An evaluative report and challenges for fermentative biohydrogen production

Abstract Hydrogen, the most abundant and lightest element in the universe, has enormous potential as a future energy. High conversion efficiency, recyclability and nonpolluting nature of hydrogen make it the fuel of future. Various microorganisms are explored for producing hydrogen by exploiting variety of biological organic substrates. The target is the genetic improvement of the organism or the biochemical pathway required for biohydrogen production and devising path even better in comparison to the other production methods. The present review discusses different methods of biohydrogen production specifically by the fermentative route, physical factors affecting its production and other aspects for enhancement in the yield of hydrogen production. Metabolic engineering strategies for enhancement in hydrogen production to overcome different limitation have been also summarized.

[1]  Eleftherios T. Papoutsakis,et al.  Antisense RNA Strategies for Metabolic Engineering of Clostridium acetobutylicum , 1999, Applied and Environmental Microbiology.

[2]  Debabrata Das,et al.  Enhancement of hydrogen production by Enterobacter cloacae IIT-BT 08. , 2000 .

[3]  Bryan Olin.  Design of experiments in quality engineering , 1997 .

[4]  Thomas K. Wood,et al.  Metabolic engineering to enhance bacterial hydrogen production , 2007, Microbial biotechnology.

[5]  D. Block,et al.  Efficiency and cost goals for photoenhanced hydrogen production processes , 1992 .

[6]  B. Palsson,et al.  Combining pathway analysis with flux balance analysis for the comprehensive study of metabolic systems. , 2000, Biotechnology and bioengineering.

[7]  Biological Hydrogen Production by Enriched Anaerobic Cultures in the Presence of Copper and Zinc , 2004, Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.

[8]  Poonsuk Prasertsan,et al.  Optimization of simultaneous thermophilic fermentative hydrogen production and COD reduction from palm oil mill effluent by Thermoanaerobacterium-rich sludge , 2008 .

[9]  Rangan Banerjee,et al.  Status of Biological hydrogen production , 2008 .

[10]  Anish Kumar,et al.  Effect of some environmental parameters on fermentative hydrogen production by Enterobacter cloacae DM11. , 2006, Canadian journal of microbiology.

[11]  Heguang Zhu,et al.  Evaluation of alternative methods of preparing hydrogen producing seeds from digested wastewater sludge , 2006 .

[12]  T. Wood,et al.  Inhibition of hydrogen uptake in Escherichia coli by expressing the hydrogenase from the cyanobacterium Synechocystis sp. PCC 6803 , 2007, BMC biotechnology.

[13]  Dae Sung Lee,et al.  Optimization of key process variables for enhanced hydrogen production by Enterobacter aerogenes using statistical methods. , 2008, Bioresource technology.

[14]  K. Sakka,et al.  Conversion of chitinous wastes to hydrogen gas by Clostridium paraputrificum M-21. , 2001, Journal of bioscience and bioengineering.

[15]  Hang-Sik Shin,et al.  Effect of gas sparging on continuous fermentative hydrogen production , 2006 .

[16]  Debabrata Das,et al.  ADVANCES IN BIOLOGICAL HYDROGEN PRODUCTION PROCESSES , 2008 .

[17]  Eun Yeol Lee,et al.  Fermentative hydrogen production by a new chemoheterotrophic bacterium Rhodopseudomonas palustris P4 , 2002 .

[18]  A. Ogino,et al.  Hydrogen fermentation properties of undiluted cow dung. , 2007, Journal of bioscience and bioengineering.

[19]  Shangtian Yang,et al.  Construction and Characterization of ack Deleted Mutant of Clostridium tyrobutyricum for Enhanced Butyric Acid and Hydrogen Production , 2008, Biotechnology progress.

[20]  Debabrata Das,et al.  Feasibility studies on the fermentative hydrogen production by recombinant Escherichia coli BL-21 , 2006 .

[21]  K. Shanmugam,et al.  Isolation and characterization of mutated FhlA proteins which activate transcription of the hyc operon (formate hydrogenlyase) of Escherichia coli in the absence of molybdate , 2000 .

[22]  Jianlong Wang,et al.  Effect of Fe2+ concentration on fermentative hydrogen production by mixed cultures , 2008 .

[23]  Godfrey Kyazze,et al.  Continuous dark fermentative hydrogen production by mesophilic microflora: principles and progress , 2007 .

[24]  Franco Cecchi,et al.  Semi-continuous solid substrate anaerobic reactors for H2 production from organic waste: Mesophilic versus thermophilic regime , 2005 .

[25]  Mi‐Sun Kim,et al.  Hydrogen production from food processing wastewater and sewage sludge by anaerobic dark fermentation combined with photo-fermentation , 2001 .

[26]  M. Inui,et al.  Enhanced hydrogen production from glucose using ldh- and frd-inactivated Escherichiacoli strains , 2006, Applied Microbiology and Biotechnology.

[27]  Chiu-Yue Lin,et al.  Heavy metal effects on fermentative hydrogen production using natural mixed microflora , 2008 .

[28]  M. Gorwa,et al.  Molecular characterization and transcriptional analysis of the putative hydrogenase gene of Clostridium acetobutylicum ATCC 824 , 1996, Journal of bacteriology.

[29]  Bruce E Logan,et al.  Biological hydrogen production by Clostridium acetobutylicum in an unsaturated flow reactor. , 2006, Water research.

[30]  Thomas K. Wood,et al.  Directed Evolution of Toluene ortho-Monooxygenase for Enhanced 1-Naphthol Synthesis and Chlorinated Ethene Degradation , 2002, Journal of bacteriology.

[31]  Haijun Yang,et al.  Effect of ferrous iron concentration on anaerobic bio-hydrogen production from soluble starch , 2006 .

[32]  S. F. Baron,et al.  Reconstitution and properties of a coenzyme F420-mediated formate hydrogenlyase system in Methanobacterium formicicum , 1989, Journal of bacteriology.

[33]  Patrik R. Jones,et al.  Construction of a synthetic YdbK-dependent pyruvate:H2 pathway in Escherichia coli BL21(DE3). , 2009, Metabolic engineering.

[34]  Anish Kumar,et al.  Hydrogen production by Rhodobacter sphaeroides strain O.U.001 using spent media of Enterobacter cloacae strain DM11 , 2005, Applied Microbiology and Biotechnology.

[35]  G. Schön,et al.  H2 production of Rhodospirillum rubrum during adaptation to anaerobic dark conditions , 1980, Archives of Microbiology.

[36]  T. Wood,et al.  Metabolically engineered bacteria for producing hydrogen via fermentation , 2007, Microbial biotechnology.

[37]  C. Lin,et al.  Calcium effect on fermentative hydrogen production in an anaerobic up-flow sludge blanket system. , 2006, Water science and technology : a journal of the International Association on Water Pollution Research.

[38]  You-Kwan Oh,et al.  Various hydrogenases and formate-dependent hydrogen production in Citrobacter amalonaticus Y19 , 2008 .

[39]  O. Yenigün,et al.  Inhibition Effects of Zinc and Copper on Volatile Fatty Acid Production During Anaerobic Digestion , 1996 .

[40]  Thomas K. Wood,et al.  Enhanced hydrogen production from glucose by metabolically engineered Escherichia coli , 2007, Applied Microbiology and Biotechnology.

[41]  M Kalim Akhtar,et al.  Engineering of a synthetic hydF-hydE-hydG-hydA operon for biohydrogen production. , 2008, Analytical biochemistry.

[42]  Walid M. Alalayah,et al.  Effect of Environmental Parameters on hydrogen Production using Clostridium Saccharoperbutylacetonicum N1-4(ATCC 13564) , 2009 .

[43]  August Böck,et al.  Nucleotide sequence and expression of an operon in Escherichia coli coding for formate hydrogenylase components , 1990 .

[44]  T. Noike,et al.  Effect of iron concentration on hydrogen fermentation. , 2001, Bioresource technology.

[45]  K. Shanmugam,et al.  Mutational analysis and characterization of the Escherichia coli hya operon, which encodes [NiFe] hydrogenase 1 , 1991, Journal of bacteriology.

[46]  Jianquan Shen,et al.  Hydrogen production in batch culture of mixed bacteria with sucrose under different iron concentrations , 2005 .

[47]  Jean-Paul Schwitzguébel,et al.  Hydrogen production by Clostridium thermolacticum during continuous fermentation of lactose , 2004 .

[48]  Jo‐Shu Chang,et al.  Dark H2 fermentation from sucrose and xylose using H2-producing indigenous bacteria: feasibility and kinetic studies. , 2008, Water research.

[49]  B. Palsson,et al.  Metabolic Flux Balancing: Basic Concepts, Scientific and Practical Use , 1994, Bio/Technology.

[50]  Robert F. Hickey,et al.  The effect of heavy metals on methane production and hydrogen and carbon monoxide levels during batch anaerobic sludge digestion , 1989 .

[51]  David M. Bagley,et al.  Improving the yield from fermentative hydrogen production , 2007, Biotechnology Letters.

[52]  Kenji Morimoto,et al.  Overexpression of a hydrogenase gene in Clostridium paraputrificum to enhance hydrogen gas production. , 2005, FEMS microbiology letters.

[53]  P. Hallenbeck,et al.  The effect of nutrient limitation on hydrogen production by batch cultures of Escherichia coli , 2006 .

[54]  O. Lenz,et al.  [NiFe]-Hydrogenases of Ralstonia eutropha H16: Modular Enzymes for Oxygen-Tolerant Biological Hydrogen Oxidation , 2006, Journal of Molecular Microbiology and Biotechnology.

[55]  K. Furukawa,et al.  Metabolic engineering for solvent productivity by downregulation of the hydrogenase gene cluster hupCBA in Clostridium saccharoperbutylacetonicum strain N1-4 , 2008, Applied Microbiology and Biotechnology.

[56]  A. Hamid,et al.  Trace Metal Effect on Hydrogen Production Using C.acetobutylicum , 2008 .

[57]  Jo‐Shu Chang,et al.  Dark Hydrogen Fermentation from Hydrolyzed Starch Treated with Recombinant Amylase Originating from Caldimonastaiwanensis On1 , 2007, Biotechnology progress.

[58]  C. Chou,et al.  Fedbatch Operation Using Clostridium acetobutylicum Suspension Culture as Biocatalyst for Enhancing Hydrogen Production , 2003, Biotechnology progress.

[59]  A. Pandey,et al.  Reverse micelles as suitable microreactor for increased biohydrogen production , 2008 .

[60]  Jo‐Shu Chang,et al.  Temperature effects on biohydrogen production in a granular sludge bed induced by activated carbon carriers , 2006 .

[61]  Han-Qing Yu,et al.  Inhibitory effects of butyrate on biological hydrogen production with mixed anaerobic cultures. , 2005, Journal of environmental management.

[62]  A. L. Lacey,et al.  Native and mutant nickel–iron hydrogenases: Unravelling structure and function , 2005 .

[63]  Bo Hu,et al.  Pretreatment of methanogenic granules for immobilized hydrogen fermentation , 2007 .

[64]  Richard Sparling,et al.  Hydrogen production by Clostridium thermocellum 27405 from cellulosic biomass substrates , 2006 .

[65]  Jo-Shu Chang,et al.  Exploring optimal environmental factors for fermentative hydrogen production from starch using mixed anaerobic microflora , 2008 .

[66]  R. Lamed,et al.  Effects of Stirring and Hydrogen on Fermentation Products of Clostridium thermocellum , 1988, Applied and environmental microbiology.

[67]  Jianlong Wang,et al.  Inhibitory effect of ethanol, acetic acid, propionic acid and butyric acid on fermentative hydrogen production , 2008 .

[68]  I. Karube,et al.  Cloning and expression of the hydrogenase gene from Clostridium butyricum in Escherichia coli , 1983, FEBS letters.

[69]  D. Cheong,et al.  Bacterial stress enrichment enhances anaerobic hydrogen production in cattle manure sludge , 2006, Applied Microbiology and Biotechnology.

[70]  Samir Kumar Khanal,et al.  Biological hydrogen production: effects of pH and intermediate products , 2003 .

[71]  J. Smith,et al.  Introduction to chemical engineering thermodynamics , 1949 .

[72]  Jianlong Wang,et al.  Influence of Ni(2+) concentration on biohydrogen production. , 2008, Bioresource technology.

[73]  F. Sargent,et al.  Inactivation of the Escherichia coli K-12 twin-arginine translocation system promotes increased hydrogen production. , 2006, FEMS microbiology letters.

[74]  P. Vignais,et al.  HupUV proteins of Rhodobacter capsulatus can bind H2: evidence from the H-D exchange reaction , 1997, Journal of bacteriology.

[75]  Liying Xu,et al.  Biohydrogen production by Ethanoligenens harbinense B49: Nutrient optimization , 2008 .

[76]  F. Kargı,et al.  Bio-hydrogen production from waste materials , 2006 .

[77]  M. Seki,et al.  Hydrogen Production from Glucose by Anaerobes , 2005, Biotechnology progress.

[78]  F. Casse,et al.  Formate hydrogenlyase system in Salmonella typhimurium LT2. , 1977, European journal of biochemistry.

[79]  E. Crabbe,et al.  Influence of initial pH on hydrogen production from cheese whey. , 2005, Journal of biotechnology.

[80]  Hubert Bahl,et al.  Parameters Affecting Solvent Production by Clostridium pasteurianum , 1992, Applied and environmental microbiology.

[81]  S. Tanisho,et al.  Effect of CO2 removal on hydrogen production by fermentation , 1998 .

[82]  Michael Seibert,et al.  Discovery of Two Novel Radical S-Adenosylmethionine Proteins Required for the Assembly of an Active [Fe] Hydrogenase* , 2004, Journal of Biological Chemistry.

[83]  Jianlong Wang,et al.  Kinetic models for fermentative hydrogen production: A review , 2009 .

[84]  William T. Self,et al.  Expression and Regulation of a Silent Operon, hyf, Coding for Hydrogenase 4 Isoenzyme in Escherichia coli , 2004, Journal of bacteriology.

[85]  N. Ren,et al.  Continuous hydrogen production of auto-aggregative Ethanoligenens harbinense YUAN-3 under non-sterile condition , 2008 .

[86]  V. Belle,et al.  Hyperthermostable and oxygen resistant hydrogenases from a hyperthermophilic bacterium Aquifex aeolicus: Physicochemical properties , 2005 .

[87]  C. F. Forster,et al.  Increased hydrogen production by Escherichia coli strain HD701 in comparison with the wild-type parent strain MC4100 , 2003 .

[88]  You-Kwan Oh,et al.  Fermentative biohydrogen production by a new chemoheterotrophic bacterium Citrobacter sp. Y19 , 2003 .

[89]  Jianlong Wang,et al.  Comparison of different pretreatment methods for enriching hydrogen-producing bacteria from digested sludge , 2008 .

[90]  Jana Zabranska,et al.  Developments and constraints in fermentative hydrogen production , 2007 .

[91]  Patrick C. Hallenbeck,et al.  Biological hydrogen production; fundamentals and limiting processes , 2002 .

[92]  E. Papoutsakis,et al.  In vivo methylation in Escherichia coli by the Bacillus subtilis phage phi 3T I methyltransferase to protect plasmids from restriction upon transformation of Clostridium acetobutylicum ATCC 824 , 1993, Applied and environmental microbiology.

[93]  J. R. Kim,et al.  Isolation and characterization of Rhodopseudomonas palustris P4 which utilizes CO with the production of H2 , 1999, Biotechnology Letters.

[94]  Jianlong Wang,et al.  Experimental design methods for fermentative hydrogen production: A review , 2009 .

[95]  Z. Ren,et al.  Characterization of the cellulolytic and hydrogen‐producing activities of six mesophilic Clostridium species , 2007, Journal of applied microbiology.

[96]  Jianlong Wang,et al.  Effect of temperature on fermentative hydrogen production by mixed cultures , 2008 .

[97]  Nanqi Ren,et al.  Influence of gaseous end-products inhibition and nutrient limitations on the growth and hydrogen production by hydrogen-producing fermentative bacterial B49 , 2007 .

[98]  Jo‐Shu Chang,et al.  Fermentative hydrogen production with Clostridium butyricum CGS5 isolated from anaerobic sewage sludge , 2005 .

[99]  S. Haruta,et al.  Characterization of a microorganism isolated from the effluent of hydrogen fermentation by microflora. , 2001, Journal of bioscience and bioengineering.

[100]  D. Ussery,et al.  Design of a Seven-Genome Escherichia coli Microarray for Comparative Genomic Profiling , 2006, Journal of bacteriology.

[101]  Jianlong Wang,et al.  Application of desirability function based on neural network for optimizing biohydrogen production process , 2009 .

[102]  D. Cheong,et al.  Acidogenesis characteristics of natural, mixed anaerobes converting carbohydrate-rich synthetic wastewater to hydrogen , 2006 .

[103]  Shigeharu Tanisho,et al.  Continuous hydrogen production from molasses by fermentation using urethane foam as a support of flocks , 1995 .

[104]  Debabrata Das,et al.  Advances in biohydrogen production processes: An approach towards commercialization , 2009 .

[105]  Monica Riley,et al.  Escherichia coli K-12: a cooperatively developed annotation snapshot—2005 , 2006, Nucleic acids research.

[106]  P. N. Sarma,et al.  Effect of various pretreatment methods on anaerobic mixed microflora to enhance biohydrogen production utilizing dairy wastewater as substrate. , 2008, Bioresource technology.

[107]  Chun-Chin Wang,et al.  Photohydrogen production using purple nonsulfur bacteria with hydrogen fermentation reactor effluent , 2002 .

[108]  R. Dubey,et al.  Enhanced hydrogen production by coupled system of Halobacterium halobium and chloroplast after entrapment within reverse micelles , 1999 .

[109]  Heung-Joo Kim,et al.  Metabolic-flux analysis of hydrogen production pathway in Citrobacter amalonaticus Y19 , 2008 .

[110]  D. Das,et al.  Molecular cloning, characterization, and overexpression of a novel [Fe]-hydrogenase isolated from a high rate of hydrogen producing Enterobacter cloacae IIT-BT 08. , 2004, Biochemical and biophysical research communications.

[111]  K. Shanmugam,et al.  Cloning, sequencing, and mutational analysis of the hyb operon encoding Escherichia coli hydrogenase 2 , 1994, Journal of bacteriology.

[112]  Michael Kornaros,et al.  Hydrogen production from sugars and sweet sorghum biomass using Ruminococcus albus , 2008 .

[113]  Yuansong Wei,et al.  Enhanced biohydrogen production from sewage sludge with alkaline pretreatment. , 2004, Environmental science & technology.

[114]  Han-Qing Yu,et al.  The role of pH in the fermentative H2 production from an acidogenic granule-based reactor. , 2006, Chemosphere.

[115]  E. Papoutsakis,et al.  Genetic manipulation of acid formation pathways by gene inactivation in Clostridium acetobutylicum ATCC 824. , 1996, Microbiology.

[116]  Jianlong Wang,et al.  Optimization of fermentative hydrogen production process using genetic algorithm based on neural network and response surface methodology , 2009 .

[117]  Irini Angelidaki,et al.  Thermophilic fermentative hydrogen production by the newly isolated Thermoanaerobacterium thermosaccharolyticum PSU-2 , 2008 .

[118]  Chiu-Yue Lin,et al.  Fermentative hydrogen production from starch using natural mixed cultures , 2008 .

[119]  Matthew C. Posewitz,et al.  Functional Studies of [FeFe] Hydrogenase Maturation in an Escherichia coli Biosynthetic System , 2006, Journal of bacteriology.

[120]  L. T. Angenent,et al.  Production of bioenergy and biochemicals from industrial and agricultural wastewater. , 2004, Trends in biotechnology.

[121]  P. Hallenbeck,et al.  Fundamentals of the fermentative production of hydrogen. , 2005, Water science and technology : a journal of the International Association on Water Pollution Research.

[122]  J. Lay,et al.  Feasibility of biological hydrogen production from organic fraction of municipal solid waste , 1999 .

[123]  Tong Zhang,et al.  Acidophilic biohydrogen production from rice slurry , 2006 .

[124]  T. Wood,et al.  Escherichia coli hydrogenase 3 is a reversible enzyme possessing hydrogen uptake and synthesis activities , 2007, Applied Microbiology and Biotechnology.

[125]  Jo-Shu Chang,et al.  Biohydrogen production with anaerobic sludge immobilized by ethylene-vinyl acetate copolymer , 2005 .

[126]  R. Banerjee,et al.  Comparison of biohydrogen production processes , 2008 .

[127]  Yutaka Nakashimada,et al.  Hydrogen production of Enterobacter aerogenes altered by extracellular and intracellular redox states , 2002 .

[128]  Chiu-Yue Lin,et al.  A nutrient formulation for fermentative hydrogen production using anaerobic sewage sludge microflora , 2005 .

[129]  Herbert H. P. Fang,et al.  Fermentative Hydrogen Production From Wastewater and Solid Wastes by Mixed Cultures , 2007 .

[130]  Jo-Shu Chang,et al.  Operation strategies for biohydrogen production with a high-rate anaerobic granular sludge bed bioreactor , 2004 .

[131]  Debabrata Das,et al.  Continuous hydrogen production by immobilized Enterobacter cloacae IIT-BT 08 using lignocellulosic materials as solid matrices. , 2001 .

[132]  S. Junne,et al.  Antisense RNA Downregulation of Coenzyme A Transferase Combined with Alcohol-Aldehyde Dehydrogenase Overexpression Leads to Predominantly Alcohologenic Clostridium acetobutylicum Fermentations , 2003, Journal of bacteriology.

[133]  Jun Hirose,et al.  Characteristics of hydrogen production by aciduric Enterobacter aerogenes strain HO-39 , 1995 .

[134]  H. Gest,et al.  FORMIC DEHYDROGENASE AND THE HYDROGENLYASE ENZYME COMPLEX IN COLI-AEROGENES BACTERIA , 1957, Journal of bacteriology.

[135]  Mi-Sun Kim,et al.  Thermophilic biohydrogen production from glucose with trickling biofilter. , 2004, Biotechnology and bioengineering.

[136]  C. Lin,et al.  Biohydrogen production by mesophilic fermentation of food wastewater. , 2004, Water science and technology : a journal of the International Association on Water Pollution Research.

[137]  Chiu-Yue Lin,et al.  Effect of heavy metals on acidogenesis in anaerobic digestion , 1993 .

[138]  Hang-Sik Shin,et al.  Hydrogen production from food waste in anaerobic mesophilic and thermophilic acidogenesis , 2004 .

[139]  Chenlin Li,et al.  Inhibition of heavy metals on fermentative hydrogen production by granular sludge. , 2007, Chemosphere.

[140]  D. Das,et al.  Isolation and evaluation of a high H2-producing lab isolate from cow dung , 2009 .

[141]  Yuzuru Takamura,et al.  Development of a compact high-density microbial hydrogen reactor for portable bio-fuel cell system , 2006 .

[142]  P. Hallenbeck,et al.  Hydrogen production by continuous cultures of Escherchia coli under different nutrient regimes , 2008 .