GC MS AND ELEMENTAL ANALYSIS OF CINNAMOMUM TAMALA

Objective: To investigate the phytoconstituents and elements present in hexane (HEX), dichloromethane (DCM) and methanol (MET) extracts of Cinnamomum tamala ( CT ). Methods: Gas chromatography–mass spectrometry (GC-MS) was carried out to determine the principal constituents present in HEX, DCM and MET extracts of CT . Elemental analysis of CT was carried out by X–Ray Fluorescence (XRF) spectrophotometer analysis. Results: GC-MS analysis showed the presence of various compounds in HEX, DCM and MET extracts of CT . Eugenol was found to be the major compound in HEX and DCM extracts of CT . 2 compounds namely 2,6,10-trimethyl-12-oxatricyclo[7.3.0.0{1,6}]tridec-2-ene, Hexahydropyridine,4-[4,5-dimethoxyphenyl]-in HEX extract and 3 compounds in DCM extract namely 6a,19-CycloAndrost-4-ene-3,17-dione, 2,5-chloro-3β-hydroxy-6β-nitro-5α-androstan-17-one, Aceticacid,10,13-dimethyl-2-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H cyclopenta [a]phenanthren-17-ylester are newly reported. XRF analysis revealed the presence of various elements in CT . Out of these; calcium and potassium were found to be major elements, whereas titanium was found to be a minor element. Conclusions: The results of the present study demonstrate the presence of 31 various important phytoconstituents in HEX, DCM and MET extracts of CT and presence of 13 elements in CT .

[1]  M. Hassouni,et al.  Antioxidant activities and total phenol content of Inula viscosa extracts selected from three regions of Morocco. , 2015 .

[2]  Kaixian Chen,et al.  Immunosuppressive Effects of A-Type Procyanidin Oligomers from Cinnamomum tamala , 2014, Evidence-based complementary and alternative medicine : eCAM.

[3]  Md. Abul Hasnat,et al.  In vitro antioxidant and anti–inflammatory activities of Korean blueberry (Vaccinium corymbosum L.) extracts , 2014 .

[4]  A. Phaniendra,et al.  Free Radicals: Properties, Sources, Targets, and Their Implication in Various Diseases , 2014, Indian Journal of Clinical Biochemistry.

[5]  A. Alam,et al.  Antioxidant potential of Rumex vesicarius L.: in vitro approach. , 2014, Asian Pacific journal of tropical biomedicine.

[6]  Vasundhara Sharma,et al.  An Overview on Chemical Composition, Bioactivity and Processing of Leaves of Cinnamomum tamala , 2014, Critical reviews in food science and nutrition.

[7]  A. Kundu,et al.  Simultaneous HPLC Determination of 22 Components of Essential Oils; Method Robustness with Experimental Design , 2014, Indian journal of pharmaceutical sciences.

[8]  A. Pandey,et al.  Antifungal and antioxidative potential of oil and extracts derived from leaves of Indian spice plant Cinnamomum tamala. , 2012, Cellular and molecular biology.

[9]  S. Sisodia,et al.  Assessment of antidiabetic potential of Cinnamomum tamala leaves extract in streptozotocin induced diabetic rats , 2011, Indian journal of pharmacology.

[10]  M. Vijayakumar,et al.  Gastroprotective activity of Cinnamomum tamala leaves on experimental gastric ulcers in rats. , 2010, Journal of ethnopharmacology.

[11]  U. Chakraborty Antidiabetic and Antioxidant Activities of Cinnamomum tamala Leaf Extracts in Stz-Treated Diabetic Rats , 2010 .

[12]  Gurdip Singh,et al.  Chemistry, antimicrobial and antioxidant potentials of Cinnamomum tamala Nees & Eberm. (Tejpat) essential oil and oleoresins † , 2009 .

[13]  P. Kaushik,et al.  Laboratory Evaluation of Crude Extracts of Cinnamomum tamala for Potential Antibacterial Activity , 2009 .

[14]  M. Vijayakumar,et al.  Antidiarrhoeal activity of the standardised extract of Cinnamomum tamala in experimental rats , 2008, Journal of Natural Medicines.

[15]  S. Kannappan,et al.  Evaluation of in vitro antioxidant activity of Indian bay leaf, Cinnamomum tamala (Buch. -Ham.) T. Nees & Eberm using rat brain synaptosomes as model system. , 2007, Indian journal of experimental biology.

[16]  R. Sane,et al.  Quantification of Eugenol in Cinnamomum tamala Nees and Eberm. Leaf Powder by High-Performance Thin-Layer Chromatography , 2005, JPC – Journal of Planar Chromatography – Modern TLC.

[17]  M. Choudhary,et al.  Essential oil constituents of the spice Cinnamomum tamala (Ham.) Nees & Eberm. , 2000 .