Effect of hepatitis C virus core shadow protein expressed in human hepatoma cell line on human gene expression profiles

Background and Aims:  The hepatitis C virus (HCV) C region has been reported to have overlapping genes or regions, and may encode a core shadow protein that has a role in HCV self‐replication, pathogenesis and carcinogenesis. The aim of this study was to identify the effect of HCV core shadow protein expressed in a human hepatoma (Huh‐7) cell line on human gene expression profiles.

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