Discharge properties of group III and IV muscle afferents.

Stimulation of group III and IV muscle afferents has been shown to have important reflex effects on both the somatic and autonomic nervous systems. These include an inhibitory effect on alpha motoneurones, an excitatory effect on gamma motoneurones and an excitatory effect on the sympathetic nervous system. The purpose of this review is to describe the mechanical and metabolic stimuli that discharge group III and IV muscle afferents. Particular attention will be paid to the responses of these afferents to dynamic exercise induced by electrical stimulation of the mesencephalic locomotor region.

[1]  Douglas G. Stuart,et al.  Ensemble characterivstics ofcat locovmotionand its neural control , 1976, Progress in Neurobiology.

[2]  J. Hill,et al.  Dynamic exercise stimulates group III muscle afferents. , 1994, Journal of neurophysiology.

[3]  Michael J. O'Donovan,et al.  Cat hindlimb motoneurons during locomotion. II. Normal activity patterns. , 1987, Journal of neurophysiology.

[4]  F E Zajac,et al.  Relationship among recruitment order, axonal conduction velocity, and muscle-unit properties of type-identified motor units in cat plantaris muscle. , 1985, Journal of neurophysiology.

[5]  M. Kaufman,et al.  Discharge Properties of Group III and IV Muscle Afferents: Their Responses to Mechanical and Metabolic Stimuli , 1987, Circulation research.

[6]  M. Kaufman,et al.  Gadolinium attenuates exercise pressor reflex in cats. , 2001, American journal of physiology. Heart and circulatory physiology.

[7]  G. Somjen,et al.  FUNCTIONAL SIGNIFICANCE OF CELL SIZE IN SPINAL MOTONEURONS. , 1965, Journal of neurophysiology.

[8]  Phototransformation of porphyrins in frozen solutions. Oxidative medium , 1968 .

[9]  Ksenija Jovanovic´,et al.  Reflex effects on γ fusimotor neurones of chemically induced discharges in small-diameter muscle afferents in decerebrate cats , 1990, Brain Research.

[10]  T. Kumazawa,et al.  Thin‐fibre receptors responding to mechanical, chemical, and thermal stimulation in the skeletal muscle of the dog , 1977, The Journal of physiology.

[11]  J. Mitchell,et al.  Effects of static muscular contraction on impulse activity of groups III and IV afferents in cats. , 1983, Journal of applied physiology: respiratory, environmental and exercise physiology.

[12]  W. Rymer,et al.  Effects of muscle fatigue on mechanically sensitive afferents of slow conduction velocity in the cat triceps surae. , 1991, Journal of neurophysiology.

[13]  L. Sinoway,et al.  Effects of contraction and lactic acid on the discharge of group III muscle afferents in cats. , 1993, Journal of neurophysiology.

[14]  F. Thimm,et al.  Response of chemosensitive nerve fibers of group III and IV to metabolic changes in rat muscles , 1987, Pflügers Archiv.

[15]  T. Waldrop,et al.  Increasing gracilis muscle interstitial potassium concentrations stimulate group III and IV afferents. , 1985, Journal of applied physiology.

[16]  J. Hill,et al.  Cyclooxygenase blockade attenuates responses of group IV muscle afferents to static contraction. , 1990, The American journal of physiology.

[17]  C. Adreani,et al.  Effect of arterial occlusion on responses of group III and IV afferents to dynamic exercise. , 1998, Journal of applied physiology.

[18]  R F Schmidt,et al.  Activation of group IV afferent units from muscle by algesic agents. , 1974, Brain research.

[19]  S. Mense.  Sensitization of group IV muscle receptors to bradykinin by 5-hydroxytryptamine and prostaglandin E2 , 1981, Brain Research.

[20]  J. Orr,et al.  Stimulation of group III and IV afferent nerves from the hindlimb by thromboxane A2 , 1997, Brain Research.

[21]  S. Mense.  Nervous outflow from skeletal muscle following chemical noxious stimulation , 1977, The Journal of physiology.

[22]  C. Adreani,et al.  Responses of group III and IV muscle afferents to dynamic exercise. , 1997, Journal of applied physiology.

[23]  Michael J. O'Donovan,et al.  Cat hindlimb motoneurons during locomotion. I. Destination, axonal conduction velocity, and recruitment threshold. , 1987, Journal of neurophysiology.

[24]  J. Longhurst,et al.  Sensitization of group III muscle afferents to static contraction by arachidonic acid. , 1990, Journal of applied physiology.

[25]  C. Roussos,et al.  The effects of ischemia, lactic acid and hypertonic sodium chloride on phrenic afferent discharge during spontaneous diaphragmatic contraction , 1986, Neuroscience Letters.

[26]  T. Waldrop,et al.  Effect of ischemia on responses of group III and IV afferents to contraction. , 1984, Journal of applied physiology: respiratory, environmental and exercise physiology.

[27]  E. Bockman.  Blood flow and oxygen consumption in active soleus and gracilis muscles in cats. , 1983, American Journal of Physiology.

[28]  P. Hník,et al.  Activatioof muscle afferents by nonproprioceptive stimuli. , 1969, The American journal of physiology.

[29]  A. Paintal,et al.  Functional analysis of Group III afferent fibres of mammalian muscles , 1960, The Journal of physiology.

[30]  P H Ellaway,et al.  Closely coupled excitation of γ‐motoneurones by group III muscle afferents with low mechanical threshold in the cat , 1982, The Journal of physiology.

[31]  M. C. Palazzotto,et al.  Photophysics of a Zn(Cd)S phosphor on an extended time scale , 1985 .

[32]  J. Coast.  Handbook of Physiology. Section 12. Exercise: Regulation and Integration of Multiple Systems , 1997 .

[33]  S. Mense,et al.  Responses in muscle afferent fibres of slow conduction velocity to contractions and ischaemia in the cat. , 1983, The Journal of physiology.

[34]  Organization and sensory properties of small myelinated fibres in the dorsal cervical rami of the cat. , 1984, The Journal of physiology.

[35]  R. Schmidt,et al.  Responses of group IV afferent units from skeletal muscle to stretch, contraction and chemical stimulation , 1978, Experimental Brain Research.

[36]  M. Kaufman,et al.  Effect of metabolic products of muscular contraction on discharge of group III and IV afferents. , 1988, Journal of applied physiology.

[37]  Michael J. O'Donovan,et al.  Discharge patterns of hindlimb motoneurons during normal cat locomotion. , 1981, Science.

[38]  S. Mense,et al.  Bradykinin‐induced modulation of the response behaviour of different types of feline group III and IV muscle receptors. , 1988, The Journal of physiology.

[39]  W. Z. Rymer,et al.  Increased inhibitory effects on close synergists during muscle fatigue in the decerebrate cat , 1988, Brain Research.

[40]  J. Mitchell,et al.  Effects of static and rhythmic twitch contractions on the discharge of group III and IV muscle afferents. , 1984, Cardiovascular research.