An immunohistochemical characterization of somatostatin‐28 and somatostatin‐281–12 in monkey prefrontal cortex

The distribution of the prosomatostatin‐derived peptides (PSDP) somatostatin‐28 (SS‐28) and somatostatin‐281–12 (SS‐281–12) was characterized immunohistochemically in the prefrontal cortical regions of both Old World cynomolgus monkeys (Macaca fascicularis) and New Worldsquirrel monkeys (Saimiri sciureus). Comparison of staining with antisera specific for each peptide revealed that these antigens were segregated within immunoreactive neurons such that SS‐28 was largely confined to theperinuclear region of the cell body whereas SS‐281–12 was primarily found in axons and dendrites.

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