论文信息 - Composite-microlens-array-enabled microfluidic sorting

Composite-microlens-array-enabled microfluidic sorting

We propose a simple, reliable and cost-effective method for microfluidic sorting of microparticles using an optical potential landscape projected by a composite microlens array (MLA). The MLA enables a high power efficient approach to forming composite shape and size of the projected pattern. Sorting particles by size is demonstrated both theoretically and experimentally.

[1] Ivan R. Perch-Nielsen,et al. Sorting particles in a microfluidic system using SLM-reconfigurable intensity patterns , 2006, SPIE BiOS.

[2] Ming C. Wu,et al. Massively parallel manipulation of single cells and microparticles using optical images , 2005, Nature.

[3] J. Sturm,et al. Continuous Particle Separation Through Deterministic Lateral Displacement , 2004, Science.

[4] Sean J. Hart,et al. Refractive-index-driven separation of colloidal polymer particles using optical chromatography , 2003 .

[5] S S Chan,et al. Sorting by diffusion: an asymmetric obstacle course for continuous molecular separation. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[6] A. Oudenaarden,et al. Brownian ratchets: molecular separations in lipid bilayers supported on patterned arrays. , 1999, Science.

[7] D. Grier,et al. Sorting mesoscopic objects with periodic potential landscapes: optical fractionation. , 2004, Physical review. E, Statistical, nonlinear, and soft matter physics.

[8] K. Dholakia,et al. Microfluidic sorting in an optical lattice , 2003, Nature.

[9] P. T. Korda,et al. Kinetically locked-in colloidal transport in an array of optical tweezers. , 2002, Physical review letters.

[10] Jesper Glückstad,et al. Dynamically reconfigurable optical lattices. , 2005, Optics express.

[11] S. Quake,et al. A microfabricated fluorescence-activated cell sorter , 1999, Nature Biotechnology.