Practical use of DD-peptidase 64-575 for the assay of inhibition activity of natural and synthetic beta-lactam compounds.

DD-peptidase 64-575 is produced by Saccharopolyspora erythrea PZH TZ 64-575. This enzyme is very sensitive to beta-lactam antibiotics. It could be used to assay the affinity of natural and synthetic beta-lactam compounds. In this paper an enzymatic method is described for investigation of synthetic, insoluble in water beta-lactams.