Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition.
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Christoph Grundner | Wayne A Hendrickson | Marie Pancera | Peter D Kwong | Joseph Sodroski | J. Sodroski | R. Wyatt | W. Hendrickson | P. Kwong | M. Pancera | Liping Wang | Richard Wyatt | Peter Kolchinsky | C. Grundner | Markus Koch | Liping Wang | M. Koch | P. Kolchinsky
[1] Paul E. Kennedy,et al. HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor , 1996, Science.
[2] R. Means,et al. A role for carbohydrates in immune evasion in AIDS , 1998, Nature Medicine.
[3] P. S. Kim,et al. HIV Entry and Its Inhibition , 1998, Cell.
[4] J. Sodroski,et al. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody , 1998, Nature.
[5] C. Barbas,et al. Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120 , 1995, Journal of virology.
[6] Robin A. Weiss,et al. The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain , 1986, Cell.
[7] L. Stamatatos,et al. An Envelope Modification That Renders a Primary, Neutralization-Resistant Clade B Human Immunodeficiency Virus Type 1 Isolate Highly Susceptible to Neutralization by Sera from Other Clades , 1998, Journal of Virology.
[8] J. Sodroski,et al. CD4 Binding Site Antibodies Inhibit Human Immunodeficiency Virus gp120 Envelope Glycoprotein Interaction with CCR5 , 2003, Journal of Virology.
[9] D R Burton,et al. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. , 1994, Science.
[10] J. Hansen,et al. Host cell glycosylation of viral glycoproteins--a battlefield for host defence and viral resistance. , 1998, Scandinavian journal of infectious diseases.
[11] Ying Sun,et al. A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding. , 1998, Science.
[12] Peter D. Kwong,et al. The antigenic structure of the HIV gp120 envelope glycoprotein , 1998, Nature.
[13] J. Sodroski,et al. The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens. , 1998, Science.
[14] I. Chen,et al. Envelope proteins from clinical isolates of human immunodeficiency virus type 1 that are refractory to neutralization by soluble CD4 possess high affinity for the CD4 receptor. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[15] K. Tan,et al. Atomic structure of a thermostable subdomain of HIV-1 gp41. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[16] J. Sodroski,et al. Oligomeric Modeling and Electrostatic Analysis of the gp120 Envelope Glycoprotein of Human Immunodeficiency Virus , 2000, Journal of Virology.
[17] Joseph Sodroski,et al. Envelope Glycoprotein Determinants of Neutralization Resistance in a Simian-Human Immunodeficiency Virus (SHIV-HXBc2P 3.2) Derived by Passage in Monkeys , 2001, Journal of Virology.
[18] J. Sodroski,et al. Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding , 1993, Journal of virology.
[19] L. Stamatatos,et al. Effect of major deletions in the V1 and V2 loops of a macrophage-tropic HIV type 1 isolate on viral envelope structure, cell entry, and replication. , 1998, AIDS research and human retroviruses.
[20] J. Sodroski,et al. Target cell-specific determinants of membrane fusion within the human immunodeficiency virus type 1 gp120 third variable region and gp41 amino terminus , 1992, Journal of virology.
[21] M. Essex,et al. CCR5 coreceptor utilization involves a highly conserved arginine residue of HIV type 1 gp120. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[22] J. Goudsmit,et al. An N-glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization. , 1994, Virology.
[23] J. Nielsen,et al. Resistance to V3-directed neutralization caused by an N-linked oligosaccharide depends on the quaternary structure of the HIV-1 envelope oligomer. , 1996, Virology.
[24] J. Sodroski,et al. Species-Specific, Postentry Barriers to Primate Immunodeficiency Virus Infection , 1999, Journal of Virology.
[25] J. Sodroski,et al. Loss of a Single N-Linked Glycan Allows CD4-Independent Human Immunodeficiency Virus Type 1 Infection by Altering the Position of the gp120 V1/V2 Variable Loops , 2001, Journal of Virology.
[26] Ying Sun,et al. Replicative function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates , 1995, Journal of virology.
[27] J. Hansen,et al. Sensitivity of HIV-1 to neutralization by antibodies against O-linked carbohydrate epitopes despite deletion of O-glycosylation signals in the V3 loop , 2005, Archives of Virology.
[28] Amanda M. Brown,et al. Selection for Neutralization Resistance of the Simian/Human Immunodeficiency Virus SHIVSF33A Variant In Vivo by Virtue of Sequence Changes in the Extracellular Envelope Glycoprotein That Modify N-Linked Glycosylation , 1999, Journal of Virology.
[29] Q. Sattentau,et al. Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding , 1991, The Journal of experimental medicine.
[30] J. Chermann,et al. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). , 1983, Science.
[31] B. Haynes,et al. Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS. , 1984, Science.
[32] C. Broder,et al. CC CKR5: A RANTES, MIP-1α, MIP-1ॆ Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1 , 1996, Science.
[33] M. Hørder,et al. An improved PCR-based method for site directed mutagenesis using megaprimers. , 1998, Molecular and cellular probes.
[34] B. Chesebro,et al. Differences in CD4 dependence for infectivity of laboratory-adapted and primary patient isolates of human immunodeficiency virus type 1 , 1994, Journal of virology.
[35] W A Hendrickson,et al. Energetics of the HIV gp120-CD4 binding reaction. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[36] J. Sodroski,et al. Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants , 1990, Journal of virology.
[37] J. Sodroski,et al. Replication and neutralization of human immunodeficiency virus type 1 lacking the V1 and V2 variable loops of the gp120 envelope glycoprotein , 1997, Journal of virology.
[38] A. Trkola,et al. Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex , 1997, Journal of virology.
[39] Q. Sattentau,et al. Direct measurement of soluble CD4 binding to human immunodeficiency virus type 1 virions: gp120 dissociation and its implications for virus-cell binding and fusion reactions and their neutralization by soluble CD4 , 1991, Journal of virology.
[40] W A Hendrickson,et al. Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates. , 2000, Structure.
[41] Peter D. Kwong,et al. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites , 2002, Nature.
[42] P. Earl,et al. Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[43] Joseph Sodroski,et al. Increased Neutralization Sensitivity of CD4-Independent Human Immunodeficiency Virus Variants , 2001, Journal of Virology.
[44] D R Burton,et al. Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1 , 1994, Journal of virology.
[45] R. Connor,et al. Change in Coreceptor Use Correlates with Disease Progression in HIV-1–Infected Individuals , 1997, The Journal of experimental medicine.
[46] W. Gallaher,et al. Detection of a fusion peptide sequence in the transmembrane protein of human immunodeficiency virus , 1987, Cell.
[47] C. Barbas,et al. Determinants of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Activation by Soluble CD4 and Monoclonal Antibodies , 1998, Journal of Virology.
[48] J. Hansen,et al. Rapid selection for an N-linked oligosaccharide by monoclonal antibodies directed against the V3 loop of human immunodeficiency virus type 1. , 1996, The Journal of general virology.
[49] P. Earl,et al. Folding, assembly, and intracellular trafficking of the human immunodeficiency virus type 1 envelope glycoprotein analyzed with monoclonal antibodies recognizing maturational intermediates , 1996, Journal of virology.
[50] Martin A. Nowak,et al. Antibody neutralization and escape by HIV-1 , 2003, Nature.
[51] Ying Sun,et al. The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates , 1996, Cell.
[52] J. Hansen,et al. The N‐linked glycan of the V3 region of HIV‐1 gp120 and CXCR4‐dependent multiplication of a human immunodeficiency virus type 1 lymphocyte‐tropic variant , 1999, FEBS letters.
[53] Susan Zolla-Pazner,et al. Human Immunodeficiency Virus (HIV) Envelope Binds to CXCR4 Independently of CD4, and Binding Can Be Enhanced by Interaction with Soluble CD4 or by HIV Envelope Deglycosylation , 1998, Journal of Virology.
[54] J. Moore,et al. Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates , 1992, Journal of virology.
[55] J. Sodroski,et al. Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1. , 1987, Science.
[56] J. Sodroski,et al. Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein , 1996, Journal of virology.
[57] J. Sodroski,et al. Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoprotein , 1992, Journal of virology.
[58] D. Kabat,et al. Infectious properties of human immunodeficiency virus type 1 mutants with distinct affinities for the CD4 receptor , 1997, Journal of virology.
[59] Q. Sattentau,et al. Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the gp120 oligomer , 1995, The Journal of experimental medicine.
[60] David Yang,et al. The N-Terminal V3 Loop Glycan Modulates the Interaction of Clade A and B Human Immunodeficiency Virus Type 1 Envelopes with CD4 and Chemokine Receptors , 2000, Journal of Virology.
[61] S. Harrison,et al. Atomic structure of the ectodomain from HIV-1 gp41 , 1997, Nature.
[62] J. Sodroski,et al. Adaptation of a CCR5-Using, Primary Human Immunodeficiency Virus Type 1 Isolate for CD4-Independent Replication , 1999, Journal of Virology.