Neurohumoral mechanism of space motion sickness.

This paper reviews existing hypotheses concerning the mechanisms of adaptation of the vestibular apparatus and related somatosensory systems to microgravity with reference to the flight data. Having in view theoretical concepts and experimental data accumulated in space flights, a conceptual model of the development of a funtional system responsible for the termination of vestibular dysfuntion and space motion sickness manifestations is presented. It is also shown that changes in the hormonal status during motion sickness induced by vestibular stimulation give evidence that endocrine regulation of certain functions can be involved in adaptive responses.

[1]  R. Klinke,et al.  Efferent innervation of vestibular and auditory receptors. , 1974, Physiological reviews.

[2]  W. Precht.  Physiological Aspects of the Efferent Vestibular System , 1974 .

[3]  Hillman Bj.  Digital radiologic monitoring of renal physiology. , 1983 .

[4]  K. Hagbarth,et al.  Central influences on spinal afferent conduction. , 1954, Journal of neurophysiology.

[5]  G. I. Samarin,et al.  [Interlabyrinthine asymmetry, vestibular dysfunction and space motion sickness]. , 1986, Kosmicheskaia biologiia i aviakosmicheskaia meditsina.

[6]  R. Gacek.  Morphological Aspects of the Efferent Vestibular System , 1974 .

[7]  P Howard.  Man in Weightlessness. , 1969, Journal of the Royal College of Physicians of London.