Treatment of Contralateral N0 Neck in Early Squamous Cell Carcinoma of the Oral Tongue: Elective Neck Dissection versus Observation

Objectives/Hypothesis: Prophylactic treatment of contralateral N0 neck in early squamous cell carcinoma (SCC) of the oral tongue is a controversial issue. The aim of this study was to analyze the rates of occult metastases and their prognostic effects in stage I and stage II SCC of the oral tongue, and to compare the results of elective neck dissection to observation of the contralateral N0 neck in the treatment of these patients.

[1]  A. Borges,et al.  Elective versus therapeutic neck dissection in early carcinoma of the oral tongue. , 1989, American journal of surgery.

[2]  N. Ghossein,et al.  Experience of the curie institute in treatment of cancer of the mobile tongue. II. Management of the neck nodes , 1981, Cancer.

[3]  D. Soutar,et al.  Improved survival for patients with clinically T1/T2, N0 tongue tumors undergoing a prophylactic neck dissection , 1999, Head & neck.

[4]  K. Lam,et al.  Occult lymph node metastasis in small oral tongue cancers , 1992, Head & neck.

[5]  R. Spiro,et al.  Improved survival in the treatment of squamous carcinoma of the oral tongue. , 1993, American journal of surgery.

[6]  L. Sennaroğlu,et al.  The value of elective neck dissection in treatment of cancer of the tongue. , 2001, American journal of otolaryngology.

[7]  J. Medina,et al.  Supraomohyoid neck dissection: Rationale, indications, and surgical technique , 1989, Head & neck.

[8]  Shinobu Uehara,et al.  Clinical predictors for contralateral neck lymph node metastasis from unilateral squamous cell carcinoma in the oral cavity. , 2004, Oral oncology.

[9]  J Valk,et al.  Cervical lymph node metastasis: assessment of radiologic criteria. , 1990, Radiology.

[10]  R. Spiro,et al.  Epidermoid carcinoma of the mobile tongue. Treatment by partial glossectomy alone. , 1971, American journal of surgery.

[11]  W. B. Litton,et al.  Symposium on malignancy. II. Occult regional metastasis: Carcinoma of the oral tongue , 1972, The Laryngoscope.

[12]  A A Mancuso,et al.  Cervical lymph node metastases: oncologic imaging and diagnosis. , 1984, International journal of radiation oncology, biology, physics.

[13]  N. Ghossein,et al.  Experience of the curie institute in treatment of cancer of the mobile tongue. I. Treatment policies and result , 1981, Cancer.

[14]  J. Teichgraeber,et al.  The incidence of occult metastases for cancer of the oral tongue and floor of the mouth: treatment rationale. , 1984, Head & neck surgery.

[15]  C. Droulias,et al.  Surgical treatment of squamous cell carcinoma of the oral tongue: factors influencing survival. , 1977, Archives of otolaryngology.

[16]  A. Yuen,et al.  Elective neck dissection versus observation in the treatment of early oral tongue carcinoma , 1997, Head & neck.