Hounsfield Unit inaccuracy in computed tomography lesion size and density, diagnostic quality vs attenuation correction

In computed tomography the Hounsfield Units (HU) are used as an indicator of the tissue type based on the linear attenuation coefficients of the tissue. HU accuracy is essential when this metric is used in any form to support diagnosis. In hybrid imaging, such as SPECT/CT and PET/CT, the information is used for attenuation correction (AC) of the emission images. This work investigates the HU accuracy of nodules of known size and HU, comparing diagnostic quality (DQ) images with images used for AC.

[1]  Paras Shah,et al.  Using Hounsfield unit measurement and urine parameters to predict uric acid stones. , 2013, Urology.

[2]  T. Turkington,et al.  SPECT/CT Physical Principles and Attenuation Correction* , 2008, Journal of Nuclear Medicine Technology.

[3]  R. Kronmal,et al.  Measuring coronary calcium on CT images adjusted for attenuation differences. , 2005, Radiology.

[4]  J. Boone,et al.  Comprar Essential Physics Of Medical Imaging, International Edition | Jerrold T. Bushberg | 9781451118100 | Lippincott Williams & Wilkins , 2012 .

[5]  Andrew J. Krainik,et al.  Age and gender distributions of coronary artery calcium detected by electron beam tomography in 35,246 adults. , 2001, The American journal of cardiology.

[6]  J. Boone,et al.  CT Hounsfield numbers of soft tissues on unenhanced abdominal CT scans: variability between two different manufacturers' MDCT scanners. , 2014, AJR. American journal of roentgenology.

[7]  E. Kang,et al.  Hounsfield units upon PET/CT are useful in evaluating metastatic regional lymph nodes in patients with oesophageal squamous cell carcinoma. , 2012, The British journal of radiology.

[8]  D. Tso,et al.  Scanner and kVp dependence of measured CT numbers in the ACR CT phantom , 2013, Journal of applied clinical medical physics.

[10]  William R. Hendee The Essential Physics of Medical Imaging , 1994 .

[11]  Josef Hammer,et al.  The Use of F-18 Choline PET in the Assessment of Bone Metastases in Prostate Cancer: Correlation with Morphological Changes on CT , 2010, Molecular Imaging and Biology.

[12]  E Graif,et al.  CT number variations due to different image acquisition and reconstruction parameters: a thorax phantom study. , 2000, Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society.

[13]  M. Blake,et al.  Adrenal lesions: attenuation measurement differences between CT scanners. , 2006, Radiology.

[14]  James S Babb,et al.  Multi-detector row CT attenuation measurements: assessment of intra- and interscanner variability with an anthropomorphic body CT phantom. , 2007, Radiology.

[15]  Nasrollah Jabbari,et al.  Energy Dependence of Measured CT Numbers on Substituted Materials Used for CT Number Calibration of Radiotherapy Treatment Planning Systems , 2016, PloS one.

[16]  Hiroshi Okumura,et al.  Computed tomography Hounsfield units can predict breast cancer metastasis to axillary lymph nodes , 2014, BMC Cancer.

[17]  Adnan Gücük,et al.  Usefulness of hounsfield unit and density in the assessment and treatment of urinary stones. , 2014, World journal of nephrology.

[18]  K. Bailey,et al.  An algorithm for noninvasive identification of angiographic three-vessel and/or left main coronary artery disease in symptomatic patients on the basis of cardiac risk and electron-beam computed tomographic calcium scores. , 1999, Journal of the American College of Cardiology.