PTMC and MPEG-PTMC microparticles for hydrophilic drug delivery.

In this study, the potential of PTMC and mPEG-PTMC microparticles for controlled delivery of hydrophilic drugs was investigated. PTMC and mPEG-PTMC microparticles, loaded with hydrophilic model compounds (BSA, lysozyme and CoomassieR Brilliant Blue G) were prepared by the double emulsion method. High loading efficiencies can be achieved, and first order release profiles during 60 days were observed.