YY1 (Yin‐Yang 1), a transcription factor regulating systemic inflammation, is involved in cognitive impairment of depression

Clinical and preclinical studies suggest that alterations in the peripheral and brain immune system are associated with the pathophysiology of depression, also leading to changes in local glucose metabolism in the brain. Here, the authors identified Yin‐Yang 1 (YY1), a transcription factor closely associated with central and peripheral inflammation.

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