.

[41]  David Baltimore,et al.  An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death , 1996, Science.

[42]  Marty W. Mayo,et al.  TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB , 1996, Science.

[43]  J. Piette,et al.  Topoisomerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells. , 1996, Nucleic acids research.

[44]  D. Katz,et al.  Inhibition of NF‐kappaB/Rel induces apoptosis of murine B cells. , 1996, The EMBO journal.

[45]  G. Farmer,et al.  Functional interaction between p53, the TATA-binding protein (TBP), andTBP-associated factors in vivo , 1996, Molecular and Cellular Biology.

[46]  S. Vogel,et al.  Paclitaxel (Taxol)-induced NF-kappaB translocation in murine macrophages , 1996, Infection and immunity.

[47]  A. Israël,et al.  N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity , 1995, Molecular and cellular biology.

[48]  M. Meisterernst,et al.  Interaction of the COOH-terminal Transactivation Domain of p65 NF-κB with TATA-binding Protein, Transcription Factor IIB, and Coactivators (*) , 1995, The Journal of Biological Chemistry.

[49]  S. Gerstberger,et al.  Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation , 1995, Science.

[50]  John Calvin Reed,et al.  Tumor suppressor p53 is a direct transcriptional activator of the human bax gene , 1995, Cell.

[51]  Dimitris Thanos,et al.  The High Mobility Group protein HMG I(Y) is required for NF-κB-dependent virus induction of the human IFN-β gene , 1992, Cell.

[52]  V. Bours,et al.  A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site , 1992, Molecular and cellular biology.

[53]  R. Weichselbaum,et al.  Ionizing radiation induces expression and binding activity of the nuclear factor kappa B. , 1991, The Journal of clinical investigation.

[54]  Y. Tsujimoto,et al.  Involvement of the bcl-2 gene in human follicular lymphoma. , 1985, Science.

[55]  D. Chao,et al.  BCL-2 family: regulators of cell death. , 1998, Annual review of immunology.

[56]  A. Baldwin,et al.  THE NF-κB AND IκB PROTEINS: New Discoveries and Insights , 1996 .

[57]  G. Franzoso,et al.  Structure, regulation and function of NF-kappa B. , 1994, Annual review of cell biology.