Mathematic modeling of the risk of HBV, HCV, and HIV transmission by window‐phase donations not detected by NAT

BACKGROUND: Blood transfusion centers around the world have introduced minipool NAT to reduce the risk of HBV, HCV, and HIV transmission by blood donations drawn in the infectious window phase. What would be the reduction in the residual risk when minipool NAT would be replaced by single‐donation NAT?

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