Schizophrenia after Prenatal Exposure to 1957 A2 Influenza Epidemic

“The birth dates of schizophrenic inpatients in eight health regions in England and Wales were reviewed for any effect of the 1957 A2 influenza epidemic. 5 months after the peak infection prevalence, the number of births of individuals who later developed schizophrenia was 88% higher than the average number of such births in the corresponding periods of the 2 previous and the next 2 years. This finding is in accordance with a study from Helsinki and with clinical and neuropathological evidence of aberrant fetal brain development in the pathogenesis of schizophrenia.”

[1]  R. Murray,et al.  Schizophrenia after prenatal exposure to 1957 A2 influenza epidemic , 1991, The Lancet.

[2]  E. Torrey,et al.  Influenza and schizophrenia: Helsinki vs Edinburgh. , 1990, Archives of general psychiatry.

[3]  S. Mednick,et al.  Exposure to influenza epidemics during gestation and adult schizophrenia. A 40-year study. , 1990, Archives of general psychiatry.

[4]  R. Kendell,et al.  Maternal influenza in the etiology of schizophrenia. , 1989, Archives of general psychiatry.

[5]  M. Swash,et al.  No viral antigens detected in brain tissue from a case of acute encephalitis lethargica and another case of post-encephalitic parkinsonism. , 1989, Journal of neurology, neurosurgery, and psychiatry.

[6]  M J Mayaux,et al.  Seasonal distribution in conceptions achieved by artificial insemination by donor , 1989, BMJ.

[7]  D. King,et al.  Viruses, Immunity and Mental Disorder , 1989, British Journal of Psychiatry.

[8]  G. Pennington,et al.  Seasonal distribution in conceptions achieved by artificial insemination by donor. , 1988, BMJ.

[9]  D. Bonett,et al.  Adult schizophrenia following prenatal exposure to an influenza epidemic. , 1988, Archives of general psychiatry.

[10]  S. Cooper,et al.  A Survey of Serum Antibodies to Eight Common Viruses in Psychiatric Patients , 1985, British Journal of Psychiatry.

[11]  I. Jones,et al.  Seasonal births in schizophrenia , 1979, Acta psychiatrica Scandinavica.

[12]  G. Parker,et al.  Mental Disorder and Season of Birth—A Southern Hemisphere Study , 1976, British Journal of Psychiatry.