The role of cellular senescence in ageing of the placenta.

[1]  G. Burton,et al.  Mitochondrial - Endoplasmic reticulum interactions in the trophoblast: Stress and senescence. , 2017, Placenta.

[2]  Tina Bianco-Miotto,et al.  Accelerated placental aging in early onset preeclampsia pregnancies identified by DNA methylation , 2016, Epigenomics.

[3]  M. Hoeltzenbein,et al.  Tocilizumab use in pregnancy: Analysis of a global safety database including data from clinical trials and post-marketing data. , 2016, Seminars in arthritis and rheumatism.

[4]  G. Saade,et al.  Differential senescence in feto-maternal tissues during mouse pregnancy. , 2016, Placenta.

[5]  Sam Mesiano,et al.  Novel concepts on pregnancy clocks and alarms: redundancy and synergy in human parturition. , 2016, Human reproduction update.

[6]  P. Speight,et al.  A miR-335/COX-2/PTEN axis regulates the secretory phenotype of senescent cancer-associated fibroblasts , 2016, Aging.

[7]  G. Tell,et al.  Placental aging and oxidation damage in a tissue micro-array model: an immunohistochemistry study , 2016, Histochemistry and Cell Biology.

[8]  G. Saade,et al.  Placental telomere shortening in stillbirth: a sign of premature senescence? , 2016, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

[9]  L. Dassa,et al.  Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL , 2016, Nature Communications.

[10]  R. Goldenberg,et al.  Global burden of prematurity. , 2016, Seminars in fetal & neonatal medicine.

[11]  A. Amiel,et al.  Telomere homeostasis in IUGR placentas - A review. , 2016, Placenta.

[12]  A. Pezeshki,et al.  Naturally occurring p16Ink4a-positive cells shorten healthy lifespan , 2016, Nature.

[13]  A. Amiel,et al.  Telomere homeostasis in trophoblasts and in cord blood cells from pregnancies complicated with preeclampsia. , 2016, American journal of obstetrics and gynecology.

[14]  M. Velarde,et al.  Placental membrane aging and HMGB1 signaling associated with human parturition , 2016, Aging.

[15]  S. Ben-Dor,et al.  NKG2D ligands mediate immunosurveillance of senescent cells , 2016, Aging.

[16]  C. Mathers,et al.  National, regional, and worldwide estimates of stillbirth rates in 2015, with trends from 2000: a systematic analysis. , 2016, The Lancet. Global health.

[17]  U. Lang,et al.  Placental membrane-type metalloproteinases (MT-MMPs): Key players in pregnancy , 2016, Cell adhesion & migration.

[18]  N. Sharpless,et al.  Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice , 2015, Nature Medicine.

[19]  C. Redman,et al.  Preeclampsia, biomarkers, syncytiotrophoblast stress, and placental capacity. , 2015, American journal of obstetrics and gynecology.

[20]  L. Cox,et al.  Suppression of the senescence-associated secretory phenotype (SASP) in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2 , 2015, Biogerontology.

[21]  L. Zender,et al.  mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype , 2015, Nature Cell Biology.

[22]  Georgia Woods,et al.  Cellular senescence and the aging brain , 2015, Experimental Gerontology.

[23]  P. Nelson,et al.  MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation , 2015, Nature Cell Biology.

[24]  M. Phillippe.  Cell-Free Fetal DNA, Telomeres, and the Spontaneous Onset of Parturition , 2015, Reproductive Sciences.

[25]  Ho Yeon Kim,et al.  The Proteomic Analysis of Human Placenta with Pre-eclampsia and Normal Pregnancy , 2015, Journal of Korean medical science.

[26]  Maximina H. Yun,et al.  Recurrent turnover of senescent cells during regeneration of a complex structure , 2015, eLife.

[27]  N. LeBrasseur,et al.  The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs , 2015, Aging cell.

[28]  Kiyoko Kato,et al.  The effect of progesterone on genes involved in preterm labor. , 2014, Journal of reproductive immunology.

[29]  A. Amiel,et al.  Telomere shortening in intra uterine growth restriction placentas. , 2014, Early human development.

[30]  Manuel Serrano,et al.  Cellular senescence: from physiology to pathology , 2014, Nature Reviews Molecular Cell Biology.

[31]  S. Yagel,et al.  United we stand not dividing: the syncytiotrophoblast and cell senescence. , 2014, Placenta.

[32]  Özge Tunçalp,et al.  Global causes of maternal death: a WHO systematic analysis. , 2014, The Lancet. Global health.

[33]  J. Deursen.  The role of senescent cells in ageing , 2014, Nature.

[34]  W. Średniawa,et al.  Dynamic JUNQ inclusion bodies are asymmetrically inherited in mammalian cell lines through the asymmetric partitioning of vimentin , 2014, Proceedings of the National Academy of Sciences.

[35]  C. Hernández-Guerrero,et al.  An imbalance in the production of proinflammatory and anti-inflammatory cytokines is observed in whole blood cultures of preeclamptic women in comparison with healthy pregnant women , 2014, Hypertension in pregnancy.

[36]  E. Ota,et al.  Risk factors for spontaneous and provider‐initiated preterm delivery in high and low Human Development Index countries: a secondary analysis of the World Health Organization Multicountry Survey on Maternal and Newborn Health , 2014, BJOG : an international journal of obstetrics and gynaecology.

[37]  Thomas Nyström,et al.  The good and the bad of being connected: the integrons of aging. , 2014, Current opinion in cell biology.

[38]  J. Sharpe,et al.  Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning , 2013, Cell.

[39]  A. Rodríguez-Baeza,et al.  Programmed Cell Senescence during Mammalian Embryonic Development , 2013, Cell.

[40]  H. Gal,et al.  Cell fusion induced by ERVWE1 or measles virus causes cellular senescence , 2013, Genes & development.

[41]  Kazuhiro Takahashi,et al.  Targeting interleukin-6 receptor inhibits preterm delivery induced by inflammation. , 2013, Molecular human reproduction.

[42]  G. Liang,et al.  Comparative Proteome Profile of Human Placenta from Normal and Preeclamptic Pregnancies , 2013, PloS one.

[43]  Heather Bradshaw,et al.  Combinatory approaches prevent preterm birth profoundly exacerbated by gene-environment interactions. , 2013, The Journal of clinical investigation.

[44]  J. Andersen,et al.  Environmental stress, ageing and glial cell senescence: a novel mechanistic link to Parkinson's disease? , 2013, Journal of internal medicine.

[45]  R. Aitken,et al.  Unexplained antepartum stillbirth: a consequence of placental aging? , 2013, Placenta.

[46]  M. Beckmann,et al.  Reduced Syncytin-1 Expression Levels in Placental Syndromes Correlates with Epigenetic Hypermethylation of the ERVW-1 Promoter Region , 2013, PloS one.

[47]  A. Amiel,et al.  Senescence in amniocytes and placentas from trisomy 21 pregnancies , 2013, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

[48]  Eric O Long,et al.  Cellular senescence induced by CD158d reprograms natural killer cells to promote vascular remodeling , 2012, Proceedings of the National Academy of Sciences.

[49]  J. Trojanowski,et al.  Astrocyte Senescence as a Component of Alzheimer’s Disease , 2012, PloS one.

[50]  J. Campisi,et al.  Lamin B1 loss is a senescence-associated biomarker , 2012, Molecular biology of the cell.

[51]  C. Lawless,et al.  A senescent cell bystander effect: senescence-induced senescence , 2012, Aging cell.

[52]  N. LeBrasseur,et al.  Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders , 2011, Nature.

[53]  S. Dey,et al.  Heightened uterine mammalian target of rapamycin complex 1 (mTORC1) signaling provokes preterm birth in mice , 2011, Proceedings of the National Academy of Sciences.

[54]  R. Romero,et al.  The "Great Obstetrical Syndromes" are associated with disorders of deep placentation. , 2011, American journal of obstetrics and gynecology.

[55]  A. Amiel,et al.  TERC telomerase subunit gene copy number in placentas from pregnancies complicated with intrauterine growth restriction. , 2011, Early human development.

[56]  B. Viollet,et al.  AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 , 2011, Nature Cell Biology.

[57]  J. Campisi,et al.  Inflammatory networks during cellular senescence: causes and consequences. , 2010, Trends in molecular medicine.

[58]  Jayanta Debnath,et al.  Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease , 2010, PloS one.

[59]  Lloyd A Greene,et al.  Rapamycin Protects against Neuron Death in In Vitro andIn Vivo Models of Parkinson's Disease , 2010, The Journal of Neuroscience.

[60]  A. Amiel,et al.  Short telomeres may play a role in placental dysfunction in preeclampsia and intrauterine growth restriction. , 2009, American journal of obstetrics and gynecology.

[61]  P. Opolon,et al.  Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene , 2009, Proceedings of the National Academy of Sciences.

[62]  Marco Pahor,et al.  Rapamycin fed late in life extends lifespan in genetically heterogeneous mice , 2009, Nature.

[63]  J. Campisi,et al.  Persistent DNA damage signaling triggers senescence-associated inflammatory cytokine secretion , 2009, Nature Cell Biology.

[64]  I. Sargent,et al.  Placental stress and pre-eclampsia: a revised view. , 2009, Placenta.

[65]  S. Ozanne,et al.  DNA damage, cellular senescence and organismal ageing: causal or correlative? , 2007, Nucleic acids research.

[66]  I. Crocker,et al.  Formation of syncytial knots is increased by hyperoxia, hypoxia and reactive oxygen species. , 2007, Placenta.

[67]  H. Chuang,et al.  Altered placental syncytin and its receptor ASCT2 expression in placental development and pre‐eclampsia , 2006, BJOG : an international journal of obstetrics and gynaecology.

[68]  Houeto Jean-Luc.  [Parkinson's disease]. , 2022, La Revue du praticien.

[69]  J. King,et al.  Cyclo-oxygenase (COX) inhibitors for treating preterm labour. , 2005, The Cochrane database of systematic reviews.

[70]  J. Campisi.  Senescent Cells, Tumor Suppression, and Organismal Aging: Good Citizens, Bad Neighbors , 2005, Cell.

[71]  Roberto Romero,et al.  Clinical significance of intra-amniotic inflammation in patients with preterm premature rupture of membranes. , 2004, American journal of obstetrics and gynecology.

[72]  Jung Weon Lee,et al.  Morphological Adjustment of Senescent Cells by Modulating Caveolin-1 Status* , 2004, Journal of Biological Chemistry.

[73]  R. Pearson,et al.  mTOR-Dependent Regulation of Ribosomal Gene Transcription Requires S6K1 and Is Mediated by Phosphorylation of the Carboxy-Terminal Activation Domain of the Nucleolar Transcription Factor UBF† , 2003, Molecular and Cellular Biology.

[74]  D. Olson.  The role of prostaglandins in the initiation of parturition. , 2003, Best practice & research. Clinical obstetrics & gynaecology.

[75]  S. Lowe,et al.  Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence , 2003, Cell.

[76]  O. Genbačev,et al.  Trophoblast origin of hCG isoforms: cytotrophoblasts are the primary source of choriocarcinoma-like hCG , 2002, Molecular and Cellular Endocrinology.

[77]  M. Mitchell,et al.  Cytokines of the placenta and extra-placental membranes: roles and regulation during human pregnancy and parturition. , 2002, Placenta.

[78]  D. Luton,et al.  Overexpression of Copper Zinc Superoxide Dismutase Impairs Human Trophoblast Cell Fusion and Differentiation. , 2001, Endocrinology.

[79]  D. Luton,et al.  Overexpression of copper zinc superoxide dismutase impairs human trophoblast cell fusion and differentiation. , 2001, Endocrinology.

[80]  D. Luton,et al.  Defect of villous cytotrophoblast differentiation into syncytiotrophoblast in Down's syndrome. , 2000, The Journal of clinical endocrinology and metabolism.

[81]  I. Sargent,et al.  Placental debris, oxidative stress and pre-eclampsia. , 2000, Placenta.

[82]  B. Kelley,et al.  Accelerated replicative senescence of medial smooth muscle cells derived from abdominal aortic aneurysms compared to the adjacent inferior mesenteric artery. , 2000, The Journal of surgical research.

[83]  M. Kasuga,et al.  Regulation of eIF-4E BP1 Phosphorylation by mTOR* , 1997, The Journal of Biological Chemistry.

[84]  C Roskelley,et al.  A biomarker that identifies senescent human cells in culture and in aging skin in vivo. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[85]  F. Mannino.  Neonatal complications of postterm gestation. , 1988, The Journal of reproductive medicine.

[86]  P. Yudkin,et al.  RISK OF UNEXPLAINED STILLBIRTH AT DIFFERENT GESTATIONAL AGES , 1987, The Lancet.

[87]  J. Bench,et al.  CHILDREN'S USE OF HEARING-AIDS , 1976, The Lancet.

[88]  L. Hayflick,et al.  The serial cultivation of human diploid cell strains. , 1961, Experimental cell research.

[89]  R. Richart.  Studies of Placental Morphogenesis I. Radioautographic Studies of Human Placenta Utilizing Tritiated Thymidine.∗ , 1961, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.